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Table 3 Characteristics of PROQOL participants

From: HIV-related stigma and physical symptoms have a persistent influence on health-related quality of life in Australians with HIV infection

Variables ALL Not on Rx NNRTI PI p-value
  N = 102 N = 15 N = 46 N = 41  
Female 15 (14.7%) 4 (26.7%) 7 (15.2%) 4 (9.8%) p=0.3
Age 46 (37–53.8) 41 (32.5-49.5) 48 (37–56.5) 45 (40–53) p=0.4
Transmission      p=0.08
Heterosexual/other 42 (41.2%) 10 (66.7%) 21 (45.7%) 11 (26.8%)  
IDU 6 (5.9%) 0 (0%) 3 (6.5%) 3 (7.3%)  
MSM 54 (52.9%) 5 (33.3%) 22 (47.8%) 27 (65.9%)  
Married 34 (33.3%) 5 (33.3%) 17 (37%) 12 (29.3%) p=0.7
Caucasian 80 (78.4%) 9 (60%) 37 (80.4%) 34 (82.9%) p=0.2
Living alone 40 (39.2%) 8 (53.3%) 16 (34.8%) 16 (39%) p=0.5
Post-secondary 37 (36.3%) 6 (40%) 17 (37%) 14 (34.1%) p=0.9
Unemployed/sickness benefits 18 (17.6%) 2 (13.3%) 3 (6.5%) 13 (31.7%) p=0.007
Smoker ≥ 2 cigarettes/day 41 (40.2%) 4 (26.7%) 19 (41.3%) 18 (43.9%) p=0.0002
Alcohol ≥ 2 glasses/day 15 (14.7%) 1 (6.7%) 7 (15.2%) 7 (17.1%) p=0.5
Diagnosed < 2 years 16 (15.7%) 8 (53.3%) 6 (13%) 2 (4.9%) p=0.7
Time since diagnosis (years) 7.3 (2.9-15.6) 1.5 (0.8-3.8) 6.8 (3.2-11.9) 13.2 (6.2-18.9) p<0.0001
Body mass index 24.3 (22–28) 23.6 (22–28) 25.4 (23–28) 23.9 (22–27) p=0.5
CD4 T cells 530 (376–733) 546 (512–695) 591 (386–853) 455 (323–638) p=0.1
Undetectable VL 77 (75.5%) 2 (13.3%) 43 (93.5%) 32 (78%) p<0.0001
Time on ART (years) 4.2 (0.8-11.8) - 4.4 (2.1-9.9) 10.7 (3.2-13.6) p<0.0001
On non-ART medication 38 (37.3%) 3 (20%) 15 (32.6%) 20 (48.8%) p=0.1
ART pill burden (tablets/day) 3 (2–5) - 2.5 (2–3) 4 (3–5) p<0.0001
Non-adherent to ART 18 (17.6%) - 7 (15.2%) 11 (26.8%) p=0.2
Depressive 26 (25.5%) 3 (20%) 8 (17.4%) 15 (36.6%) p=0.1
Other comorbidity 56 (54.9%) 8 (53.3%) 20 (43.5%) 28 (68.3%) p=0.07
Sexual dysfunction 25 (24.5%) 4 (26.7%) 9 (19.6%) 12 (29.3%) p=0.5
Number symptoms (total) 5 (2–10) 4 (1–10.5) 5 (1–8) 8 (5–12) p=0.01
  1. For categorical variables, values are N(%) and the p-value corresponds to a Fisher exact test of equal proportions across treatment groups; for continuous variables, values are median (interquartile range) with the p-values reflecting differences across the treatment groups as assessed by a Kruskal-Wallis test.