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Table 1 Studies without comparative purpose

From: Impact of Nausea and Vomiting on Quality of Life in Cancer Patients During Chemotherapy

Author [ref.]

Pts (no.)

Cancer (type)

Chemotherapy (emetogenicity)

Antiemetics

HRQL assessment (times)

Selection of pts

Lindley [8]

122

various

various

various

FLIC and FLIE (before and after 3 days)

162 pts eligible, 140 agreed to participate, 122 evaluated HRQL

Berry [10]

109

various

various

OND use compassionate

FLIE (n.s.)

350 pts, 190 received similar CT, 109 evaluated HRQL

O'Brien [11]

92

various

Moderately and highly

DEX + MTC or PCP ± other

FLIE (before and after 2 and 5 days)

128 pts eligible, 112 agreed to participate, 107 evaluated HRQL (15 pts excluded for multiple days CT)

Osoba [12]

802

various

Moderately and highly

5-HT3 ± DEX

EORTC QLQ-C30 (before and after 7 days)

 

Osoba [13]

802

various

Moderately and highly

5-HT3 ± DEX

EORTC QLQ-C30 (before and after 7 days)

Possible selection bias at HRQL evaluated before 2nd cycle CT (70% of pts)

Rusthoven [16]

119

various

Moderately

Standard for Centers

EORTC QLQ-C30 (before and after 2 and 6 days)

124 pts eligible, 119 evaluated HRQL

  1. CT: chemotherapy, DEX: dexamethasone, HRQL: Health-related quality of life, OND: ondansetron, PCP: prochlorperazine, 5-HT3: 5-HT3 antagonist, n.s.: not specified.