From: Impact of Nausea and Vomiting on Quality of Life in Cancer Patients During Chemotherapy
Author [ref.] | Pts (no.) | Cancer (type) | Chemotherapy (emetogenicity) | Antiemetics | HRQL assessment (times) | Selection of pts |
---|---|---|---|---|---|---|
Lindley [8] | 122 | various | various | various | FLIC and FLIE (before and after 3 days) | 162 pts eligible, 140 agreed to participate, 122 evaluated HRQL |
Berry [10] | 109 | various | various | OND use compassionate | FLIE (n.s.) | 350 pts, 190 received similar CT, 109 evaluated HRQL |
O'Brien [11] | 92 | various | Moderately and highly | DEX + MTC or PCP ± other | FLIE (before and after 2 and 5 days) | 128 pts eligible, 112 agreed to participate, 107 evaluated HRQL (15 pts excluded for multiple days CT) |
Osoba [12] | 802 | various | Moderately and highly | 5-HT3 ± DEX | EORTC QLQ-C30 (before and after 7 days) |  |
Osoba [13] | 802 | various | Moderately and highly | 5-HT3 ± DEX | EORTC QLQ-C30 (before and after 7 days) | Possible selection bias at HRQL evaluated before 2nd cycle CT (70% of pts) |
Rusthoven [16] | 119 | various | Moderately | Standard for Centers | EORTC QLQ-C30 (before and after 2 and 6 days) | 124 pts eligible, 119 evaluated HRQL |