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Table 2 Patient characteristics by tophi and frequency of gout flares

From: Tophi and frequent gout flares are associated with impairments to quality of life, productivity, and increased healthcare resource use: Results from a cross-sectional survey

  Number of self-reported tophi Number of self-report flares in past 12 months
No tophi (n =349) Not sure (n = 195) Any tophi (n = 76) 0/don’t recall (n = 151) 1 to 2 (n = 235) 3 (n = 91) 4 to 5 (n = 86) 6+ (n = 57)
n % n % n % n % n % n % n % n %
Male 293 84% 154 79% 57 75.0% 127 84% 202 86% 67 74% 66 77% 42 74%
Age M (SD) 61.6 (11.2) 61.1 (11.6) 57.0 (12.6) 62.0 (11.2) 61.3 (11.2) 59.9 (12.9) 59.1 (11.9) 60.5 (11.1)
Length of illness (years) M (SD) 11.9 (10.4) 11.6 (11.4) 13.3 (10.0) 13.5 (12.0) 12.1 (10.1) 10.6 (10.5) 9.6 (7.6) 13.5 (12.7)
Employed 140 40.1% 69 35.4% 30 39.5% 54 35.8% 94 40.0% 38 41.8% 29 33.7% 24 42.1%
Medication
  Allopurinol 182 52.1% 94 48.2% 43 56.6% 91 60.3% 104 44.3% 46 50.5% 48 55.8% 30 52.6%
  Febuxostat 8 2.3% 5 2.6% 16 21.1% 4 2.6% 11 4.7% 5 5.5% 4 4.7% 5 8.8%
  Probenecid 8 2.3% 4 2.1% 6 7.9% 6 4% 6 2.6% 2 2.2% 2 2.3% 2 3.5%
  Benzbromarone 0 0% 0 0% 4 5.3% 0 0% 1 0.4% 1 1.1% 2 2.3% 0 0%
  Other 45 12.9% 40 20.5% 12 15.8% 5 3.3% 32 13.6% 74 18.7% 26 30.2% 17 29.8%
  none 120 34.4 63 32.3 11 14.5% 48 31.8% 90 38.3% 27 29.7% 17 19.8% 12 21.1%
  sUA
  Unknown 253 72.5% 152 77.9% 43 56.6% 116 76.8% 168 71.5% 65 71.4% 57 66.3% 42 73.7%
  <6 mg/d 45 12.9% 13 6.7% 4 5.3% 23 15.2% 28 11.9% 4 4.4% 5 5.8% 2 3.5%
  6-8 mg/dL 40 11.5% 19 9.7% 16 21.1% 6 4% 30 12.8% 18 19.8% 15 17.4% 6 10.5%
  >8 mg/dL 11 3.2% 11 5.6% 13 17.1% 6 4% 9 3.8% 4 4.4% 9 10.5% 7 12.3%
Tophi
  No tophi - - - - - - 109 72.2% 142 60.4% 44 48.4% 33 38.4% 21 36.8%
  Not sure - - - - - - 38 25.2% 65 27.7% 33 36.3% 34 39.5% 25 43.9%
  Any tophi - - - - - - 4 2.6% 28 11.9% 14 15.4% 19 22.1% 11 19.3%
Flares
  0/don’t recall 109 31.2% 38 19.5% 4 5.3% - - - - - - - - - -
  1 to 2 142 40.7% 65 33.3% 28 36.8% - - - - - - - - - -
  3 44 12.6% 33 16.9% 14 18.4% - - - - - - - - - -
  4 to 5 33 9.5% 34 17.4% 19 25.0% - - - - - - - - - -
  6+ 21 6.0% 25 12.8% 11 14.5% - - - - - - - - - -