A comparison of four different approaches to measuring health utility in depressed patients

Table 2 Ability of instruments to discriminate between levels of depression severity

Depression severity groups	Utility score means by depression severity group *mean (SD)*		Mean difference in health utility score	Tukey-Kramer test statistic (critical value = 3.649)^
EQ-5D-3L:
Not depressed vs Mild depression	0.797 (0.226)	0.670 (0.243)	0.128	4.242*
Mild depression vs Moderate depression	0.670 (0.243)	0.557 (0.295)	0.112	3.272
Moderate depression vs Severe depression	0.557 (0.295)	0.268 (0.352)	0.289	9.641*
EQ-5D VAS:
Not depressed vs Mild depression	0.713 (0.239)	0.586 (0.229)	0.127	5.247*
Mild depression vs Moderate depression	0.586 (0.229)	0.561 (0.209)	0.025	0.901
Moderate depression vs Severe depression	0.561 (0.209)	0.422 (0.211)	0.139	5.693*
SF-6D:
Not depressed vs Mild depression	0.725 (0.137)	0.624 (0.119)	0.102	7.843*
Mild depression vs Moderate depression	0.624 (0.119)	0.554 (0.096)	0.070	4.733*
Moderate depression vs Severe depression	0.554 (0.096)	0.482 (0.107)	0.072	5.505*
SF-12 new algorithm:
Not depressed vs Mild depression	0.732 (0.139)	0.617 (0.096)	0.116	9.796*
Mild depression vs Moderate depression	0.617 (0.096)	0.564 (0.073)	0.053	3.927*
Moderate depression vs Severe depression	0.564 (0.073)	0.505 (0.083)	0.059	4.947*

^The critical values for each comparison were the same at three decimal places.
* Indicates a test statistic greater than the critical value from the Studentized range distribution at the 5% alpha level.

ISSN: 1477-7525