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  1. Myocardial infarction and unstable angina are prevalent in Korea. The MacNew Heart Disease health-related quality of life questionnaire is a widely used patient-reported outcome measure for patients with heart...

    Authors: Sun Hyoung Bae, Myeong-Ho Yoon and Jin-Hee Park

    Citation: Health and Quality of Life Outcomes 2021 19:196

    Content type: Research

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  2. Although several studies have reported an association between tuberculosis and health-related quality of life, the change in health-related quality of life after pulmonary tuberculosis has been rarely studied....

    Authors: Sang Hyuk Kim, Hyun Lee and Youlim Kim

    Citation: Health and Quality of Life Outcomes 2021 19:195

    Content type: Research

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  3. A person’s chronic health condition or disability can have a huge impact on the quality of life (QoL) of the whole family, but this important impact is often ignored. This literature review aims to understand ...

    Authors: R. Shah, F. M. Ali, A. Y. Finlay and M. S. Salek

    Citation: Health and Quality of Life Outcomes 2021 19:194

    Content type: Review

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    The Correction to this article has been published in Health and Quality of Life Outcomes 2021 19:211

  4. This study was conducted in a general population of schoolchildren in Sweden, with the aim to assess the psychometric properties of a generic preference-based health related quality of life (HRQoL) instrument,...

    Authors: Kristina Lindvall, Masoud Vaezghasemi, Inna Feldman, Anneli Ivarsson, Katherine J. Stevens and Solveig Petersen

    Citation: Health and Quality of Life Outcomes 2021 19:193

    Content type: Research

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  5. The aim of this cross-sectional study was to evaluate the effect of family functioning on oral health related quality of life (OHRQoL) and dental caries status among 4- to 6-year-old Chinese pre-school childre...

    Authors: Sobia Bilal, Anshad Mohamed Abdulla, Niekla Survia Andiesta, Muneer Gohar Babar and Allan Pau

    Citation: Health and Quality of Life Outcomes 2021 19:192

    Content type: Research

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  6. The Musculoskeletal Health Questionnaire (MSK-HQ) is a recently developed generic questionnaire that consists of 14 items assessing health status in people with musculoskeletal disorders. The objective was to ...

    Authors: Alexander Tingulstad, Maurits W. Van Tulder, Tarjei Rysstad, Anne Therese Tveter, Jonathan C. Hill and Margreth Grotle

    Citation: Health and Quality of Life Outcomes 2021 19:191

    Content type: Research

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  7. The short form of the Stroke Impact Scale (SF-SIS) consists of eight questions and provides an overall index of health-related quality of life after stroke. The goal of the study was the evaluation of construc...

    Authors: Anna Coppers, Jens Carsten Möller and Detlef Marks

    Citation: Health and Quality of Life Outcomes 2021 19:190

    Content type: Research

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  8. The Diabetes Health Profile (DHP‐18), structured in three dimensions (psychological distress (PD), barriers to activity (BA) and disinhibited eating (DE)), assesses the psychological and behavioural burden of ...

    Authors: Ikram Benazizi, Mari Carmen Bernal-Soriano, Yolanda Pardo, Aida Ribera, Andrés Peralta-Chiriboga, Montserrat Ferrer, Alfonso Alonso-Jaquete, Jordi Alonso, Blanca Lumbreras and Lucy Anne Parker

    Citation: Health and Quality of Life Outcomes 2021 19:189

    Content type: Research

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  9. As a result of high transmission and mortality rates, the Covid-19 pandemic has led to a worldwide health crisis, isolation, and widespread fear, therefore negatively influencing people’s quality of life (QOL)...

    Authors: Ali Hasanpour Dehkordi, Marzieh Aslani, Abbas Ebadi, Selman Repišti, Borhan Moradveisi and Reza Ghanei Gheshlagh

    Citation: Health and Quality of Life Outcomes 2021 19:188

    Content type: Research

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  10. Advances in paediatric cardiology have improved the prognosis of children with inherited cardiac disorders. However, health-related quality of life (QoL) and physical activity have been scarcely analysed in ch...

    Authors: Pascal Amedro, Oscar Werner, Hamouda Abassi, Aymeric Boisson, Luc Souilla, Sophie Guillaumont, Johanna Calderon, Anne Requirand, Marie Vincenti, Victor Pommier, Stefan Matecki, Gregoire De La Villeon, Kathleen Lavastre, Alain Lacampagne, Marie-Christine Picot, Constance Beyler…

    Citation: Health and Quality of Life Outcomes 2021 19:187

    Content type: Study protocol

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  11. Kangaroo mother care is known to help save the lives of preterm and low birthweight infants, particularly in resource-limited health settings, yet barriers to implementation have been documented. Mothers and t...

    Authors: Alinane Linda Nyondo-Mipando, Mai-Lei Woo Kinshella, Tamanda Hiwa, Sangwani Salimu, Mwai Banda, Marianne Vidler, Elizabeth Molyneux, Queen Dube, David M. Goldfarb and Kondwani Kawaza

    Citation: Health and Quality of Life Outcomes 2021 19:186

    Content type: Research

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  12. The objective of this study was to verify the reliability, discriminatory power and construct validity of the Kidscreen-27 questionnaire in Brazilian adolescents.

    Authors: Pablo Magno da Silveira, Alexsandra da Silva Bandeira, Marcus Vinicius Veber Lopes, Adriano Ferreti Borgatto and Kelly Samara da Silva

    Citation: Health and Quality of Life Outcomes 2021 19:185

    Content type: Research

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  13. In clinical trials for rare diseases, such as Duchenne muscular dystrophy, clinical outcome assessments (COA) used to assess treatment benefit are often generic and may not be sensitive enough to detect change...

    Authors: Hannah Staunton, Claire Trennery, Rob Arbuckle, Maitea Guridi, Elena Zhuravleva, Pat Furlong, Ryan Fischer and Rebecca Hall

    Citation: Health and Quality of Life Outcomes 2021 19:184

    Content type: Research

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  14. High prevalence rates in diabetes-related distress have been observed in several studies; however, in the region of Sub-Saharan Africa evidence is lacking as is, for example, the case for Rwanda, where diabete...

    Authors: Charilaos Lygidakis, Jean Paul Uwizihiwe, Michela Bia, Per Kallestrup, Damas Dukundane, Brenda Asiimwe-Kateera, Simon Pierre Niyonsenga and Claus Vögele

    Citation: Health and Quality of Life Outcomes 2021 19:183

    Content type: Research

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  15. Pregnant women experience physical, physiological, and mental changes. Health-related quality of life (HRQoL) is a relevant indicator of psychological and physical behaviours, changing over the course of pregn...

    Authors: Huailiang Wu, Weiwei Sun, Hanqing Chen, Yanxin Wu, Wenjing Ding, Shangqiang Liang, Xinyu Huang, Haitian Chen, Qing Zeng, Zhuyu Li, Peng Xiong, Jian Huang, Babatunde Akinwunmi, Casper J. P. Zhang and Wai-Kit Ming

    Citation: Health and Quality of Life Outcomes 2021 19:182

    Content type: Research

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  16. The study aimed to appraise the health-related quality of life (HRQoL) measured by the five-level EuroQol-5 dimensions (EQ-5D-5L) in amyotrophic lateral sclerosis (ALS), and to explore the associations between...

    Authors: Qian-Qian Wei, Yanbing Hou, Yongping Chen, Ruwei Ou, Bei Cao, Lingyu Zhang, Tianmi Yang and Huifang Shang

    Citation: Health and Quality of Life Outcomes 2021 19:181

    Content type: Research

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  17. The Suboptimal Health Status Questionnaire-25 (SHS-Q-25) developed to measure Suboptimal Health Status has been used worldwide, but its construct validity has only been tested in the Chinese population. Applyi...

    Authors: Eric Adua, Ebenezer Afrifa-Yamoah, Kwasi Frimpong, Esther Adama, Shantha P. Karthigesu, Enoch Odame Anto, Emmanuel Aboagye, Yuxiang Yan, Youxin Wang, Xuerui Tan and Wei Wang

    Citation: Health and Quality of Life Outcomes 2021 19:180

    Content type: Research

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  18. Fatigability has recently emerged in oncology as a concept that anchors patients’ perceptions of fatigue to defined activities of specified duration and intensity. This study aimed to examine the psychometric ...

    Authors: Min Kyeong Jang, Sue Kim, Chang Gi Park, Eileen G. Collins, Lauretta T. Quinn, Nancy W. Glynn and Carol Estwing Ferrans

    Citation: Health and Quality of Life Outcomes 2021 19:179

    Content type: Research

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  19. Women with breast cancer are prone to have mental stress and be stimulated by the fear of progression (FOP), then giving rise to a lower quality of life (QOL). The study aimed to examine the relationships betw...

    Authors: Yue Ban, Mengyao Li, Mingli Yu and Hui Wu

    Citation: Health and Quality of Life Outcomes 2021 19:178

    Content type: Research

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  20. Caregivers are major contributor to the self-care of patients with heart failure. The Caregiver Contribution to Self-Care of Heart Failure Index (CC-SCHFI) measures these contributions across three scales: sel...

    Authors: Nittaya Srisuk, Nutchanath Wichit, David R. Thompson and Chantal F. Ski

    Citation: Health and Quality of Life Outcomes 2021 19:177

    Content type: Research

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  21. Sleep disruption is a prevalent symptom reported by survivors of childhood cancer. However, there is no validated instrument for assessing this symptom in this population group. To bridge the literature gap, t...

    Authors: K. Y. Ho, Katherine K. W. Lam, W. Xia, J. O. K. Chung, Ankie T. Cheung, Laurie L. K. Ho, S. Y. Chiu, Godfrey C. F. Chan and William H. C. Li

    Citation: Health and Quality of Life Outcomes 2021 19:176

    Content type: Research

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  22. Although telemedical applications are increasingly used in the area of both mental and physical illness, there is no quality of life (QoL) instrument that takes into account the specific context of the healthc...

    Authors: Klara Greffin, Silke Schmidt, Neeltje van den Berg, Wolfgang Hoffmann, Oliver Ritter, Michael Oeff, Georg Schomerus and Holger Muehlan

    Citation: Health and Quality of Life Outcomes 2021 19:175

    Content type: Research

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  23. The main aim of post-mastectomy breast reconstruction is to improve the patient’s quality of life, which makes high-quality and validated patient-reported outcome measurements essential. None of the establishe...

    Authors: Lynne Kamya, Emma Hansson, Linn Weick and Emma Hansson

    Citation: Health and Quality of Life Outcomes 2021 19:174

    Content type: Research

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  24. The development of the minimum clinical important difference (MCID) can make it easier for researchers or doctors to judge the significance of research results and the effect of intervention measures, and impr...

    Authors: Dandan Ren, Ting Wu, Chonghua Wan, Gaofeng Li, Yanbo Qi, Yujing Fang and Jiudi Zhong

    Citation: Health and Quality of Life Outcomes 2021 19:173

    Content type: Research

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  25. Neurodegenerative diseases (NDs) are one of the main causes of disability and dependence that have a great impact both on the quality of life of people with disabilities and their families. A majority of peopl...

    Authors: Marta Badia, M. Begoña Orgaz, Isabel Vicario-Molina, Eva González-Ortega, María Gómez-Vela, Alba Aza and M. Antonia Martín-Delgado

    Citation: Health and Quality of Life Outcomes 2021 19:172

    Content type: Research

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  26. Idiopathic central precocious puberty (ICPP) reduces patient health-related quality of life (HRQoL). The impacts of disease and treatment on families are also an important concern. This study aimed to assess t...

    Authors: Hong Yang, Shunqing Luo, Xiaohua Liang, Qin Lin, Ting Cheng, Li Zeng, Fang Tang and Di Wu

    Citation: Health and Quality of Life Outcomes 2021 19:171

    Content type: Research

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  27. Day care service (DCS) provides various activities in a professional environment to meet the old people with functional limitations. However, relatively little is known about the effects of DCS on physical and...

    Authors: Cheng-Fu Lin, Jia-Jyun Wu, Yu-Hui Huang, Li-Ying Ju, Shih-Yi Lin, Ying-Chyi Chou and Chu-Sheng Lin

    Citation: Health and Quality of Life Outcomes 2021 19:170

    Content type: Research

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  28. Exercise adherence is important for achieving a long-term effect from musculoskeletal management. The Exercise Adherence Rating Scale (EARS), which was developed in 2017 as a patient reported outcome measure t...

    Authors: Hiroshi Takasaki, Shota Kawazoe, Takahiro Miki, Hiroki Chiba and Emma Godfrey

    Citation: Health and Quality of Life Outcomes 2021 19:169

    Content type: Research

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  29. According to the World Health Organization (WHO), hearing loss (HL) affects up to 15% of the world’s adult population. Coping and personality are hypothesized to underlie quality of life (QoL) and distress sco...

    Authors: Øyvind Nordvik, Peder O. Laugen Heggdal, K. Jonas Brännström, Anne Kari Aarstad and Hans Jørgen Aarstad

    Citation: Health and Quality of Life Outcomes 2021 19:168

    Content type: Research

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  30. Social deprivation has been shown to affect access to health care services, and influences outcomes for a variety of physical and psychological conditions. However, the impact on patient satisfaction remains l...

    Authors: Andrew R. Stephens, Jared W. Potter, Andrew R. Tyser and Nikolas H. Kazmers

    Citation: Health and Quality of Life Outcomes 2021 19:167

    Content type: Research

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  31. The aim of this study was to provide a path model for assessing the direct and/or indirect effects of psychological/behavioral parameters on health-related quality of life among women with vaginismus.

    Authors: Atefeh Velayati, Shahideh Jahanian Sadatmahalleh, Saeideh Ziaei and Anoshirvan Kazemnejad

    Citation: Health and Quality of Life Outcomes 2021 19:166

    Content type: Research

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  32. Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact are the four oral health-related quality of life (OHRQoL) dimensions (4D) or areas in which oral disorders impact pediatric patients...

    Authors: Katrin Bekes, Mike T. John, Ksenija Rener-Sitar, Mohammad H. Al-Harthy, Ambra Michelotti, Daniel R. Reissmann, Julijana Nikolovska, Sahityaveera Sanivarapu, Folake B. Lawal, Thomas List, Sanja Peršić Kiršić, Ljiljana Strajnić, Rodrigo Casassus, Kazuyoshi Baba, Martin Schimmel, Ama Amuasi…

    Citation: Health and Quality of Life Outcomes 2021 19:165

    Content type: Research

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  33. There has been limited success in achieving integration of patient-reported outcomes (PROs) in clinical trials. We describe how stakeholders envision a solution to this challenge.

    Authors: Theresa M. Coles, Adrian F. Hernandez, Bryce B. Reeve, Karon Cook, Michael C. Edwards, Marc Boutin, Elizabeth Bush, Arnold Degboe, Lothar Roessig, Amy Rudolph, Pauline McNulty, Nikunj Patel, Trish Kay-Mugford, Margaret Vernon, Michael Woloschak, Gustavo Buchele…

    Citation: Health and Quality of Life Outcomes 2021 19:164

    Content type: Commentary

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  34. An automated web-based assessment and monitoring system (www.​psynary.​com) has been developed to assist non-specialist clinicians in managing common mood and ...

    Authors: Yuki Takao, Eduardo Figueroa, Kevin Fernand Jean Berna, Youjin Jo, Lee Andrew Kissane, Kimio Yoshimura, Richard Tranter and Richard J Porter

    Citation: Health and Quality of Life Outcomes 2021 19:163

    Content type: Research

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  35. The EQ-5D-3L is a widely used generic health-related quality of life measure commonly applied to describe health outcomes and to measure disease burden. The aim of this study was to generate Brazilian populati...

    Authors: Marisa Santos, Andrea L. Monteiro and Bráulio Santos

    Citation: Health and Quality of Life Outcomes 2021 19:162

    Content type: Research

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  36. This letter was written to address two concerns about the results of the paper published by Zeynep et al. (BMC Health Qual Life Outcomes 18:265, 2020). First, the differences between the two groups in the envi...

    Authors: Kazuoki Inoue, Jun Watanabe and Eiichi Kakehi

    Citation: Health and Quality of Life Outcomes 2021 19:161

    Content type: Letter to the Editor

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    The Letter to this article has been published in Health and Quality of Life Outcomes 2021 19:203

  37. An increased prevalence of adolescent metabolic syndrome (MS) is associated with adulthood cardiovascular diseases. This study aimed to explore the potential relationship of quality of life (QoL) and personali...

    Authors: Xiaohua Liang, Peng Zhang, Shunqing Luo, Guifang Zhang, Xian Tang and Lingjuan Liu

    Citation: Health and Quality of Life Outcomes 2021 19:160

    Content type: Research

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  38. The National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) was developed to accurately assess the pain, urinary symptoms, and quality of life related to chronic prostatitis/chronic pelvic p...

    Authors: Rong-liang Dun, Jennifer Tsai, Xiao-hua Hu, Jian-min Mao, Wen-jing Zhu, Guang-chong Qi and Yu Peng

    Citation: Health and Quality of Life Outcomes 2021 19:159

    Content type: Review

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  39. Patient reported outcome measures (PROMs) are used to understand the impact of lower limb reconstruction surgery on patients’ quality of life (QOL). Existing measures have not been developed to specifically ca...

    Authors: H. Leggett, A. Scantlebury, A. Byrne, M. Harden, C. Hewitt, G. O’Carroll, H. Sharma and C. McDaid

    Citation: Health and Quality of Life Outcomes 2021 19:158

    Content type: Review

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  40. The 12-item Short-Form Health Survey version 2 (SF-12v2), a widely used, generic patient-reported measure of health status that provides summary scores of physical and mental health. No study to date has exami...

    Authors: Sze-Ee Soh, Renata Morello, Darshini Ayton, Susannah Ahern, Ri Scarborough, Claire Zammit, Margaret Brand, Robert G. Stirling and John Zalcberg

    Citation: Health and Quality of Life Outcomes 2021 19:157

    Content type: Research

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  41. As China’s aging trend intensifies and the proportion of empty nests increases, the health-related quality of life of the elderly is the focus of social attention. Previous studies focused on the quality of li...

    Authors: Chichen Zhang, Yuan Cai, Yaqing Xue, Xiao Zheng, Xiaozhao Yang, Jiao Lu, Lihong Hou and Mimi Li

    Citation: Health and Quality of Life Outcomes 2021 19:156

    Content type: Research

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  42. The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respect...

    Authors: A. M. Garratt, H. Furunes, C. Hellum, T. Solberg, J. I. Brox, K. Storheim and L. G. Johnsen

    Citation: Health and Quality of Life Outcomes 2021 19:155

    Content type: Research

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  43. We conducted a real-life study of health-related quality of life (HRQoL) transformation before and 12 weeks after sofosbuvir and daclatasvir therapy in HCV/HIV co-infected patients. Factors related to the sign...

    Authors: Evy Yunihastuti, Fhadilla Amelia, Arini Ika Hapsari, Bramantya Wicaksana, Veritea Natali, Alvina Widhani, Andri Sanityoso Sulaiman and Teguh Harjono Karjadi

    Citation: Health and Quality of Life Outcomes 2021 19:154

    Content type: Research

    Published on:

  44. The Wisconsin Upper Respiratory Symptom Survey for Kids (WURSS-K) is a self-administered questionnaire developed to evaluate the severity of the common cold. It is a patient-oriented instrument that evaluates ...

    Authors: Katarzyna Ostrzyżek-Przeździecka, Mariusz Panczyk, Aleksandra Ratajczak, Michał Bronikowski and Wojciech Feleszko

    Citation: Health and Quality of Life Outcomes 2021 19:153

    Content type: Research

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  45. With the increase of the number of smokers, tobacco exposure among pregnant women is becoming more and more common. Pregnant women exposed to first-hand smoke and second-hand smoke are susceptible to physiolog...

    Authors: Weiwei Sun, Xinyu Huang, Huailiang Wu, Casper J. P. Zhang, Zongzhi Yin, Qianqian Fan, Huiyun Wang, Pallavi Jayavanth, Babatunde Akinwunmi, Yanxin Wu, Zilian Wang and Wai-kit Ming

    Citation: Health and Quality of Life Outcomes 2021 19:152

    Content type: Research

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  46. This study aims to explore the incidence of hypoglycemia in patients with type 2 diabetes mellitus (T2DM) and the influence of hypoglycemia on the specific quality of life in T2DM patients.

    Authors: Chao Wu, Yi-Ling Ge, Xin-Yan Zhang, Ming-Chao Liu, Chun-Ni Heng, Lin-Yuan Zhang, Yan-Ling Du, Shi-Zhe He, Lei Shang and Hong-Juan Lang

    Citation: Health and Quality of Life Outcomes 2021 19:151

    Content type: Research

    Published on:

  47. Degenerative cervical myelopathy (DCM) can significantly impair a patient’s quality of life (QOL). In this study, we aimed to identify predictors associated with QOL improvement after surgery for DCM.

    Authors: Hiroyuki Inose, Takashi Hirai, Toshitaka Yoshii, Atsushi Kimura, Katsushi Takeshita, Hirokazu Inoue, Asato Maekawa, Kenji Endo, Takuya Miyamoto, Takeo Furuya, Akira Nakamura, Kanji Mori, Shunsuke Kanbara, Shiro Imagama, Shoji Seki, Shunji Matsunaga…

    Citation: Health and Quality of Life Outcomes 2021 19:150

    Content type: Research

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  48. The diagnosis of breast cancer and the subsequent treatment undermine patients’ participation in social activities. This study aimed to carry out a cross-cultural adaption and analysis of the construct validit...

    Authors: Tingting Cai, Qingmei Huang, Fulei Wu and Changrong Yuan

    Citation: Health and Quality of Life Outcomes 2021 19:149

    Content type: Research

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  49. The assessment of patient satisfaction during treatment is essential to provide patient-centered high-quality cancer care. Nevertheless, no German instrument assesses patient satisfaction with comprehensive ca...

    Authors: Peter Esser, Leon Sautier, Susanne Sarkar, Georgia Schilling, Carsten Bokemeyer, Uwe Koch, Michael Friedrich, Gautier Defossez and Anja Mehnert-Theuerkauf

    Citation: Health and Quality of Life Outcomes 2021 19:147

    Content type: Research

    Published on:

  50. The goal of this article was to research the psychometric properties of the WHOQOL-BREF(PT) instrument in a sample of elderly citizens residing in a rural area in their own homes or at family members’ or frien...

    Authors: Margarida Goes, Manuel Lopes, João Marôco, Henrique Oliveira and César Fonseca

    Citation: Health and Quality of Life Outcomes 2021 19:146

    Content type: Research

    Published on:

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