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Table 7 Responsiveness of measures over time to perceived benefit/harm; baseline to 4 months

From: An empirical evaluation of the SF-12, SF-6D, EQ-5D and Michigan Hand Outcome Questionnaire in patients with rheumatoid arthritis of the hand

 

n

T0

T4

Δ (95% CI)

SRM (95% CI)

ES (95% CI)

MHQ

 Benefit

303

51.91

57.86

5.95 (2.75 to 9.15)

0.21 (-1.70 to 3.12)

0.29 (-1.61 to 2.21)

 No benefit

116

49.34

49.14

-0.2 (-3.46 to 3.06)

-0.01 (-2.98 to 2.96)

-0.02 (-2.98 to 2.95)

 Harm

11

45.93

48.37

2.44 (-11.61 to 16.48)

0.10 (-7.40 to 7.61)

0.14 (-7.36 to 7.65)

EQ-5D (utility)

 Benefit

303

0.59

0.63

0.04 (0.00 to 0.08)

0.11 (0.08 to 0.14)

0.15 (0.13 to 0.18)

 No benefit

116

0.59

0.57

-0.02 (-0.09 to 0.05)

-0.05 (-0.09 to 0.00)

-0.07 (-0.12 to -0.02)

 Harm

11

0.55

0.59

0.04 (-0.23 to 0.31)

0.09 (-0.13 to 0.31)

0.13 (-0.09 to 0.35)

EQ-5D (VAS)

 Benefit

303

68.92

71.99

3.07 (0.32 to 5.82)

0.13 (-1.85 to 2.10)

0.18 (-1.80 to 2.15)

 No benefit

116

65.77

63.09

-2.68 (-7.93 to 2.57)

-0.09 (-3.72 to 3.53)

-0.13 (-3.75 to 4.49)

 Harm

11

61.18

61.81

0.63 (-18.12 to 19.38)

0.02 (-15.19 to 15.23)

0.03 (-15.18 to 15.23)

SF-12 (PCS)

 Benefit

303

34.02

35.27

1.25 (-0.64 to 3.14)

0.07 (-1.16 to 1.32)

0.11 (-1.14 to 1.35)

 No benefit

116

32.85

33.59

0.74 (-1.95 to 3.43)

0.05 (-1.94 to 2.04)

0.07 (-1.92 to 2.06)

 Harm

11

27.23

29.06

1.83 (-11.40 to 15.06)

0.08 (-9.47 to 9.63)

0.12 (-9.43 to 9.66)

SF-12 (MCS)

 Benefit

303

48.07

47.85

-0.22 (-2.39 to 1.96)

-0.01 (-1.46 to 1.44)

-0.02 (-1.47 to 1.43)

 No benefit

116

47.45

47.93

0.48 (-2.89 to 3.85)

0.03 (-2.45 to 2.50)

0.04 (-2.43 to 2.51)

 Harm

11

35.9

33.66

-2.24 (-19.75 to 15.27)

-0.08 (-12.62 to 12.46)

-0.11 (-12.64 to 12.43)

SF-6D

 Benefit

303

0.65

0.66

0.01 (-0.01 to 0.03)

0.05 (0.03 to 0.06)

0.06 (0.05 to 0.08)

 No benefit

116

0.63

0.64

0.01 (-0.03 to 0.05)

0.05 (0.02 to 0.08)

0.07 (0.04 to 0.10)

 Harm

11

0.61

0.52

-0.09 (-0.24 to 0.06)

-0.36 (-0.45 to -0.27)

-0.51 (-0.06 to -0.04)