Table 1 Intercontinental Childhood ITP Study group (ICIS) staging

I

No bleeding.

And Platelet count above 20 × 10⁹/L.

II

Bruising, petechiae of skin or occasional epistaxis.

Little or no interference with daily living.

And Platelet count above 10 × 10⁹/L.

III

Bruising, petechiae of skin.

Mucosal lesions.

Epistaxis requiring wicking and hemorrhage.

And Platelet count above 10 × 10⁹/L.

IV

Bleeding: epistaxis, melena and/or hemorrhage requiring hospitalization and/or transfusion.

Serious interference with quality of life.

Or Platelet count below 10 × 10⁹/L and/or haemoglobin decrease over 2 g/dl.