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Table 4 Univariate and multivariate linear regression analyses of influencing factors associated with EQ-5D-5L utility and EQ-VAS scores, respectively

From: Health-related quality of life among patients with knee osteoarthritis in Guangzhou, China: a multicenter cross-sectional study

Variable

EQ-5D-5L utility score

EQ-VAS score

Univariate Models

Multivariate Model

Univariate Models

Multivariate Model

\(\beta \left(95\% \mathrm{CI}\right)\)

\(p\)

\(\beta \left(95\% \mathrm{CI}\right)\)

\(p\)

\(\beta \left(95\% \mathrm{CI}\right)\)

\(p\)

\(\beta \left(95\% \mathrm{CI}\right)\)

\(p\)

Location

 Hospital A

Reference

 

Reference

 

Reference

 

Reference

 

 Hospital B

-0.071 (-0.128, -0.015)

0.014

0.008 (-0.039, 0.055)

0.739

2.947 (-1.069, 6.962)

0.150

5.128 (1.036, 9.219)

0.014

 Hospital C

0.006 (-0.038, 0.051)

0.782

0.008 (-0.028, 0.043)

0.660

1.625 (-1.549, 4.799)

0.315

1.575 (-1.527, 4.677)

0.319

 Hospital D

-0.357 (-0.457, -0.257)

 < 0.001

-0.253 (-0.336, -0.171)

 < 0.001

-1.156 (-8.251, 5.938)

0.749

1.025 (-6.227, 8.277)

0.781

Age, years

  < 60

Reference

 

Reference

 

Reference

 

Reference

 

 60–74

-0.053 (-0.102, -0.005)

0.032

0.011 (-0.027, 0.049)

0.559

-1.554 (-4.899, 1.790)

0.362

0.250 (-3.056, 3.557)

0.882

  > 74

-0.133 (-0.193, -0.072)

 < 0.001

-0.013 (-0.061, 0.035)

0.593

-0.896 (-5.057, 3.266)

0.673

2.260 (-1.925, 6.446)

0.289

Cardiovascular disease

 No

Reference

 

Reference

 

Reference

 

Reference

 

 Yes

-0.188 (-0.271, -0.105)

 < 0.001

-0.068 (-0.133, -0.003)

0.042

-5.528 (-11.214, 0.158)

0.057

-4.501 (-10.215, 1.213)

0.122

Daily exercise, minutes

 None

Reference

 

Reference

 

Reference

 

Reference

 

  < 30

0.132 (0.080, 0.183)

 < 0.001

0.053 (0.012, 0.094)

0.012

0.009 (-3.581, 3.599)

0.996

-1.032 (-4.632, 2.567)

0.573

\(\ge\) 30

0.122 (0.076, 0.167)

 < 0.001

0.046 (0.008, 0.083)

0.017

2.154 (-1.015, 5.323)

0.182

0.593 (-2.688, 3.874)

0.723

BMI,\(\mathrm{kg}/{\mathrm{m}}^{2}\)

  < 18.5

-0.349 (-0.540, -0.159)

 < 0.001

-0.159 (-0.306, -0.012)

0.034

-12.324 (-25.264, 0.616)

0.062

-10.066 (-22.922, 2.791)

0.125

 18.5–24

Reference

 

Reference

 

Reference

 

Reference

 

 24–28

-0.045 (-0.095, 0.004)

0.073

-0.029 (-0.067, 0.009)

0.130

-2.824 (-6.194, 0.546)

0.100

-2.546 (-5.849, 0.757)

0.131

  > 28

-0.054 (-0.107, -0.001)

0.045

-0.026 (-0.067, 0.015)

0.210

-4.874 (-8.454, -1.294)

0.008

-4.768 (-8.332, -1.203)

0.009

KOOS-PS, per sda

-0.134 (-0.151, -0.118)

 < 0.001

-0.102 (-0.119, -0.085)

 < 0.001

-3.119 (-4.466, -1.772)

 < 0.001

-2.479 (-3.975, -0.983)

0.001

Pain-VAS, per sdb

-0.089 (-0.108, -0.070)

 < 0.001

-0.054 (-0.071, -0.038)

 < 0.001

-2.676 (-4.031, -1.322)

 < 0.001

-2.063 (-3.499, -0.626)

0.005

  1. Abbreviations: EQ-5D-5L utility score a single index ‘utility’ score representing the EQ-5D-5L health states, EQ-VAS score EQ visual analogue scale; \(\beta \left(95\% \mathrm{CI}\right)\), regression coefficient (95% confidence interval)
  2. aKOOS-PS, sd = 14.739  
  3. bPain-VAS, sd = 2.60 Â