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Table 4 Univariate analysis and Multivariable logistic regression analysis models for PHS and MHS

From: Health-related quality of life and associated factors in people with HIV: an Irish cohort study

 

Good PHS (Total PHS score > 50)

Good MHS (Total MHS score > 50)

 

Univariate analysis

Multivariable analysis

Univariate analysis

Multivariable analysis

Variables

OR (95 % CI)

p

OR (95 % CI)

p

OR (95 % CI)

p

OR (95 % CI)

p

Age (years)

0.984 (0.96–1.01)

0.13

1.00 (0.97–1.03)

0.919

1.024 (1.00–1.05)

0.017

1.05 (1.02–1.08)

0.001

Gender

  Male

1.546 (1.04–2.30)

0.031

2.47 (1.22–4.98)

0.012

1.611 (1.11–2.34)

0.013

1.76 (0.96–3.24)

0.068

 Female (Ref)

–

–

–

–

–

–

–

–

Ethnicity

 Non-Caucasian

2.53 (1.57–4.09)

<0.001

3.55 (1.63–7.73)

0.001

1.23 (0.84–1.81)

0.295

2.11 (1.12–3.99)

0.021

 Caucasian (Ref)

–

–

–

–

–

–

–

–

Education

Higher education

3.581 (2.37–5.40)

<0.001

2.33 (1.32–4.12)

0.004

1.75 (1.23–2.48)

0.002

1.10 (0.68–1.80)

0.697

Lower education (Ref)

–

–

–

–

–

–

–

–

Employment

 Employed

5.524 (3.65–8.43)

<0.001

4.02 (2.27–7.14)

<0.001

3.327 (2.32–4.78)

<0.001

2.12 (1.28–3.50)

0.003

 Unemployed (Ref)

–

–

–

–

–

–

–

–

Living condition

 Lives with family

1.037 (0.71–1.52)

0.851

0.81 (0.45–1.47)

0.491

1.038 (0.73–1.48)

0.838

0.70 (0.42–1.16)

0.166

 Lives alone (Ref)

–

–

–

–

–

–

–

–

Sexual activity status

 Sexually active

2.626 (1.77–3.91)

<0.001

1.22 (0.70–2.11)

0.478

1.768 (1.22–2.57)

0.003

1.04 (0.63–1.71)

0.881

 Sexually not active (Ref)

–

–

–

–

–

–

–

–

Current use of illicit drugs

No

2.237 (1.37–3.66)

0.001

1.55 (0.76–3.16)

0.224

2.229 (1.36–3.66)

0.002

2.53 (1.31–4.89)

0.006

Yes (Ref)

–

–

–

–

–

–

–

–

Use of alcoholic drinks

 

 No

0.742 (0.47–1.18)

0.209

2.00 (1.01–3.98)

0.047

0.496 (1.36–3.66)

0.002

0.69 (0.39–1.25)

0.223

 Yes (Ref)

–

–

–

–

–

–

–

–

HIV transmission mode

 MSM

1.96 (1.29–2.99)

0.002

0.95 (0.47–1.92)

0.89

1.678 (1.16–2.43)

0.006

0.69 (0.38–1.26)

0.227

 Not MSM (Ref)

–

–

–

–

–

–

–

–

Time since HIV diagnosed

0.956 (0.93–0.99)

0.004

1.01 (0.97–1.06)

0.579

1 (0.97–1.03)

0.987

1.03 (0.98–1.07)

0.258

HIV symptoms

 No

5.221 (3.20–8.53)

<0.001

3.49 (1.77–6.89)

<0.001

5.294 (3.042–9.21)

<0.001

3.56 (1.79–7.10)

<0.001

 Yes (Ref)

–

–

–

–

–

–

–

–

Current ART status

 No

1.578 (.83–3.02)

0.167

3.11 (0.96–10.11)

0.059

1.316 (0.76–2.29)

0.33

2.47 (0.95–6.42)

0.063

 Yes (Ref)

–

–

–

–

–

–

–

–

Recent CD4 level

  > 350cells/mm3

2.029 (1.26–3.26)

0.003

1.22 (0.63–2.39)

0.558

2.166 (1.35–3.48)

0.001

1.54 (0.83–2.86)

0.17

  ≤ 350cells/mm3 (Ref)

–

–

–

–

–

–

–

–

Recent viral load

  < 40 copies/ml

1.471 (0.94–2.30)

0.089

1.65 (0.72–3.79)

0.24

1.511 (0.99–2.31)

0.058

1.73 (0.81–3.72)

0.158

  ≥ 40 copies/ml (Ref)

–

–

–

–

–

–

–

–

HIV complications

 No

3.097 (1.90–5.04)

<0.001

1.97 (1.01–3.82)

0.046

1.615 (1.00–2.61)

0.051

1.13 (0.60–2.12)

0.708

 Yes (Ref)

–

–

–

–

–

–

–

–

Co-morbidities

 No

3.873 (2.57–5.85)

<0.001

2.29 (1.29–4.07)

0.004

2.529 (1.78–3.60)

<0.001

2.46 (1.50–4.02)

<0.001

 Yes (Ref)

–

–

–

–

–

–

–

–

BMI (kg/m 2 )

1.014 (0.97–1.06)

0.533

0.97 (0.90–1.03)

0.283

0.982 (0.95–1.02)

0.369

0.92 (0.86–0.97)

0.004

Risk of malnutrition

 Low risk

3.069 (1.78–5.31)

<0.001

1.73 (0.75–3.97)

0.198

2.48 (1.41–4.38)

0.002

2.25 (1.02–4.97)

0.045

 High risk (Ref)

–

–

–

–

–

–

–

–

Overall Social Support

1.022 (.02–1.03)

<0.001

1.03 (1.02–1.04)

<0.001

1.025 (1.02–1.03)

<0.001

1.03 (1.02–1.04)

<0.001

Disclosure issues

0.996 (0.99–1.00)

0.321

1.00 (0.99–1.01)

0.608

1.002 (1.00–1.01)

0.577

1.01 (1.00–1.02)

0.105

  1. Abbreviations: OR odds ratio, CI confidence interval, PHS physical health summary score, MHS mental health summary score
  2. The bolded p-values correspond to the variables that are significant in both the univariate and multivariable analyses