n | T0 | T4 | Δ (95% CI) | SRM (95% CI) | ES (95% CI) | |
---|---|---|---|---|---|---|
MHQ | ||||||
Benefit | 303 | 51.91 | 57.86 | 5.95 (2.75 to 9.15) | 0.21 (-1.70 to 3.12) | 0.29 (-1.61 to 2.21) |
No benefit | 116 | 49.34 | 49.14 | -0.2 (-3.46 to 3.06) | -0.01 (-2.98 to 2.96) | -0.02 (-2.98 to 2.95) |
Harm | 11 | 45.93 | 48.37 | 2.44 (-11.61 to 16.48) | 0.10 (-7.40 to 7.61) | 0.14 (-7.36 to 7.65) |
EQ-5D (utility) | ||||||
Benefit | 303 | 0.59 | 0.63 | 0.04 (0.00 to 0.08) | 0.11 (0.08 to 0.14) | 0.15 (0.13 to 0.18) |
No benefit | 116 | 0.59 | 0.57 | -0.02 (-0.09 to 0.05) | -0.05 (-0.09 to 0.00) | -0.07 (-0.12 to -0.02) |
Harm | 11 | 0.55 | 0.59 | 0.04 (-0.23 to 0.31) | 0.09 (-0.13 to 0.31) | 0.13 (-0.09 to 0.35) |
EQ-5D (VAS) | ||||||
Benefit | 303 | 68.92 | 71.99 | 3.07 (0.32 to 5.82) | 0.13 (-1.85 to 2.10) | 0.18 (-1.80 to 2.15) |
No benefit | 116 | 65.77 | 63.09 | -2.68 (-7.93 to 2.57) | -0.09 (-3.72 to 3.53) | -0.13 (-3.75 to 4.49) |
Harm | 11 | 61.18 | 61.81 | 0.63 (-18.12 to 19.38) | 0.02 (-15.19 to 15.23) | 0.03 (-15.18 to 15.23) |
SF-12 (PCS) | ||||||
Benefit | 303 | 34.02 | 35.27 | 1.25 (-0.64 to 3.14) | 0.07 (-1.16 to 1.32) | 0.11 (-1.14 to 1.35) |
No benefit | 116 | 32.85 | 33.59 | 0.74 (-1.95 to 3.43) | 0.05 (-1.94 to 2.04) | 0.07 (-1.92 to 2.06) |
Harm | 11 | 27.23 | 29.06 | 1.83 (-11.40 to 15.06) | 0.08 (-9.47 to 9.63) | 0.12 (-9.43 to 9.66) |
SF-12 (MCS) | ||||||
Benefit | 303 | 48.07 | 47.85 | -0.22 (-2.39 to 1.96) | -0.01 (-1.46 to 1.44) | -0.02 (-1.47 to 1.43) |
No benefit | 116 | 47.45 | 47.93 | 0.48 (-2.89 to 3.85) | 0.03 (-2.45 to 2.50) | 0.04 (-2.43 to 2.51) |
Harm | 11 | 35.9 | 33.66 | -2.24 (-19.75 to 15.27) | -0.08 (-12.62 to 12.46) | -0.11 (-12.64 to 12.43) |
SF-6D | ||||||
Benefit | 303 | 0.65 | 0.66 | 0.01 (-0.01 to 0.03) | 0.05 (0.03 to 0.06) | 0.06 (0.05 to 0.08) |
No benefit | 116 | 0.63 | 0.64 | 0.01 (-0.03 to 0.05) | 0.05 (0.02 to 0.08) | 0.07 (0.04 to 0.10) |
Harm | 11 | 0.61 | 0.52 | -0.09 (-0.24 to 0.06) | -0.36 (-0.45 to -0.27) | -0.51 (-0.06 to -0.04) |