Development and content validation of patient-reported outcomes tools for ulcerative colitis and Crohn’s disease in adults with moderate-to-severe disease

Table 2 Symptoms reported by at least four participants in the UC study (N = 12)^a

Symptom^b	Total reported^c	Spontaneous report^d	Probed report^d
Urgent bowel movements^e	12 (100)	6 (50)	6 (50)
Abdominal pain^e	11 (92)	10 (91)	1 (9)
Frequent bowel movements^e	11 (92)	9 (82)	2 (18)
Bloody stools^e	10 (83)	8 (80)	2 (20)
Diarrhea/watery stools^e	10 (83)	9 (90)	1 (10)
Nausea	6 (50)	2 (33)	4 (67)
Fatigue	5 (42)	4 (80)	1 (20)
Lack of appetite	4 (33)	4 (100)	0 (0)

PRO, patient-reported outcomes; UC, ulcerative colitis
^aSymptoms reported spontaneously by 1–3 participants: bloating (n = 3), joint pain (n = 2), vomiting (n = 2), constipation (n = 1), dehydration (n = 1), difficulty swallowing (n = 1), dizziness (n = 1), fever (n = 1), excessive gas (n = 1), general discomfort (n = 1), lower back pain (n = 1), malaise (n = 1), mouth sores (n = 1), mucus in stools (n = 1), skin discoloration (n = 1), and abdominal spasms (n = 1)
^bParticipants reported on current and past symptoms experienced
^cData are number of participants (%); percentage calculated as a proportion of the overall group (N = 12)
^dData are number of participants (%); percentage calculated as a proportion of the ‘total reported’
^eItems in the PRO-UC Diary

ISSN: 1477-7525