Table 2 Thematic Content Analysis of Factors Relevant to Patients' Satisfaction With Their Medication Use

• The eye pressure readings are the only way one can tell

• Some report improvements in their vision, including:

   Ability to read (small print) without glasses

   Vision is clearer/not as blurred or cloudy

   Distance vision is clearer

   Able to see better at night

• Burning, Itching, Grittiness/Sandiness, Dryness, Tearing of eyes

• Redness of eye, Darkening of iris of eyes

• Swelling, Crustiness, Stickiness of eyelids

• Visual Changes (e.g., "clear ropes" in eyes, loss of center of vision, sensitivity to light)

• Systemic affects associated with allergenic reaction or use of oral treatments: shortness of breath, restlessness/inability to sleep, excessive perspiration, low energy, migraines

• Discomfort putting things in eyes

• Strong "blink reflex" making it difficult to instill the drops

• Difficulty learning to instill drops

• Miss the eye when administering the medicine

• Unable to feel whether a drop has gone into their eye

• Inadvertently dispense more than one drop, or dispense just one more to be sure

• Require assistance if elderly or physically impaired (e.g., have Parkinson's)

• Trouble remembering to use the medicine, particularly on trips or vacations

• Instillation twice a day, this is less convenient than once

• Frustration with the daily dosing and, as a result, sometimes not taking their medicine

• More inconvenient to administer evening than morning doses, sometimes too tired in evening

• Delay taking medication in evening till returning home

• Difficult to tell when their medicine is about to run out