Development of a disease-specific quality of life questionnaire for adult patients with hereditary angioedema due to C1 inhibitor deficiency (HAE-QoL): Spanish multi-centre research project

Table 2 Severity Score (over the last year)

Severity Score	Criteria
ASYMPTOMATIC	No angioedema episodes and no long term prophylactic treatment.
MILD	No life-threatening angioedema episodes, no long term prophylactic treatment and ≤ 6 episodes/year.
MODERATE	No life-threatening angioedema episodes and ≤ 12 episodes/year with long term prophylactic treatment (exclude maintenance treatment with pdhC1INH) or > 6 episodes/year without long term prophylactic treatment.
SEVERE	Life-threatening angioedema episode and/or > 12 episodes/year with long term prophylactic treatment and/or maintenance treatment with pdhC1INH.

ISSN: 1477-7525