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Table 5 Significant HRQoL predictors of HU from stepwise regression model without adjustment for baseline patient characteristics: EU and Non-EU cohorts

From: Use of health-related quality of life measures to predict health utility in postmenopausal osteoporotic women: results from the Multiple Outcomes of Raloxifene Evaluation study

Non-EU Cohort

EU Cohort

OPAQ vs. HUI

NHP vs. HUI

QualEFFO vs. EQ-5D

NHP vs. EQ-5D

n = 677

n = 662

n = 538

n = 495

OPAQ domain

C

NHP domain

C

QualEFFO domain

C

NHP Domain

C

Walking/Bending

0.184

Pain

−0.188

Daily activity

0.689

Pain

−0.275

Back pain

0.097

Emotional reaction

−0.104

Mental health

0.327

Emotional reaction

−0.326

Level of tension

0.084

Physical mobility

−0.139

Pain

0.158

Physical mobility

−0.274

Fear of falls

0.101

Sleep

−0.067

Mobility

0.132*

Energy

−0.089*

Fatigue

0.077*

Energy

−0.055*

    
  

Social interaction

−0.099*

    

Variance explained

0.41

Variance explained

0.44

Variance explained

0.61

Variance Explained

0.53

  1. Abbreviations: C Regression coefficient, EU European Union, HUI Health Utility Index, NHP Nottingham Health Profile, Non-EU Non-European Union, OPAQ Osteoporosis Assessment Questionnaire, QualEFFO EU Foundation of Osteoporosis Quality-of-Life Assessment.
  2. Scoring: OPAQ scores: 0 (worst) - 100 (best), HUI scores: 0 (worst) -1.0 (best), NHP scores: 0 (best) - 100 (worst), EQ-5D scores: 0 (worst) - 1.0 (best), QualEFFO scores (54-item QualEFFO): 0 (worst) - 100 (best).
  3. *p < 0.05, p < 0.0001 for all other coefficients.
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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