Measurement equivalence and feasibility of the EORTC QLQ-PR25: paper-and-pencil versus touch-screen administration

Table 3 Mean scores and equivalence test between touch-screen and paper-and-pencil modes

	Paper-and-pencil		Touch-screen		Equivalence test^c
EORTC QLQ-PR25^a	Mean	SD	Mean	SD	95% CI of	Left tail^e	Right tail^e
EORTC QLQ-PR25^a	Mean	SD	Mean	SD	Mean difference^d	p-value	p-value
Urinary symptoms (8 items)	19.5	13.5	21.1	13.3	−3.3 to 0.1	<0.001	<0.001
Bowel symptoms (4 items)	5.3	8.6	5.7	7.9	−1.5 to 1.0	<0.001	<0.001
Treatment-related symptoms (6 items)	11.1	10.2	10.3	9.2	−1.1 to 2.9	<0.001	<0.001
Sexual activity (2 items)	19.4	20.2	20.2	20.8	−5.0 to 2.3	0.048	<0.001
Sexual functioning (4 items)^b	62.3	22.0	61.8	20.9	−5.7 to 9.5	0.076	0.415

^aAll scores were linearly converted to a 0 to 100 scale, with higher scores indicating a higher level of functioning and more severe symptoms.
^bSexual functioning items are conditional and only applicable to those being sexually active. A total of 48 patients reported being sexually active in this study.
^cBased on the equivalence test using the score 5 as the tolerably difference.
^dMean difference = paper-and-pencil mean score - touch-screen mean score.
^eLeft tail significance indicates μ_paper – μ_touch-screen > −5. Right tail significance indicated μ_paper – μ_touch-screen < 5. Therefore, both tails significance indicates | μ_paper – μ_touch-screen | < 5.

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