Factors affecting the quality of life after ischemic stroke in young adults: a scoping review

Gurková, Elena; Štureková, Lenka; Mandysová, Petra; Šaňák, Daniel

doi:10.1186/s12955-023-02090-5

Health and Quality of Life Outcomes

Table 3 Predictors of HRQoL in young adults with IS

From: Factors affecting the quality of life after ischemic stroke in young adults: a scoping review

Category	Factors	Measure	Statistical analyses	Main findings
Clinically related factors	Neurological outcomes, the severity of stroke	NIHSS	(SEM)	The severity of the stroke at the time of follow-up had significant direct, indirect and total effects on HRQoL [20]
	Functional outcomes, independence in ADL	mRS, BI	Regression model	Favourable initial functional status and higher independence in ADL: higher HRQOL [56]
	Functional outcomes, independence in ADL	mRS, BI	SEM	The functional status and higher independence in ADL at the time of follow-up had significant direct, and total effects on HRQoL [20]
	Motor impairment	MRC	Regression model	Lower motor dysfunction: higher HRQOL [56]
	Motor impairment	SIS	Regression model	Lower motor dysfunction: higher HRQOL [56]
	Hand function	Upper extremity function of the SIS	Regression model	HRQoL at 12 months after stroke was predicted by hand function explaining a total of 32% of variance [56]
	Fatigue	FSS, FAS	Regression model	Higher levels of fatigue: lower HRQOL [57]
	Coronary heart disease during the index event		Regression model	No coronary heart disease during the index event: higher HRQOL [59]
Psychosocial factors	Depression	BDI, HADS, MADRS	Regression model	Higher levels of depression: lower HRQOL [57, 59]
	Depression	BDI, HADS, MADRS	SEM	Depression at the time of follow-up had significant indirect, and total effects on HRQoL [20]
	Anxiety	HADS	Regression model	Higher levels of anxiety: lower HRQOL [57]
	Fear of stroke recurrence	FSRS	SEM	Fear of stroke recurrence at the time of follow-up had significant direct, indirect, and total effects on HRQoL [20]
	Restrictions and limitations in leisure activities	MYS questionnaire	Regression model	Higher levels of restrictions and limitations in leisure activities: lower HRQOL [58]
	Self-perceived health status	HPQ	SEM	General health perception had a significant direct effect on the HRQoL [20]
	Sense of coherence	SCS	Regression model	The higher initial sense of coherence: higher HRQOL [56]
	Return to work/unemployment		Regression model	Return to work: higher HRQoL
	Return to work/unemployment		Regression model	Unemployment: lower HRQoL [20, 57,58,59]
	Social support	ENRICHD SSI	SEM	Higher social support: higher HRQOL
	Social support	ENRICHD SSI	SEM	Social support had significant direct, and total effects on HRQoL [20]

BI Barthel Index, BDI Beck Depression Inventory, ENRICHD SSI Coronary Heart Disease Patients Social Support Inventory, FAS Fatigue Assessment Scale, FSS Fatigue Severity Scale,– FSRS Fear of Stroke Recurrence Scale, HPQ Health Perception Questionnaire, HADS Hospital Anxiety and Depression Scale, ADL Activities of Daily Living, MRC Medical Research Council motor scale, MMSE Mini-Mental State Examination, MMMS Modified Mini-Mental State Examination, mRS Modified Rankin Scale, MADRS Montgomery-Åsberg Depression Rating Scale, NIHSS National Institutes of Health Stroke Scale, SCS Sense of Coherence scale, SIS Stroke Impact scale, SEM Structural equation modelling

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ISSN: 1477-7525

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