Author(s) | Year | Sample | HRQOL measure(s) | Results* |
---|---|---|---|---|
Pater and Loeb [11] | 1982 | 651 bronchogenic carcinoma | Symptomatic history, performance status, weight loss and age | Weight loss and performance status were significantly affected survival. |
Kaasa et al. [14] | 1989 | 102 inoperable non-small-cell, limited disease | Psychological well-being + disease-related symptoms + personal functioning + everyday activity | General symptoms and psychological well-being were the best predictive value for survival. |
Ganz et al. [22] | 1991 | 40 advanced metastatic lung cancer | FLI-C | A statistically significant relationship was observed between initial patient-rated QOL and subsequent survival. |
Ruckdeschel et al. [23] | 1994 | 438 lung cancer | FLI-C | Total FLI-C score was significant predictor of survival. |
Loprinzi et al. [24] | 1994 | 1,115 advanced colorectal or lung cancers | A designed patient-completed questionnaire | Patients' assessment of their own performance status and nutritional factors such as appetite, caloric intake, or overall food intake were prognostic of survival. |
Buccheri et al. [25] | 1995 | 128 Lung cancer | TIQ | The self-estimated difficulty at work and doing housework were significant independent prognostic determinants of survival. |
Buccheri et al. [26] | 1998 | 133 Lung cancer | SDS | Depression was associated with survival. Diverse SDS subscales were associated with survival. |
Herndon et al. [27] | 1999 | 206 advanced non-small-cell lung cancer | EORTC QLQ-C30 + Duke-UNC Social Support Scale | Pain was a significant predictor of survival but overall QOL was not. |
Langendijk et al. [28] | 2000 | 198 inoperable non-small-cell lung cancer | EORTC QLQ-C30 | Global QOL was a strong prognostic factor of survival. |
Burrows et al. [29] | 2000 | 85 recurrent symptomatic malignant pleural effusions | KPS | Only the KPS score (score ≥ 70) at the time of thoracoscopy was predictive of survival. Pleural fluid pH, pleural fluid glucose, and EPC scores were not as reliable as initially reported. |
Montazeri et al. [30] | 2001 | 129 lung cancer (small and non-small-cell) | NHP + EORTC QLQ-C30 + EORTC QLQ-LC13 | Baseline global QOL was most significant predictor of the length of survival. |
Auchter et al. [31] | 2001 | 30 non-small cell lung cancer | FACT-L (TOI) | The change in TOI score was not associated with survival. A trend was noted for shorter survival with the largest negative change in TOI score. |
Moinpour et al. [32] | 2002 | 222 advanced non-small-cell | FACT-L | Total FACT-L score was predictor of survival. |
Nakahara et al. [33] | 2002 | 179 advanced small- and non-small cell lung cancer | Tokyo University Egogram (measure for mental state) | Mental state was prognostic of survival. |
Naughton et al. [34] | 2002 | 70 small-cell lung cancer | EORTC QLQ-C30 + CES-D + MOS Social Support Questionnaire + a sleep quality scale | Higher depressive symptoms were borderline significant in predicting decreased survival. |
Eton et al. [35] | 2003 | 573 advanced non-small-cell lung cancer | FACT-L + TOI | Baseline physical well-being and TOI scores predicted either survival duration or disease progression respectively. |
Dharma-Wardene et al. [36] | 2004 | 44 advanced lung cancer | FACT-G | Baseline FACT-G total score was significantly associated with survival. |
Nowak et al. [37] | 2004 | 53 pleural mesothelomia | EORTC QLQ-C30 + EORTC QLQ-LC13 | Functional domains and symptom scales (fatigue and pain) demonstrated predictive validity for survival. |
Maione et al. [38] | 2005 | 566 advanced non-small-cell lung cancer | ADL + IADL + EORTC QOL-C30 (global QOL) | Baseline global QOL and IADL were significant prognostic factors for overall survival. |
Brown et al. [39] | 2005 | 273 non-small-cell lung cancer | EORTC QLQ-C30 + EORTC QLQ-LC17 + DDC | Global QOL, role functioning, fatigue, appetite loss and constipation were prognostic indicators of survival. |
Martins et al. [40] | 2005 | 41 locally advanced or metastatic lung cancer | LCSS | Patients' scores on the LCSS appetite and fatigue subscales were independent predictors of survival. |
Efficace et al. [41] | 2006 | 391 advanced non-small-cell lung cancer | EORTC QLQ-C30 + EORTC QLQ-LC13 | Pain, and dysphagia were significant prognostic factors for survival. |
Sundstrom et al. [42] | 2006 | 301 stag III non-small-cell lung cancer | EORTC QLQ-C30 | Appetite loss was the most significant prognostic factor of survival. |
Bottomley et al. [43] | 2007 | 250 malignant pleural mesothelioma | EORTC QLQ-C30 + EORTC QLQ-LC13 | Pain, and appetite loss were independent prognostic indicators of survival. |
Fielding and Wong [44] | 2007 | 534 liver and lung cancers | FACT-G | Global QOL scores did not predict survival in liver and lung cancer. Physical well-being and appetite predicted survival in lung cancer. |
Jacot et al. [45] | 2008 | 301 non-small-cell lung cancer | LCSS | Pretreatment LCSS global symptoms score was independent determinant of overall survival. |