Table 7 Evaluation of reproducibility and responsiveness of EQ-5D-Y’s utility index and PROMIS-PAIS

Subsamples defined according to the EQ-VAS^a

EQ-5D-Y utility Index

 n

24

17

18

 1st administration, mean (SD)

0.94 (0.11)

0.98 (0.04)

0.90 (0.12)

 2nd administration, mean (SD)

0.95 (0.09)

0.95 (0.10)

0.94 (0.10)

 Change, mean (SD)

0.01 (0.08)

− 0.04 (0.09)

0.04 (0.11)

 P value

.50

.12

.18

 Effect size

0.14

0.68^d

 ICC^b

0.81

N/A^c

N/A^c

PROMIS-PAIS raw score^e

 n

19

12

15

 1st administration, mean (SD)

39.0 (7.4)

41.4 (7.8)

38.0 (6.6)

 2nd administration, mean (SD)

39.5 (9.8)

36.5 (5.8)

37.6 (6.0)

 Change, mean (SD)

− 0.5 (5.5)

5.0 (8.7)

0.4 (10.1)

 P value

.71

.07

.88

 Effect size

0.09

1.08^d

 ICC^b

0.89

N/A^c

N/A^c

Subsamples defined according to the ACQ^f

EQ-5D-Y utility Index

 n

29

6

16

 1st administration, mean (SD)

0.94 (0.10)

0.92 (0.15)

0.95 (0.08)

 2nd administration, mean (SD)

0.96 (0.09)

0.88 (0.14)

0.95 (0.08)

 Change, mean (SD)

0.02 (0.08)

− 0.04 (0.13)

0.00 (0.11)

 P value

.31

.50

.94

 Effect size

0.19

0.78^d

 ICC^b

0.79

N/A^c

N/A^c

EQ-VAS^a

 n

30

6

16

 1st administration, mean (SD)

88.9 (14.1)

78.5 (22.3)

80.4 (16.3)

 2nd administration, mean (SD)

90.8 (11.7)

83.0 (19.3)

83.1 (18.1)

 Change, mean (SD)

2.0 (12.5)

4.5 (24.0)

2.7 (20.2)

 P value

.40

.67

.59

 Effect size

0.16

1.15^d

 ICC^b

0.70

N/A^c

N/A^c

PROMIS-PAIS raw score^e

 n

25

6

11

 1st administration, mean (SD)

36.5 (4.0)

48.0 (10.1)

42.1 (9.0)

 2nd administration, mean (SD)

36.7 (5.2)

46.6 (11.8)

38.5 (7.1)

 Change, mean (SD)

− 0.2 (4.6)

1.4 (13.8)

3.7 (10.3)

 P value

.83

.82

.27

 Effect size

0.04

1.28^d

 ICC^b

0.68

N/A^c

N/A^c