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  1. The aim was to investigate HRQoL and psychosocial function among patients with carcinoid tumours, longitudinally and prospectively, and to compare HRQoL among patients with carcinoid tumours to that of the Swe...

    Authors: Camilla Fröjd, Gunnel Larsson, Claudia Lampic and Louise von Essen

    Citation: Health and Quality of Life Outcomes 2007 5:18

    Content type: Research

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  2. Co-morbidity is a powerful predictor of health care outcomes and costs, as well as an important cofounder in epidemiologic studies. The effect of co-morbidities is generally related to mortality or complicatio...

    Authors: Ulla Tuominen, Marja Blom, Johanna Hirvonen, Seppo Seitsalo, Matti Lehto, Pekka Paavolainen, Kalevi Hietanieni, Pekka Rissanen and Harri Sintonen

    Citation: Health and Quality of Life Outcomes 2007 5:16

    Content type: Research

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  3. Subjective measures involving clinician ratings or patient self-assessments have become recognised as an important tool for the assessment of health outcome. The value of a health outcome measure is usually as...

    Authors: Beth Pollard, Marie Johnston and Diane Dixon

    Citation: Health and Quality of Life Outcomes 2007 5:14

    Content type: Review

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  4. A large number of fatigue scales exist and there is no consensus on which fatigue measuring scales that are most appropriate for use in assessment of fatigue in different diseases. We aimed to describe the use...

    Authors: Niels Henrik Hjollund, Johan Hviid Andersen and Per Bech

    Citation: Health and Quality of Life Outcomes 2007 5:12

    Content type: Review

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  5. No validated disease-specific measures are available to assess health-related quality of life (HRQoL) in adult subjects with immune thrombocytopenic purpura (ITP). Therefore, we sought to develop and validate ...

    Authors: Susan D Mathias, James B Bussel, James N George, Robert McMillan, Gary J Okano and Janet L Nichol

    Citation: Health and Quality of Life Outcomes 2007 5:11

    Content type: Research

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  6. To determine physical and psychosocial well-being of adolescents with type 1 diabetes by self-report and parent report and to explore associations with glycemic control and other clinical and socio-demographic...

    Authors: Maartje de Wit, Henriette A Delemarre-van de Waal, Jan Alle Bokma, Krijn Haasnoot, Mieke C Houdijk, Reinoud J Gemke and Frank J Snoek

    Citation: Health and Quality of Life Outcomes 2007 5:10

    Content type: Research

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  7. Fibromyalgia is a chronic health condition characterized by widespread musculoskeletal pain, multiple tender points on physical examination, generalized muscular aching, stiffness, fatigue, nonrestorative slee...

    Authors: James W Varni, Tasha M Burwinkle, Christine A Limbers and Ilona S Szer

    Citation: Health and Quality of Life Outcomes 2007 5:9

    Content type: Research

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  8. Successfully managing diabetes is a complex process that includes addressing issues of drug efficacy, safety and treatment satisfaction. Additionally, the combined impact of patient/disease characteristics and...

    Authors: Meryl Brod, David Cobden, Morten Lammert, Donald Bushnell and Philip Raskin

    Citation: Health and Quality of Life Outcomes 2007 5:8

    Content type: Research

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  9. The Ankylosing Spondylitis Quality of Life (ASQOL) questionnaire is a unidimensional, disease-specific measure developed in the UK and the Netherlands. This study describes its adaptation into other languages.

    Authors: Lynda C Doward, Stephen P McKenna, David M Meads, James Twiss, Dennis Revicki, Robert L Wong and Michelle P Luo

    Citation: Health and Quality of Life Outcomes 2007 5:7

    Content type: Research

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  10. Dental disease and treatment experience can negatively affect the oral health related quality of life (OHRQL) of preschool aged children and their caregivers. Currently no valid and reliable instrument is avai...

    Authors: Bhavna Talekar Pahel, R Gary Rozier and Gary D Slade

    Citation: Health and Quality of Life Outcomes 2007 5:6

    Content type: Research

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  11. Health-related quality of life (HR-QOL) is a relevant and quantifiable outcome of care. We implemented HR-QOL assessment at all primary care visits at UCSD Owen Clinic using EQ-5D. The study aim was to estimat...

    Authors: William C Mathews and Susanne May

    Citation: Health and Quality of Life Outcomes 2007 5:5

    Content type: Research

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  12. Quality of life (QoL) outcomes are useful in the assessment of physical, mental and social well-being and for informed healthcare decision making. However, few studies have evaluated QoL issues among Asian chi...

    Authors: Hwee-Lin Wee, Ulrike Ravens-Sieberer, Michael Erhart and Shu-Chuen Li

    Citation: Health and Quality of Life Outcomes 2007 5:4

    Content type: Research

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  13. The last three decades have seen a dramatic rise in the implementation of screening programmes for cancer in industrialised countries. However, in contrast to screening for infectious diseases, most cancer scr...

    Authors: John Brodersen, Stephen P McKenna, Lynda C Doward and Hanne Thorsen

    Citation: Health and Quality of Life Outcomes 2007 5:3

    Content type: Commentary

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  14. Health-related quality of life (HRQOL) measurement has emerged as an important health outcome in clinical trials, clinical practice improvement strategies, and healthcare services research and evaluation. Whil...

    Authors: James W Varni, Christine A Limbers and Tasha M Burwinkle

    Citation: Health and Quality of Life Outcomes 2007 5:2

    Content type: Research

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  15. The last decade has evidenced a dramatic increase in the development and utilization of pediatric health-related quality of life (HRQOL) measures in an effort to improve pediatric patient health and well-being...

    Authors: James W Varni, Christine A Limbers and Tasha M Burwinkle

    Citation: Health and Quality of Life Outcomes 2007 5:1

    Content type: Research

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  16. Interferon-beta (IFN-β) shows beneficial effect on the course of multiple sclerosis (MS), nevertheless its route and frequency of administration and side effects might impact negatively the quality of life (Qo...

    Authors: Isabella Laura Simone, Antonia Ceccarelli, Carla Tortorella, Alessandra Bellacosa, Fabio Pellegrini, Immacolata Plasmati, Maria Fara De Caro, Mariangela Lopez, Francesco Girolamo and Paolo Livrea

    Citation: Health and Quality of Life Outcomes 2006 4:96

    Content type: Research

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  17. Although non-communicable and chronic disease now accounts for 47% of the global burden of disease, little is known of the everyday experiences and social aspects of disability and disablement in middle and lo...

    Authors: RoseAnne Misajon, Lenore Manderson, Julie F Pallant, Zaliha Omar, Elizabeth Bennett and Rameezan Begam Abdul Rahim

    Citation: Health and Quality of Life Outcomes 2006 4:95

    Content type: Research

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  18. Combining outcomes and the use of standardized effect measures such as effect size and standardized response mean across instruments allows more comprehensive meta-analyses and should avoid selection bias. How...

    Authors: Milo A Puhan, Irene Soesilo, Gordon H Guyatt and Holger J Schünemann

    Citation: Health and Quality of Life Outcomes 2006 4:94

    Content type: Research

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  19. To characterize ease in discussing death (EID) and its influence on health valuation in a multi-ethnic Asian population and to determine the acceptability of various descriptors of death and "pits"/"all-worst"...

    Authors: Hwee-Lin Wee, Shu-Chuen Li, Feng Xie, Xu-Hao Zhang, Nan Luo, Yin-Bun Cheung, David Machin, Kok-Yong Fong and Julian Thumboo

    Citation: Health and Quality of Life Outcomes 2006 4:93

    Content type: Research

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  20. This paper evaluates psychometric properties of a recently developed measure focusing on the health-related quality of life (HRQL) of long-term cancer survivors, the Quality of Life in Adult Survivors scale (Q...

    Authors: Nancy E Avis, Edward Ip and Kristie Long Foley

    Citation: Health and Quality of Life Outcomes 2006 4:92

    Content type: Research

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  21. There is a paucity of research about health-related quality of life (HRQL) among adolescents, as studies have to a large extent focused on adults. The main aim was to provide information for future studies in ...

    Authors: Anna Jörngården, Lena Wettergen and Louise von Essen

    Citation: Health and Quality of Life Outcomes 2006 4:91

    Content type: Research

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  22. Responsiveness, or sensitivity to clinical change, is an important consideration in selection of a health-related quality of life (HRQL) measure for trials or clinical applications. Many approaches can be used...

    Authors: Dean T Eurich, Jeffrey A Johnson, Kimberly J Reid and John A Spertus

    Citation: Health and Quality of Life Outcomes 2006 4:89

    Content type: Research

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  23. The PGWBI is a 22-item health-related Quality of Life (HRQoL) questionnaire developed in US which produces a self-perceived evaluation of psychological well-being expressed by a summary score. The PGWBI has be...

    Authors: Enzo Grossi, Nicola Groth, Paola Mosconi, Renata Cerutti, Fabio Pace, Angelo Compare and Giovanni Apolone

    Citation: Health and Quality of Life Outcomes 2006 4:88

    Content type: Research

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  24. To determine the clinimetric properties of two questionnaires assessing symptoms (Symptom Severity Scale) and physical functioning (hand and finger function subscale of the AIMS2) in a Dutch primary care popul...

    Authors: Marinda N Spies-Dorgelo, Caroline B Terwee, Wim AB Stalman and Daniëlle AWM van der Windt

    Citation: Health and Quality of Life Outcomes 2006 4:87

    Content type: Research

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  25. Recent research has suggested that chronic dry mouth affects the day-to-day lives of older people living in institutions. The condition has usually been considered to be a feature of old age, but recent work b...

    Authors: W Murray Thomson, Herenia P Lawrence, Jonathan M Broadbent and Richie Poulton

    Citation: Health and Quality of Life Outcomes 2006 4:86

    Content type: Research

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  26. Research on quality and satisfaction with care during palliative chemotherapy in oncology patients has been limited. The objective was to assess the association between patient's satisfaction with care and sym...

    Authors: Vivian E von Gruenigen, Jessica R Hutchins, Anne Marie Reidy, Heidi E Gibbons, Barbara J Daly, Elisa M Eldermire and Nancy L Fusco

    Citation: Health and Quality of Life Outcomes 2006 4:84

    Content type: Research

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  27. The aims of the study were to assess the impact of both positive (PA) and negative affect (NA) on self-reported oral health-related quality of life and to determine the effect of including affectivity on the r...

    Authors: David S Brennan, Kiran A Singh, A John Spencer and Kaye F Roberts-Thomson

    Citation: Health and Quality of Life Outcomes 2006 4:83

    Content type: Research

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  28. Screening asymptomatic individuals for neoplasia can have adverse consequences on quality of life. Colon cancer screening is widespread but the quality of life (QOL) consequences are unknown. This study determ...

    Authors: Doug Taupin, Sharon L Chambers, Mike Corbett and Bruce Shadbolt

    Citation: Health and Quality of Life Outcomes 2006 4:82

    Content type: Research

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  29. In Canada, the incidence of Fetal Alcohol Spectrum Disorder (FASD) has been estimated to be 1 in 100 live births. Caused by prenatal exposure to alcohol, FASD is the leading cause of neuro-developmental disabi...

    Authors: Brenda C Stade, Bonnie Stevens, Wendy J Ungar, Joseph Beyene and Gideon Koren

    Citation: Health and Quality of Life Outcomes 2006 4:81

    Content type: Research

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  30. Patient-reported measures can be used to examine whether drug differences other than clinical efficacy have an impact on outcomes that may be important to patients. Although exenatide and insulin glargine appe...

    Authors: Kristina Secnik Boye, Louis S Matza, Alan Oglesby, Karen Malley, Sunny Kim, Risa P Hayes and Robert Brodows

    Citation: Health and Quality of Life Outcomes 2006 4:80

    Content type: Research

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  31. The SF-36 has been used in a number of previous studies that have investigated the health status of childhood cancer survivors, but it never has been evaluated regarding data quality, scaling assumptions, and ...

    Authors: Raoul C Reulen, Maurice P Zeegers, Crispin Jenkinson, Emma R Lancashire, David L Winter, Meriel E Jenney and Mike M Hawkins

    Citation: Health and Quality of Life Outcomes 2006 4:77

    Content type: Research

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  32. Investigations of the structure of psychological well-being items are useful for advancing knowledge of what dimensions define psychological well-being in practice. Ryff has proposed a multidimensional model o...

    Authors: Rosemary A Abbott, George B Ploubidis, Felicia A Huppert, Diana Kuh, Michael EJ Wadsworth and Tim J Croudace

    Citation: Health and Quality of Life Outcomes 2006 4:76

    Content type: Research

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  33. The PedsQL™ Present Functioning Visual Analogue Scales (PedsQL™ VAS) were designed as an ecological momentary assessment (EMA) instrument to rapidly measure present or at-the-moment functioning in children and...

    Authors: Sandra A Sherman, Sarajane Eisen, Tasha M Burwinkle and James W Varni

    Citation: Health and Quality of Life Outcomes 2006 4:75

    Content type: Research

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  34. If decisions on health care spending are to be as rational and objective as possible, knowledge on cost-effectiveness of routine care is essential. Our aim, therefore, was to evaluate the cost-utility of routi...

    Authors: Pirjo Räsänen, Kari Krootila, Harri Sintonen, Tiina Leivo, Anna-Maija Koivisto, Olli-Pekka Ryynänen, Marja Blom and Risto P Roine

    Citation: Health and Quality of Life Outcomes 2006 4:74

    Content type: Research

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  35. To assess the literature for the impact of iron overload and infusion Iron Chelation Therapy (ICT) on patients' quality of life (QoL), and the availability of QoL instruments for patients undergoing infusion I...

    Authors: Linda Abetz, Jean-Francois Baladi, Paula Jones and Diana Rofail

    Citation: Health and Quality of Life Outcomes 2006 4:73

    Content type: Research

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  36. The influence of gender on the expression of COPD has received limited attention. Quality of Life (QoL) has become an important outcome in COPD patients. The aim of our study was to explore factors contributin...

    Authors: Juan P de Torres, Ciro Casanova, Concepción Hernández, Juan Abreu, Angela Montejo de Garcini, Armando Aguirre-Jaime and Bartolome R Celli

    Citation: Health and Quality of Life Outcomes 2006 4:72

    Content type: Research

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  37. Patient-reported outcome (PROs) measures are being used more frequently in investigational studies of treatments for moderate to severe plaque psoriasis. The objective of this study was to examine the relation...

    Authors: Richard Shikiar, Mary Kaye Willian, Martin M Okun, Christine S Thompson and Dennis A Revicki

    Citation: Health and Quality of Life Outcomes 2006 4:71

    Content type: Research

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  38. Patient reported outcomes provide the patient's perspective on the effectiveness of treatment. The draft Food and Drug Administration guidance on patient reported outcomes for labeling and promotional claims r...

    Authors: Dennis A Revicki, David Cella, Ron D Hays, Jeff A Sloan, William R Lenderking and Neil K Aaronson

    Citation: Health and Quality of Life Outcomes 2006 4:70

    Content type: Commentary

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  39. The evaluation and use of patient reported outcome (PRO) measures requires detailed understanding of the meaning of the outcome of interest. The Food and Drug Administration (FDA) recently presented its draft ...

    Authors: Jan L Brożek, Gordon H Guyatt and Holger J Schünemann

    Citation: Health and Quality of Life Outcomes 2006 4:69

    Content type: Commentary

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  40. Our objective was to test a brief, symptom index for advanced renal cell carcinoma, a disease affecting over 38,000 Americans each year and often diagnosed in late stages.

    Authors: David T Eton, David Cella, Jennifer Bacik and Robert J Motzer

    Citation: Health and Quality of Life Outcomes 2006 4:68

    Content type: Research

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  41. The purpose of this review was to: (1) locate all exercise treatment studies of fibromyalgia (FM) patients from 1988 through 2005, (2) present in tabular format the key details of each study and (3) to provide...

    Authors: Kim Dupree Jones, Dianne Adams, Kerri Winters-Stone and Carol S Burckhardt

    Citation: Health and Quality of Life Outcomes 2006 4:67

    Content type: Review

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  42. Measuring health-related quality of life (HRQOL) is important in arthritis and the SF-36v2 is the current state-of-the-art. It is only emerging how well the Centers for Disease Control and Prevention (CDC) HRQ...

    Authors: Thelma Mielenz, Elizabeth Jackson, Shannon Currey, Robert DeVellis and Leigh F Callahan

    Citation: Health and Quality of Life Outcomes 2006 4:66

    Content type: Research

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