Table 6 Comparison of Health-Related Quality of Life (HRQL) between known groups measured at baseline
% of participants reporting problems in each dimension (n of participants with problems/n of participants without problems) | EQ-5D-Y Utility Index | EQ-VASa | PROMIS PAISb raw Score | |||||
|---|---|---|---|---|---|---|---|---|
Mobility | Looking after myself | Doing usual activities | Having pain/discomfort | Feeling worried/sad/unhappy | Mean (SD) n = 116 | Mean (SD) n = 119 | Mean (SD) n = 75 | |
Asthma control—ACQc | ||||||||
Well controlled | 4.4% (3/65) | 1.5% (1/67) | 20.6% (14/54) | 14.7% (10/58) | 7.4% (5/63) | .94 (.12) | 88.2 (14.4) | 10.9 (4.4) |
Intermediate | 0.0% (0/23) | 4.3% (1/22) | 39.1% (9/14) | 21.7% (5/18) | 8.7% (2/21) | .91 (.11) | 78.6 (20.6) | 11.3 (3.3) |
Not well controlled | 13.0% (3/20) | 4.3% (1/22) | 45.8% (11/13) | 24.0% (6/19) | 8.0% (2/23) | .89 (.12) | 77.9 (18.5) | 16.2 (6.2) |
P value | .12 | .64 | .04 | .52 | .98 | .06 | < .006 | .002 |
ESd [95% CIe] | N/Af | N/Af | N/Af | N/Af | N/Af | − 0.38 [− 0.87 to 0.1] | 0.66 [0.19 to 1.13] | 1.11 [0.45 to 1.76] |
Asthmatic exacerbations (last 6 months) | ||||||||
No | 6.3% (4/60) | 1.5% (1/64) | 23.1% (15/50) | 13.6% (9/57) | 6.1% (4/62) | 0.94 (0.11) | 84.6 (18.3) | 11.3 (4.8) |
Yes | 3.8% (2/51) | 3.8% (2/50) | 35.8% (19/34) | 22.6% (12/41) | 9.4% (5/48) | 0.91 (0.12) | 84.0 (15.6) | 12.9 (5.0) |
P value | .55 | .43 | .13 | .20 | .49 | .12 | .46 | .15 |
ES [95% CI] | N/Af | N/Af | N/Af | N/Af | N/Af | − 0.24 [− 0.61 to 0.13] | 0.03 [− 0.33 to 0.4] | 0.35 [− 0.13 to 0.82] |
Frequency of SABAg use reported by patients (last 4 weeks) | ||||||||
Less than once per week | 4.3% (3/66) | 1.4% (1/69) | 18.6% (13/57) | 11.3% (8/63) | 5.6% (4/67) | 0.95 (0.09) | 88.4 (14.2) | 11.4 (4.9) |
Once or more per week | 6.7% (3/42) | 4.5% (2/42) | 46.7% (21/24) | 28.9% (13/32) | 11.1% (5/40) | 0.88 (0.14) | 77.2 (19.4) | 12.7 (5.0) |
P value | .59 | .31 | .001 | .02 | .28 | .004 | .001 | .27 |
ES [95% CI] | N/Af | N/Af | N/Af | N/Af | N/Af | − 0.59 [− 0.98 to − 0.2] | 0.68 [0.30 to 1.07] | 0.26 [− 0.21 to 0.73] |
Second-hand smoke exposure | ||||||||
Not exposed | 5.1% (4/75) | 1.3% (1/79) | 27.5% (22/58) | 17.3% (14/67) | 9.9% (8/73) | 0.92 (0.11) | 85.6 (15.4) | 11.6 (4.7) |
Exposed | 12.5% (2/14) | 13.3% (2/13) | 43.8% (7/9) | 37.5% (6/10) | 6.3% (1/15) | 0.87 (0.16) | 73.5 (19.7) | 13.7 (6.6) |
P value | .27 | .01 | .20 | .07 | .65 | .35 | .02 | .21 |
ES [95% CI] | N/Af | N/Af | N/Af | N/Af | N/Af | − 0.45 [− 1.01 to 0.1] | 0.75 [0.21 to 1.30] | 0.42 [− 0.23 to 1.07] |