Health-related quality of life among Chinese patients with Crohn’s disease: a cross-sectional survey using the EQ-5D-5L

Table 3 Ordinal least squares (OLS), Tobit regression and Logistic regression for EQ-5D-5L utility

Variables	Univariate			OLS			Tobit			Logistic regression
Variables	β	SE	P	β	SE	P	β	SE	P	OR	SE	P
Gender
Female	− 0.067	0.018	0.000	− 0.027	0.015	0.258	− 0.029	0.016	0.219	1.109	0.536	0.923
Age group
30–49	0.008	0.017	0.620
≧ 50	− 0.040	0.046	0.379
CD location
L2	− 0.110	0.024	0.000
L3	− 0.045	0.017	0.008
L4	0.118	0.112	0.293
CDAI
150–450	− 0.135	0.014	0.000	− 0.089	0.015	0.000	− 0.104	0.016	0.000	0.036	0.756	0.000
Duration of CD	0.003	0.002	0.298
BMI	0.012	0.002	0.000	0.002	0.002	0.662	0.003	0.002	0.533	1.165	0.080	0.136
ESR	− 0.002	0.000	0.000	0.000	0.000	0.810	0.000	0.001	0.837	0.957	0.021	0.119
CRP	− 0.002	0.000	0.000	0.000	0.000	0.662	0.000	0.000	0.718	1.020	0.014	0.287
Medications
5-Aminosalicylates	− 0.036	0.020	0.070	− 0.009	0.016	0.766	− 0.006	0.017	0.869	1.055	0.574	0.925
Corticosteroids	− 0.044	0.021	0.040	− 0.016	0.018	0.662	− 0.015	0.019	0.658	0.787	0.616	0.852
Immunomodulators	− 0.020	0.020	0.323
Biologics	0.089	0.017	0.000	0.011	0.018	0.766	0.020	0.020	0.633	2.906	0.759	0.287
Antibiotics	− 0.113	0.015	0.000	− 0.053	0.017	0.011	− 0.056	0.018	0.011	0.198	0.581	0.032
Expenditure
8000–16,000	− 0.045	0.021	0.031	0.004	0.018	0.848	− 0.001	0.020	0.977	1.662	0.723	0.056
16,000–24,000	− 0.078	0.021	0.000	− 0.009	0.020	0.782	− 0.009	0.022	0.908	0.598	0.714	0.707
> 24,000	− 0.149	0.021	0.000	− 0.055	0.022	0.055	− 0.058	0.023	0.056	0.753	0.765	0.852
AIC				− 357.32			− 254.65			147.37

Reference level: male, age < 30 years old, L1, CDAI ≤ 150, 5-Aminosalicylates (No), Corticosteroids (No), Immunomodulators (No), Biologics (No), Antibiotics (No), expenditure < RMB 8,000
OLS ordinal least squares, AIC Akaike information criterion, CDAI Crohn’s Disease Active Index

ISSN: 1477-7525