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  1. Chronic liver diseases (CLDs) are progressive disorder which has a significant impact on the well-being of patients and leads to significant morbidity. CLDs are characterized by disturbances in physical, psych...

    Authors: Farkhondeh Sharif, Sadrollah Mohebbi, Hamid-Reza Tabatabaee, Mehdi Saberi-Firoozi and Sakineh Gholamzadeh

    Citation: Health and Quality of Life Outcomes 2005 3:81

    Content type: Research

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  2. Previous studies have evaluated the individual effects of acute myocardial infarction (AMI) and diabetes mellitus on health-related quality of life outcomes (QOL). Due to the rising incidence of these comorbid...

    Authors: Ewurabena Simpson and Louise Pilote

    Citation: Health and Quality of Life Outcomes 2005 3:80

    Content type: Research

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  3. The aim of this study was to determine the reliability, validity and responsiveness of the Restless Legs Syndrome Quality of Life questionnaire (RLSQoL) in a clinical trial setting.

    Authors: Linda Abetz, Robert Arbuckle, Richard P Allen, Elena Mavraki and Jeffrey Kirsch

    Citation: Health and Quality of Life Outcomes 2005 3:79

    Content type: Research

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  4. To evaluate the impact of osteoporosis on the patients' quality of life, particularly in the absence of fractures.

    Authors: Maria Luisa Bianchi, Maria Rosa Orsini, Silvia Saraifoger, Sergio Ortolani, Giovanni Radaelli and Simonetta Betti

    Citation: Health and Quality of Life Outcomes 2005 3:78

    Content type: Research

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  5. Patients in emergency departments show a high prevalence of substance use. Quality of life is associated with substance use as well as socioeconomic status. Little is known about quality of life in substance-a...

    Authors: Bruno Neuner, Peter M Miller, Bodo Felsmann, Edith Weiss-Gerlach, Tim Neumann, Klaus Dieter Wernecke and Claudia Spies

    Citation: Health and Quality of Life Outcomes 2005 3:77

    Content type: Research

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  6. The Health of the Nation Outcome Scales was developed to routinely measure outcomes for adults with mental illness. Comparable instruments were also developed for children and adolescents (the Health of the Na...

    Authors: Jane E Pirkis, Philip M Burgess, Pia K Kirk, Sarity Dodson, Tim J Coombs and Michelle K Williamson

    Citation: Health and Quality of Life Outcomes 2005 3:76

    Content type: Review

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  7. While falls and urinary incontinence are prevalent among older patients, who sometimes rely on proxies to provide their health information, the validity of proxy reports of concern about falls and urinary inco...

    Authors: Takahiro Higashi, Ron D Hays, Julie A Brown, Caren J Kamberg, Chau Pham, David B Reuben, Paul G Shekelle, David H Solomon, Roy T Young, Carol P Roth, John T Chang, Catherine H MacLean and Neil S Wenger

    Citation: Health and Quality of Life Outcomes 2005 3:75

    Content type: Research

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  8. Measures of multimorbidity are often applied to source data, populations or outcomes outside the scope of their original developmental work. As the development of a multimorbidity measure is influenced by the ...

    Authors: Martin Fortin, Catherine Hudon, Marie-France Dubois, José Almirall, Lise Lapointe and Hassan Soubhi

    Citation: Health and Quality of Life Outcomes 2005 3:74

    Content type: Research

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  9. Distal radius fractures are common injuries that have an increasing impact on health across the lifespan. The purpose of this study was to identify health impacts in body structure/function, activity, and part...

    Authors: Jocelyn E Harris, Joy C MacDermid and James Roth

    Citation: Health and Quality of Life Outcomes 2005 3:73

    Content type: Research

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  10. A sizable body of research has now examined the complex relationship between quality of life (QoL) and depressive disorder. Uptake of QoL research in relation to bipolar disorder (BD) has been comparatively sl...

    Authors: Erin E Michalak, Lakshmi N Yatham and Raymond W Lam

    Citation: Health and Quality of Life Outcomes 2005 3:72

    Content type: Review

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  11. The European DISABKIDS project aims to enhance the Health Related Quality of Life (HRQoL) of children and adolescents with chronic medical conditions and their families. We describe the development of the seve...

    Authors: Rolanda M Baars, Clare I Atherton, Hendrik M Koopman, Monika Bullinger and Mick Power

    Citation: Health and Quality of Life Outcomes 2005 3:70

    Content type: Research

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  12. The QUALIOST® was designed for use with the SF-36 to measure established osteoporosis-specific quality of life (QoL). The reliability (internal consistency and test-retest) and validity of the questionnaire were ...

    Authors: Christine de la Loge, Kate Sullivan, Robert Pinkney, Patrick Marquis, Christian Roux and Pierre Jean Meunier

    Citation: Health and Quality of Life Outcomes 2005 3:69

    Content type: Research

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  13. The Rhinosinusitis Disability Index (RSDI) is a validated measure of health-related quality of life (HRQL) in rhinitis. Responsiveness of the RSDI to changes in health status over time has not been described.

    Authors: Hubert Chen, Patricia P Katz, Stephen Shiboski and Paul D Blanc

    Citation: Health and Quality of Life Outcomes 2005 3:68

    Content type: Research

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  14. The Eye Allergy Patient Impact Questionnaire (EAPIQ) was developed based on a pilot study conducted in the US and focus groups with eye allergy sufferers in Europe. The purpose of this study was to present the...

    Authors: Michael Alexander, William Berger, Patricia Buchholz, John Walt, Caroline Burk, Jeff Lee, Rob Arbuckle and Linda Abetz

    Citation: Health and Quality of Life Outcomes 2005 3:67

    Content type: Research

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  15. In the last 25 years, assessment of orthopaedic intervention has become patient focused, with the development of self-completion patient-centred outcome measures. The Oxford hip score (OHS) is a joint specific...

    Authors: Vikki Wylde, Ian D Learmonth and Victoria J Cavendish

    Citation: Health and Quality of Life Outcomes 2005 3:66

    Content type: Research

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  16. The importance of evaluating the outcomes of health care from the standpoint of the patient is now widely recognized. The purpose of this study is to develop and test a Japanese version of the National Eye Ins...

    Authors: Yoshimi Suzukamo, Tetsuro Oshika, Mitsuko Yuzawa, Yoshihiro Tokuda, Atsuo Tomidokoro, Kotaro Oki, Carol M Mangione, Joseph Green and Shunichi Fukuhara

    Citation: Health and Quality of Life Outcomes 2005 3:65

    Content type: Research

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  17. In adult quality of life (QOL) research, the QOL construct appears to differ from self-rated health status. Although increased QOL continues to be recognized as an important outcome in health promotion and med...

    Authors: Keith J Zullig, Robert F Valois and J Wanzer Drane

    Citation: Health and Quality of Life Outcomes 2005 3:64

    Content type: Research

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  18. Patients with growth hormone deficiency (GHD) frequently report to suffer from an impaired Quality of Life (QoL) and growth hormone (GH) substitution is found to improve this. However, the same test may be use...

    Authors: Jan Berend Deijen, Lucia I Arwert, Joost Witlox and Madeleine L Drent

    Citation: Health and Quality of Life Outcomes 2005 3:63

    Content type: Research

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  19. Quality of life of stoma patients is increasingly being addressed in clinical trials. However, the instruments used in the majority of these studies have not been validated specifically for stoma patients. The...

    Authors: Luis Prieto, Hanne Thorsen and Kristian Juul

    Citation: Health and Quality of Life Outcomes 2005 3:62

    Content type: Research

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  20. Idiopathic pulmonary fibrosis (IPF) is a debilitating lung disease with a survival of only three to five years from the time of diagnosis. Due to a paucity of studies, large gaps remain in our understanding of...

    Authors: Jeffrey J Swigris, Anita L Stewart, Michael K Gould and Sandra R Wilson

    Citation: Health and Quality of Life Outcomes 2005 3:61

    Content type: Research

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  21. Large variations in pain and function are seen over time in subjects at risk for and with radiographic knee osteoarthritis (OA). We hypothesized that this variation may be related not only to knee OA but also ...

    Authors: Przemyslaw T Paradowski, Martin Englund, L Stefan Lohmander and Ewa M Roos

    Citation: Health and Quality of Life Outcomes 2005 3:59

    Content type: Research

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  22. The age limit for some adult asthma clinical trials has recently been lowered to 12 years. In this study we have made minor modifications to the standardised version of the adult Asthma Quality of Life Questio...

    Authors: Elizabeth F Juniper, Klas Svensson, Ann-Christin Mörk and Elisabeth Ståhl

    Citation: Health and Quality of Life Outcomes 2005 3:58

    Content type: Research

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  23. Most tools for estimating utilities use clinical trial data from general health status models, such as the 36-Item Short-Form Health Survey (SF-36). A disease-specific model may be more appropriate. The object...

    Authors: Leslie A Lenert, Marcia FT Rupnow and Christine Elnitsky

    Citation: Health and Quality of Life Outcomes 2005 3:57

    Content type: Research

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  24. The aim of this study was to evaluate the association between health-related quality of life (HRQL) and disease severity using lung function measures.

    Authors: Elisabeth Ståhl, Anne Lindberg, Sven-Arne Jansson, Eva Rönmark, Klas Svensson, Fredrik Andersson, Claes-Göran Löfdahl and Bo Lundbäck

    Citation: Health and Quality of Life Outcomes 2005 3:56

    Content type: Research

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  25. Quality of life (QoL) is now established as an important outcome for evaluating the impact of disease, and for assessing the efficacy of treatments. However, individuals change with time and the basis on which...

    Authors: Lena Ring, Stefan Höfer, Frank Heuston, David Harris and Ciaran A O'Boyle

    Citation: Health and Quality of Life Outcomes 2005 3:55

    Content type: Research

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  26. We are reporting on the development of a psychosocial screening tool for cancer patients. The tool was to be brief, at a relatively low reading level, capture psychological variables relevant to distress and h...

    Authors: Wolfgang Linden, Dahyun Yi, Maria Cristina Barroetavena, Regina MacKenzie and Richard Doll

    Citation: Health and Quality of Life Outcomes 2005 3:54

    Content type: Research

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  27. Quality of life is a multidimensional construct composed of functional, physical, emotional, social and spiritual well-being. In order to examine how patients with severe diseases view the impact of spirituali...

    Authors: Arndt Büssing, Peter F Matthiessen and Thomas Ostermann

    Citation: Health and Quality of Life Outcomes 2005 3:53

    Content type: Research

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  28. Interventions to improve care for persons with chronic medical conditions often use quality of life (QOL) outcomes. These outcomes may be affected by coexisting (comorbid) chronic conditions as well as the ind...

    Authors: Elizabeth A Bayliss, Jennifer L Ellis and John F Steiner

    Citation: Health and Quality of Life Outcomes 2005 3:51

    Content type: Research

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  29. Sickle cell disease (SCD) is a chronic disease associated with high degrees of morbidity and increased mortality. Health-related quality of life (HRQOL) among adults with sickle cell disease has not been widel...

    Authors: Donna K McClish, Lynne T Penberthy, Viktor E Bovbjerg, John D Roberts, Imoigele P Aisiku, James L Levenson, Susan D Roseff and Wally R Smith

    Citation: Health and Quality of Life Outcomes 2005 3:50

    Content type: Research

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  30. The aim of this study was to assess the possible associations between female androgenetic alopecia (AGA), insulin resistance and health-related quality of life (HRQOL)-linked factors in women. We hypothesized ...

    Authors: Päivi Hirsso, Ulla Rajala, Mauri Laakso, Liisa Hiltunen, Pirjo Härkönen and Sirkka Keinänen-Kiukaanniemi

    Citation: Health and Quality of Life Outcomes 2005 3:49

    Content type: Research

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  31. The five-question Mental Health Inventory (MHI-5) is a brief questionnaire that can be used to screen for depressive symptoms. Removing the 2 anxiety-related items from the MHI-5 yields the MHI-3. We assessed ...

    Authors: Shin Yamazaki, Shunichi Fukuhara and Joseph Green

    Citation: Health and Quality of Life Outcomes 2005 3:48

    Content type: Research

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  32. The International Classification of Functioning, Disability and Health (ICF) was published by the World Health Organization (WHO) to standardize descriptions of health and disability. Little is known about the...

    Authors: Jiro Okochi, Sakiko Utsunomiya and Tai Takahashi

    Citation: Health and Quality of Life Outcomes 2005 3:46

    Content type: Research

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  33. Breast hypertrophy is associated with clinically important morbidity. A prospective study was conducted to assess the change in health-related quality of life (HRQL) following breast reduction mammoplasty. Thi...

    Authors: Achilleas Thoma, Sheila Sprague, Karen Veltri, Eric Duku and William Furlong

    Citation: Health and Quality of Life Outcomes 2005 3:44

    Content type: Research

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  34. To validate a questionnaire to assess the activity impairment associated with uncomplicated urinary tract infection (uUTI).

    Authors: Diane J Wild, Darren J Clayson, Karen Keating and Kathleen Gondek

    Citation: Health and Quality of Life Outcomes 2005 3:42

    Content type: Research

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  35. To determine the psychometric properties of the Hospital Anxiety and Depression Scale (HADS) in patients with breast cancer and determine the suitability of the instrument for use with this clinical group.

    Authors: Jacqui Rodgers, Colin R Martin, Rachel C Morse, Kate Kendell and Mark Verrill

    Citation: Health and Quality of Life Outcomes 2005 3:41

    Content type: Research

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  36. Quality of life (QoL) of patients has become a central evaluation parameter that also acts as an aid for decisions related to treatment strategies particularly for patients with chronic illnesses. In Germany, ...

    Authors: Thomas Ostermann, Arndt Büssing, Andre-Michael Beer and Peter F Matthiessen

    Citation: Health and Quality of Life Outcomes 2005 3:40

    Content type: Research

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  37. Although patients with chronic hepatitis C (CHC) have been found to have reduced quality of life, little is known about how other characteristics affect their quality of life. The purpose of this study was to ...

    Authors: Sara H Olson, Sandy Iyer, Jennifer Scott, Orry Erez, Shelby Samuel, Temima Markovits, Myron Schwartz, Charlene Toro, Maya Gambarin-Gelwan and Robert C Kurtz

    Citation: Health and Quality of Life Outcomes 2005 3:39

    Content type: Research

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  38. In methodological studies and outcomes research, questionnaires often comprise several health-related quality of life (HRQoL) measures. Previous psychological studies have suggested that changing the sequentia...

    Authors: Yin-Bun Cheung, Celestine Lim, Cynthia Goh, Julian Thumboo and Joseph Wee

    Citation: Health and Quality of Life Outcomes 2005 3:37

    Content type: Research

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  39. The Dermatology Quality Life Index (DLQI) has seen widespread use as a health-related quality of life measure for a variety of dermatological diseases. The purpose of this study was to estimate the minimal imp...

    Authors: Richard Shikiar, Gale Harding, Michael Leahy and Richard D Lennox

    Citation: Health and Quality of Life Outcomes 2005 3:36

    Content type: Research

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  40. Chronic liver disease especially liver cirrhosis is one of the medical problems that substantially reduces the quality of life of its victims. Because of the chronic and irreversible nature of the disease, it ...

    Authors: Mitra Zandi, Mohsen Adib-Hajbagheri, Robabeh Memarian, Anooshiravan Kazem Nejhad and Seyed Moayed Alavian

    Citation: Health and Quality of Life Outcomes 2005 3:35

    Content type: Research

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  41. Health-related quality of life (HRQOL) measurement has emerged as an important health outcome in clinical trials, clinical practice improvement strategies, and healthcare services research and evaluation. HRQO...

    Authors: James W Varni, Tasha M Burwinkle and Mariella M Lane

    Citation: Health and Quality of Life Outcomes 2005 3:34

    Content type: Review

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  42. Whether responsiveness represents a measurement property of health-related quality of life (HRQL) instruments that is distinct from reliability and validity is an issue of debate. We addressed the claims of a ...

    Authors: Milo A Puhan, Dianne Bryant, Gordon H Guyatt, Diane Heels-Ansdell and Holger J Schünemann

    Citation: Health and Quality of Life Outcomes 2005 3:33

    Content type: Research

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  43. Living with a chronic disease, such as primary antibody deficiency, will often have consequences for quality of life. Previous quality-of-life studies in primary antibody deficiency patients have been limited ...

    Authors: Hanne Marie Høybråten Sigstad, Asbjørg Stray-Pedersen and Stig S Frøland

    Citation: Health and Quality of Life Outcomes 2005 3:31

    Content type: Research

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