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Table 5 Significant HRQoL predictors of HU from stepwise regression model without adjustment for baseline patient characteristics: EU and Non-EU cohorts

From: Use of health-related quality of life measures to predict health utility in postmenopausal osteoporotic women: results from the Multiple Outcomes of Raloxifene Evaluation study

Non-EU Cohort EU Cohort
OPAQ vs. HUI NHP vs. HUI QualEFFO vs. EQ-5D NHP vs. EQ-5D
n = 677 n = 662 n = 538 n = 495
OPAQ domain C NHP domain C QualEFFO domain C NHP Domain C
Walking/Bending 0.184 Pain −0.188 Daily activity 0.689 Pain −0.275
Back pain 0.097 Emotional reaction −0.104 Mental health 0.327 Emotional reaction −0.326
Level of tension 0.084 Physical mobility −0.139 Pain 0.158 Physical mobility −0.274
Fear of falls 0.101 Sleep −0.067 Mobility 0.132* Energy −0.089*
Fatigue 0.077* Energy −0.055*     
   Social interaction −0.099*     
Variance explained 0.41 Variance explained 0.44 Variance explained 0.61 Variance Explained 0.53
  1. Abbreviations: C Regression coefficient, EU European Union, HUI Health Utility Index, NHP Nottingham Health Profile, Non-EU Non-European Union, OPAQ Osteoporosis Assessment Questionnaire, QualEFFO EU Foundation of Osteoporosis Quality-of-Life Assessment.
  2. Scoring: OPAQ scores: 0 (worst) - 100 (best), HUI scores: 0 (worst) -1.0 (best), NHP scores: 0 (best) - 100 (worst), EQ-5D scores: 0 (worst) - 1.0 (best), QualEFFO scores (54-item QualEFFO): 0 (worst) - 100 (best).
  3. *p < 0.05, p < 0.0001 for all other coefficients.