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Table 3 Results of ‘known group’ comparisons

From: A review of the psychometric performance of the EQ-5D in people with urinary incontinence

Author(s), Year

Groups defined as

Instrument

Direction of change consistent across groups and consistent with clinical expectation?

Difference between groups statistically significant?

Haywood et al, 2008 [7]

Number of episodes at baseline:

   

EQ-5D

Yes‡

No at p=0.01

Not at all

SSI

Yes

Yes, p<0.01

A few days

I-QoL index

Yes

Yes, p<0.01

Half the week

I-QoL domains

Mixed†

Yes, p<0.01

Most days

   

Every day

   

Tincello et al, 2010 [19]

Episode frequency:

   

<=7 per week

EQ-5D

Yes

Yes, p<0.0001

7 to 13 per week

>=14 per week

Monz et al, 2005 [13]

Severity (reported for each subtype)

   

Slight

EQ-5D

Yes

Not reported

Moderate

EQ-VAS

Yes

Not reported

Severe

Mean I-QoL

Yes

Not reported

Very severe

I-QoL domains

Yes

Not reported

Hawthorne, 2009 [2]

Continence status:

   

a) None

EQ-5D

Yes

Yes, p<0.0001

b) Slight/mild

SF-6D

Yes

Yes, p<0.0001

c) Moderate

AQoL

Yes

Yes, p<0.0001

d) Severe

AQoL-8

Yes

Yes, p<0.0001

Currie et al, 2006 [10]

Type of incontinence:

   

General

EQ-5D

Stress<general<none*

Not reported

Stress

SF-36

As for EQ-5D

As for EQ-5D

None

   

Monz et al, 2005 [13]

Subtype (reported for each severity category):

   

EQ-5D

Stress>urge>mixed*

Not reported

EQ-VAS

As for EQ-5D (except when severity slight)

Not reported

Stress

Mean I-QoL

As for EQ-5D

Not reported

Urge

I-QoL domains

No consistent pattern across all domains

Not reported

Mixed

Tincello et al, 2010 [19]

UI subtype:

   

Mixed

EQ-5D

Stress>urge>mixed*

Yes, p<0.0001

Pure stress

Pure urge

  1. †Yes for 2/3 domains, ‡Same mean for two least severe domains, *Unclear which type of incontinence is expected to have lower utility. VAS=visual analogue scale, I-QOL=Incontinence specific Quality of life Questionnaire, SSI= symptom severity index, SF-36=Medical outcomes study 36-Item Short-Form Health Survey, SF-6D= Classification for describing health derived from a selection of SF-36 items, AQoL= Assessment of Quality of Life.