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Table 2 Baseline demographic and clinical characteristics of the enrolled population

From: Improvements in patient-reported outcomes with apremilast, an oral phosphodiesterase 4 inhibitor, in the treatment of moderate to severe psoriasis: results from a phase IIb randomized, controlled study

Characteristic

Placebo (n=88)

Apremilast BID

Total (N=352)

  

10 mg (n=89)

20 mg (n=87)

30 mg (n=88)

 

Age (years)

44.1 ± 13.7

44.4 ± 14.0

44.6 ± 12.6

44.1 ± 14.7

44.3 ± 13.7

Male

53 (60.2)

63 (70.8)

55 (63.2)

50 (56.8)

221 (62.8)

Race

     

   White

83 (94.3)

82 (92.1)

82 (94.3)

80 (90.9)

327 (92.9)

   Black

1 (1.1)

2 (2.2)

1 (1.1)

2 (2.3)

6 (1.7)

   Asian

4 (4.5)

3 (3.4)

2 (2.3)

4 (4.5)

13 (3.7)

   Other

0 (0.0)

2 (2.2)

2 (2.3)

2 (2.3)

6 (1.7)

Height (cm)

171.2 ± 8.6

171.5 ± 10.2

171.7 ± 9.6

171.2 ± 10.7

171.5 ± 9.6

Weight (kg)

90.3 ± 21.4

95.7 ± 23.2

89.9 ± 20.2

91.2 ± 23.1

91.8 ± 22.0

BMI (kg/m2)

30.8 ± 6.7

32.5 ± 7.4

30.4 ± 6.2

31.1 ± 7.8

31.2 ± 7.1

Total PASI score

18.1 ± 5.7

18.1 ± 6.3

18.5 ± 7.3

19.1 ± 7.1

18.5 ± 6.6

BSA

21.0 ± 11.2

21.3 ± 11.4

20.7 ± 12.4

25.0 ± 15.4

22.0 ± 12.8

+ History PsA

17 (19.3)

20 (22.5)

16 (18.4)

21 (23.9)

74 (21.0)

Plaque psoriasis history (years)

19.6 ± 11.6

18.0 ± 12.4

19.2 ± 12.2

19.2 ± 12.0

19.0 ± 12.0

Previous systemic therapy for psoriasis

39 (44.3)

47 (52.8)

43 (49.4)

47 (53.4)

176 (50.0)

  1. Values are mean ± SD or n (%). BMI, body mass index; BSA, body surface area; PASI, Psoriasis Area and Severity Index; PsA, psoriatic arthritis.