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Table 5 Patient-reported outcome measures in patients with autoimmune thyroid disease and matched healthy control subjects

From: Patient-reported outcomes in adequately treated hypothyroidism – insights from the German versions of ThyDQoL, ThySRQ and ThyTSQ

Patient-reported outcomes

Treated patient group n = 18

Healthy control group n = 18

p- value

 

Mean

SD

Mean

SD

 

ThySRQ symptom number*

5.44

2.83

2.93

2.63

<0.05

ThyDQoL Present QoL

1.17

0.92

1.61

0.78

n.s.

Hamilton Depression Scale

6.00

3.76

3.72

2.35

=0.06

Beck Depression Inventory*

5.67

4.65

3.00

3.55

<0.05

Short Form-36 physical

54.80

8.50

56.07

5.07

n.s.

Short Form-36 mental

42.93

11.14

49.28

6.81

=0.09

WBQ-12

23.72

5.36

27.78

4.44

<0.05

SCL-90-R

0.39

0.28

0.35

0.33

n.s.

ThySRQ tiredness*

1.67

0.91

0.60

0.63

<0.0033

  1. *Only available in n = 15 healthy control subjects, excluding the same subjects for all analyses does not change any of the results. Abbreviations: SD – Standard Deviation, WBQ – Well-Being Questionnaire, SCL – Symptom Check List, ThyDQoL – Thyroid-Dependent Quality of Life Questionnaire, ThySRQ – Underactive Thyroid Symptom Rating Questionnaire, QoL – Quality of Life.