Figure 1

Article selection flow chart for UI due to NDO publications. Reasons for exclusion: A. Editorials, letters, case reports, lectures, news, comment, legal cases, newspaper article, technical report, and clinical trial studies. B. Studies on urinary incontinence (UI) due to idiopathic detrusor overactivity or idiopathic overactive bladder.* C Studies in patients with neurogenic detrusor overactivity (NDO) with urgency but without UI (DRY). D. Studies on stress UI. E. Studies in patients with NDO that is not associated with multiple sclerosis (MS), spinal cord injury (SCI), Parkinson’s disease (PD), stroke, or spina bifida (SB). F. Studies in children or adolescents (<18 years of age) with MS, SCI, PD, or stroke. G. Studies in patients with overactive bladder (OAB) that do not report results specific to urgency UI. H. Studies not requiring patients to have urgency. I. Small (n < 30) case series. J. Studies from countries other than the US, EU 5 (UK, France, Germany, Italy and Spain), Canada, Australia, Thailand, South Korea, and Taiwan. K. Studies that do not specifically discuss the economic or humanistic burden of UI due to NDO from MS, SCI, PD, stroke, or SB. Note: Studies in children or adolescents (<18 years of age) diagnosed with SB were included in the systematic review. * Did not apply to economic studies.