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Table 1 Sociodemographic characteristics of KOA patients and their association with HRQoL (i.e., EQ-5D-5L utility and EQ-VAS scores)

From: Health-related quality of life among patients with knee osteoarthritis in Guangzhou, China: a multicenter cross-sectional study

Characteristic

\(\mathrm{No}. (\mathrm{\%})\)

EQ-5D-5L utility score

EQ-VAS score

mean ± sd

p

mean ± sd

p

Location

 Hospital A

164 (31.599)

0.713 \(\pm\) 0.224

 < 0.001

66.793 \(\pm\) 16.789

0.434

 Hospital B

96 (18.497)

0.642 \(\pm\) 0.246

 

69.740 \(\pm\) 17.137

 

 Hospital C

237 (45.665)

0.720 \(\pm\) 0.211

 

68.418 \(\pm\) 15.184

 

 Hospital D

22 (4.239)

0.356 \(\pm\) 0.249

 

65.636 \(\pm\) 9.810

 

Sex

 Male

115 (22.158)

0.709 \(\pm\) 0.269

0.275

70.565 \(\pm\) 17.248

0.053

 Female

404 (77.842)

0.682 \(\pm\) 0.225

 

67.309 \(\pm\) 15.443

 

Age, years

  < 60

125 (24.085)

0.744 \(\pm\) 0.182

 < 0.001‡

69.080 \(\pm\) 18.070

0.655

 60–74

291 (56.069)

0.691 \(\pm\) 0.240

 

67.526 \(\pm\) 14.971

 

  > 74

103 (19.846)

0.611 \(\pm\) 0.262

 

68.184 \(\pm\) 15.742

 

Marital status

 Unmarried

59 (11.368)

0.650 \(\pm\) 0.272

0.186

67.203 \(\pm\) 16.534

0.672

 Married

460 (88.632)

0.693 \(\pm\) 0.230

 

68.137 \(\pm\) 15.834

 

Smoking status

 No

487 (93.834)

0.691 \(\pm\) 0.230

0.446‡

67.992 \(\pm\) 15.941

0.828

 Yes

32 (6.166)

0.647 \(\pm\) 0.314

 

68.625 \(\pm\) 15.523

 

Alcohol consumption

 No

494 (95.183)

0.687 \(\pm\) 0.235

0.844

68.113 \(\pm\) 15.674

0.600

 Yes

25 (4.817)

0.697 \(\pm\) 0.262

 

66.400 \(\pm\) 20.189

 

Income, CNY +

  < 2000

245 (48.134)

0.683 \(\pm\) 0.251

0.060

67.053 \(\pm\) 16.729

0.105

 2000–4000

187 (36.739)

0.676 \(\pm\) 0.228

 

68.551 \(\pm\) 14.387

 

  > 4000

77 (15.128)

0.749 \(\pm\) 0.192

 

71.364 \(\pm\) 15.317

 

Medical insurance

 No

477 (91.908)

0.684 \(\pm\) 0.236

0.203

68.388 \(\pm\) 15.934

0.085

 Yes

42 (8.092)

0.732 \(\pm\) 0.235

 

63.976 \(\pm\) 15.120

 

Duration of illness, years

  < 5

232 (44.701)

0.690 \(\pm\) 0.255

0.111

69.151 \(\pm\) 16.631

0.216

 6–15

210 (40.462)

0.704 \(\pm\) 0.211

 

67.690 \(\pm\) 15.525

 

  > 15

77 (14.836)

0.638 \(\pm\) 0.234

 

65.584 \(\pm\) 14.480

 

Cardiovascular disease

 No

487 (93.834)

0.700 \(\pm\) 0.224

0.003‡

68.372 \(\pm\) 15.916

0.057

 Yes

32 (6.166)

0.511 \(\pm\) 0.325

 

62.844 \(\pm\) 14.975

 

Total knee arthroplasty

 No

468 (90.173)

0.695 \(\pm\) 0.227

0.111‡

68.325 \(\pm\) 15.844

0.202

 Yes

51 (9.827)

0.625 \(\pm\) 0.299

 

65.333 \(\pm\) 16.332

 

Other joint diseases

 No

462 (89.017)

0.693 \(\pm\) 0.232

0.196

68.253 \(\pm\) 15.840

0.365

 Yes

57 (10.983)

0.650 \(\pm\) 0.261

 

66.228 \(\pm\) 16.419

 

Trauma or ligament injury

 No

423 (81.503)

0.690 \(\pm\) 0.236

0.711

67.809 \(\pm\) 16.173

0.504

 Yes

96 (18.497)

0.680 \(\pm\) 0.235

 

69.010 \(\pm\) 14.683

 

Daily exercise, minutes

 None

183 (35.260)

0.607 \(\pm\) 0.281

 < 0.001‡

67.169 \(\pm\) 14.334

0.321

  < 30

129 (24.855)

0.738 \(\pm\) 0.183

 

67.178 \(\pm\) 16.990

 

 ≥ 30

207 (39.884)

0.728 \(\pm\) 0.200

 

69.324 \(\pm\) 16.496

 

BMI,\(\mathrm{kg}/{\mathrm{m}}^{2}\)

  < 18.5

6 (1.156)

0.378 \(\pm\) 0.355

0.002

58.500 \(\pm\) 11.895

0.025

 18.5–24

142 (27.360)

0.727 \(\pm\) 0.214

 

70.824 \(\pm\) 15.804

 

 24–28

211 (40.655)

0.682 \(\pm\) 0.244

 

68.000 \(\pm\) 16.560

 

  > 28

160 (30.829)

0.673 \(\pm\) 0.230

 

65.950 \(\pm\) 14.861

 
  1. Abbreviations: EQ-5D-5L utility score, a single index ‘utility’ score representing the EQ-5D-5L health states, EQ-VAS score EQ visual analogue scale; sd, Standard Deviation
  2. +100 CNY equals approximately 14.9 USD (April 2019 exchange rate)
  3. ‡Comparisons of the EQ-5D-5L utility score distributions by age, smoking status, cardiovascular disease, total knee arthroplasty, or daily exercise were analyzed using the Welch's t-test (two groups) or the Welch's ANOVA (multiple groups), since their corresponding \(p\)-values of the Levene's test for homogeneity of variances are all < 0.05. All other differences among groups were analyzed with the Student's t-test (two groups) or Fisher's classic one-way ANOVA (multiple groups)