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Table 2 Internal responsiveness of HRQoL in improved and worsening patient groups

From: Responsiveness of the short-form health survey and the Parkinson’s disease questionnaire in patients with Parkinson’s disease

HRQoL domains

Improveda (n = 16)

Worseninga (n = 34)

Baseline mean (SD)

Follow-up mean (SD)

ES

SRM

p

Baseline mean (SD)

Follow-up mean (SD)

ES

SRM

p

SF-36

 Physical functioning

70.00 (25.36)

78.13 (23.09)

0.32

0.44

0.129

70.29 (23.39)

63.97 (20.55)

−0.27

−0.31

0.094

 Role-physical

53.13 (46.44)

56.25 (41.33)

0.07

0.07

0.832

44.85 (40.26)

39.71 (37.50)

−0.13

−0.16

0.379

 Bodily pain

74.25 (27.23)

72.19 (24.85)

−0.08

−0.15

0.611

73.44 (25.17)

67.91 (26.22)

−0.22

−0.26

0.061

 General health*

51.75 (15.64)

65.56 (20.03)

0.88

0.65

0.017

52.41 (20.42)

48.88 (21.14)

−0.17

−0.19

0.271

 Mental health

70.50 (19.09)

73.00 (17.44)

0.13

0.12

0.505

71.76 (23.88)

68.12 (20.62)

−0.15

−0.17

0.155

 Role-emotional

60.42 (40.77)

62.50 (29.50)

0.05

0.05

0.888

58.82 (42.69)

50.98 (41.22)

−0.18

−0.19

0.388

 Social functioning†

71.09 (29.13)

80.47 (21.39)

0.32

0.34

0.190

71.32 (24.72)

61.76 (31.07)

−0.39

−0.39

0.048

 Vitality†

61.88 (20.89)

61.56 (20.06)

−0.01

−0.02

0.813

60.15 (23.73)

52.35 (20.61)

−0.33

−0.40

0.035

 Total scores†

64.13 (22.65)

68.71 (18.71)

0.20

0.30

0.191

62.88 (21.54)

56.71 (19.81)

−0.29

−0.43

0.017

PDQ-39

 Mobility**

22.66 (24.60)

14.69 (18.97)

0.32

0.72

0.010

22.57 (23.82)

29.2 (24.52)

−0.28

−0.27

0.098

 ADL

17.45 (18.77)

12.76 (16.42)

0.25

0.43

0.113

15.32 (16.69)

18.26 (18.46)

−0.18

−0.16

0.211

 Emotional well-being†

10.68 (12.73)

9.64 (16.30)

0.08

0.12

0.159

18.14 (19.65)

22.67 (18.55)

−0.23

−0.26

0.035

 Stigma

13.28 (18.38)

7.81 (12.18)

0.30

0.27

0.236

20.59 (22.64)

23.53 (22.62)

−0.13

−0.17

0.154

 Social support††

8.59 (16.28)

7.03 (16.51)

0.10

0.09

0.932

4.78 (8.59)

15.07 (21.05)

−1.20

−0.51

0.001

 Cognitions

12.89 (14.34)

16.02 (16.61)

−0.22

−0.19

0.429

24.26 (20.46)

29.41 (15.58)

−0.25

−0.27

0.071

 Communication

6.25 (9.86)

10.94 (13.85)

−0.48

−0.34

0.172

11.03 (19.43)

20.59 (21.73)

−0.49

−0.55

0.003

 Bodily discomfort†

21.88 (20.16)

14.06 (14.82)

0.39

0.47

0.078

21.57 (20.73)

27.45 (24.41)

−0.28

−0.32

0.049

 SI††

14.21 (9.52)

11.62 (11.72)

0.27

0.37

0.074

17.28 (14.22)

23.28 (14.58)

−0.42

−0.55

0.004

  1. SF-36 36-item Short Form Health Survey, PDQ-39 39-item Parkinson’s Disease Questionnaire Single Index, ADL activities of daily living, SI summary index, SD standard deviation, ES effect size, SRM standardized response mean
  2. aThe minimal clinically important difference (MCID) of the Movement Disorder Society Revision of the Unified Parkinson’s Disease Rating Scale Part III was used to classify PD patients into improved and worsening groups
  3. *Significant differences between baseline and follow-up in the improved group by using Wilcoxon test, *p < 0.05, **p < 0.01
  4. †Significant differences between baseline and follow-up in the worsening group by using Wilcoxon test, † p < 0.05, †† p < 0.01
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Health and Quality of Life Outcomes

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