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Table 6 Regression algorithms for converting NIHSS data into AQoL scores

From: Can we derive an 'exchange rate' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique

Model

Predictor

β

SE

t

Sig.

NIHSS Index

     

All stroke

(Constant)

0.4639

0.0044

104.97

0.000

 

NIHSS

0.0024

0.0020

1.20

0.230

 

NIHSS*NIHSS

-0.0000

0.0000

-1.22

0.224

 

0.7856

 

F849,1718 = 8.45

0.000

  

Obs = 1302

Ids = 705

F2,595 = 1.35

0.259

   

R2 within = 0.00

R2 between = 0.17

R2 overall = 0.12

NIHSS = 0–5

(Constant)

0.4754

0.0066

72.07

0.000

 

NIHSS

0.0802

0.0178

4.52

0.000

 

NIHSS*NIHSS

-0.0170

0.0046

-3.68

0.000

 

0.7955

 

F652,540 = 6.27

0.000

  

Obs = 1195

Ids = 653

F2,540 = 11.41

0.000

   

R2 within = 0.04

R2 between = 0.00

R2 overall = 0.00

NIHSS ≥ 6

(Constant)

0.2882

0.0874

3.30

0.001

 

NIHSS

-0.0247

0.0133

-1.85

0.064

 

NIHSS*NIHSS

0.0005

0.0004

1.19

0.234

 

0.7680

-

-

-

  

Obs = 103

Ids = 88

Wald χ2 = 11.58

0.003

   

R2 within = 0.00

R2 between = 0.12

R2 overall = 0.12

NIHSS Item

     

All stroke

(Constant)

0.4499

0.0059

76.81

0.000

 

Visual fields

-0.0475

0.0232

-2.05

4.53

 

Facial weakness

0.0909

0.0201

4.53

0.000

 

0.8103

 

F704,595 = 6.86

0.000

  

Obs = 1302

Ids = 705

F2,595 = 10.89

0.000

   

R2 within = 0.04

R2 between = 0.03

R2 overall = 0.01

NIHSS = 0–5

(Constant)

0.4810

0.0055

88.15

0.000

 

Facial weakness

0.0984

0.0232

4.24

0.000

 

Limb ataxia

0.0630

0.0273

2.31

0.021

 

0.7984

 

F652,540 = 6.67

0.000

  

Obs = 1195

Ids = 653

F2,540 = 12.42

0.000

   

R2 within = 0.04

R2 between = 0.01

R2 overall = 0.01

NIHSS ≥ 6

(Constant)

0.0732

0.0496

1.48

0.191

 

Consciousness

-0.3052

0.0572

-5.34

0.002

 

Eye movements

0.3073

0.0846

3.63

0.011

 

Facial weakness

-0.1033

0.0263

-3.93

0.008

 

Motor – Left arm

0.0760

0.0208

3.65

0.011

 

Motor – Right leg

-0.3157

0.0364

-8.66

0.000

 

Motor – Left leg

0.2980

0.0415

7.18

0.000

 

Sensory

-0.1340

0.0310

-4.33

0.005

 

Language

0.1336

0.0319

4.19

0.006

 

Extinction/Inattention

-0.1198

0.0270

-4.44

0.004

 

0.6653

 

F87,6 = 32.07

0.000

  

Obs = 103

Ids = 88

F9,6 = 10.36

0.005

   

R2 within = 0.94

R2 between = 0.05

R2 overall = 0.05