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Table 3 Adjusted health-related quality of life measures, stratified by CD4 count (N = 3772)

From: Self-reported health-related quality of life in persons with HIV infection: results from a multi-site interview project

Disability Measure CD4 <200 (n = 1950) (reference) CD4 200–499 (n = 812) CD4 ≥ 500 (n = 259) CD4 Unknown (n = 751)
  mean 95% CL mean 95% CL mean 95% CL mean 95% CL
Overall Health 45.5 42.7–48.2 56.8a 53.7–59.9 64.7b,c 60.3–69.0 49.4 46.2–52.7
Pain 61.8 58.6–65.0 67.6 64.0–71.2 71.6c 66.6–76.6 64.8 61.0–68.5
Physical Functioning 56.6 53.4–59.7 70.7a 67.2–74.2 78.1c 73.2–83.1 67.0 63.3–70.7
Role Functioning 41.3 37.0–45.6 61.9a 57.0–66.7 74.9b,c 68.0–81.7 58.3 53.2–63.4
Social Functioning 61.8 58.7–64.9 75.3a 71.8–78.8 84.3b,c 79.4–89.1 70.5 66.9–74.2
Mental Health 57.1 54.8–59.3 59.1 56.5–61.6 61.1 57.5–64.6 58.7 56.0–61.3
Energy/Fatigue 45.4 43.0–47.7 53.3a 50.6–55.9 58.8c 55.0–62.5 49.8 47.0–52.6
Cognitive Functioning 71.0 68.6–73.4 74.2 71.5–76.9 76.4 72.7–80.2 78.0 75.2–80.8
  1. least-squares means analysis; Tukey-Kramer adjustment for multiple comparisons; significance level P<0.05;
  2. * includes 318 persons who never had a CD4 test
  3. a significant pairwise difference: CD4 < 200 vs. CD4 200–499;
  4. b significant pairwise difference: CD4 200–499 vs. CD4 ≥ 500;
  5. c significant pairwise difference: CD4 < 200 vs. CD4 ≥ 500;
  6. CL= confidence limit
  7. factors in model: age, education, sex, race/ethnicity, HIV risk, health insurance status, income time known HIV+, current antiretroviral status, type of recruitment