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Table 3 Stepwise multivariate regression model of the adjusted associations between demographic and clinical variables, and physical and mental components of Health-related quality of life in people living with HIV (n = 245)

From: Factors associated with health-related quality of life in people living with HIV in Norway

 

SF-36-PCS

SF-36-MCS

 

Full model

B (95% CI)

p-value

Final model

B (95% CI)

p-value

Full model

B (95% CI)

p-value

Final model

B (95% CI)

p-value

Demographic variables

Age (y)

–0.11 (–0.23, –0.00)

.045*

–0.12 (–0.21, –0.02)

.020*

0.14 (0.02, 0.25)

.020*

0.12 (0.02, 0.23)

.018*

Woman

2.16 (–0.35, 4.66)

.091

1.76 (–0.58, 4.11)

.140

–2.82 (–5.38, –0.26)

.031*

–2.08 (–4.42, 0.27)

.083

Living together

0.45 (–1.84, 2.74)

.669

  

–0.25 (–2.59, 2.10)

.837

  

Native continent

Norway

0.88 (–2.25, 4.00)

.581

  

–1.82 (–5.02, 1.38)

.264

  

Rest of Europe

1.44 (–3.34, 6.23)

.553

  

–5.86 (–10.76, –0.96)

.019*

–5.14 (–9.75, –0.54)

.029*

America

3.95 (–1.73, 9.63)

.172

  

–2.44 (–8.25, 3.37)

.409

  

Asia

Africa (ref)

–2.33 (–5.62, 0.96)

.164

–2.57 (–5.59, 0.45)

.094

0.99 (–2.37, 4.36)

.561

  

Unemployed/undergoing rehabilitation/disabled

–3.40 (–5.95, –0.84)

.009*

–6.79 (–6.00, –0.98)

.007*

1.45 (–1.16, 4.07)

.275

  

Clinical variables

Comorbidity

–2.50 (–4.13, –0.87)

.003*

–2.46 (–4.04, –0.88)

.015*

0.19 (–1.48, 1.86)

.824

  

HIV viral load < 50 copies m/L

0.88 (–2.26, 4.01)

.583

  

–1.48 (–4.69, 1.73)

.365

  

Time since diagnosis (y)

–0.02 (–0.18, 0.14)

.826

  

–0.15 (–0.31, 0.02)

.080

–0.16 (–0.32, –0.00)

.046*

HSCL-25

–3.31 (–5.97, –0.65)

.015*

–3.18 (–5.73, –0.62)

.015*

–15.31 (–18.04, –12.59)

 < .001*

–15.01 (–17.49, –12.53)

 < .001*

Drug abuse, at risk

3.12 (–1.32, 5.37)

.233

3.14 (0.20, 6.09)

.037*

–2.39 (–5.50, 0.72)

.131

–2.43 (–5.44, 0.59)

.114

Alcohol abuse, at risk

2.03 (–1.32, 5.37)

.233

2.28 (–0.93, 5.49)

.162

–3.60 (–7.03, –0.18)

.039*

–4.14 (–7.41, –0.88)

.013*

Fatigued

–6.75 (–9.66, –3.84)

 < .001*

–6.79 (–9.62, –3.96)

 < .001*

–5.47 (–8.46, –2.49)

 < .001*

–5.49 (–8.36, –2.61)

 < .001*

R2

34.2%

 

35.2%

 

61.9%

 

62.4%

 
  1. The final model used a backward-step procedure to define the included variables. The full model included all of the selected variables entered into the model, and the final model included variables in the final step using the backward procedure
  2. CI confidence interval, SF-36 36-item Short Form Health Survey questionnaire (range 0–100) where 100 indicates a high Health-related quality of life, SF-36-PCS physical component summary (range 0–100), SF-36-MCS mental component summary (range 0–100), Comorbidity: comorbidity including Hepatitis C (range 0–10), Hopkins Symptoms Checklist-25 (range 1–4), Drug abuse, at risk: Drug Use Disorder Identification Test > 1(f) or > 6 (m) (range 0–44), Alcohol abuse, at risk: Alcohol Use Disorder Identification Test > 6 (f) or > 8 (m) (range 0–40), Fatigued: Chalder Fatigue Scale > 4 (range 0–11)
  3. *Significant at 5% level
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Health and Quality of Life Outcomes

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