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Table 4 Factors associated with HRQoL changes on the mental domain (SF-12 MCS) N = 126

From: Health-related quality of life in outpatients with substance use disorder: evolution over time and associated factors

Characteristics

Mean ± SD

Bivariable analysis

Multivariate analysis (R2 = 0.08)

T0

T1

T2

p value

p value

Effect size η2

Age

   

0.50

  

 ≤ 38.5

36.97 ± 10.59

42.38 ± 11.23

44.49 ± 11.44

   

 > 38.5

35.55 ± 11.77

41.19 ± 11.51

43.92 ± 11.23

   

Gender

   

0.44

  

 Male

36.46 ± 11.48

42.20 ± 11.55

43.93 ± 11.52

   

 Female

33.94 ± 8.07

39.17 ± 10.03

44.945 ± 10.36

   

Marital status

   

0.96

  

 Never married

36.13 ± 11.04

41.22 ± 11.02

44.09 ± 10.94

   

 Married/live with a partner

36.68 ± 10.12

42.48 ± 10.70

43.84 ± 11.37

   

 Separated/divorced/widowed

34.81 ± 12.15

42.08 ± 12.60

44.90 ± 12.16

   

Educational level

   

0.24

  

 Primary school

41.76 ± 12.68

43.62 ± 12.43

46.52 ± 13.90

   

 Secondary school

35.74 ± 10.52

41.67 ± 10.91

44.50 ± 10.89

   

 High school/university

34.08 ± 11.13

40.76 ± 12.51

41.51 ± 11.44

   

Occupational status

   

0.09

0.08

0.009

 Unemployed

37.06 ± 11.39

42.32 ± 11.37

45.27 ± 10.86

   

 Employed

34.04 ± 9.96

40.32 ± 11.23

42.23 ± 11.81

   

Type of dependence

   

0.88

  

 Alcohol dependence

35.66 ± 11.67

41.16 ± 11.96

44.39 ± 12.14

   

 Opioid dependence

36.13 ± 10.53

41.85 ± 10.98

43.99 ± 10.83

   

Duration of addiction (years)

   

0.70

  

 ≤ 13

36.08 ± 10.52

41.67 ± 10.88

45.06 ± 10.46

   

 > 13

36.08 ± 11.47

41.56 ± 11.70

43.35 ± 11.85

   

Comorbid axis I diagnosis

   

0.66

  

 Yes

37.02 ± 11.31

40.20 ± 11.35

45.85 ± 10.90

   

 No

35.35 ± 10.69

42.40 ± 11.26

43.15 ± 11.42

   

Origin of the care request

   

0.18

  

 Patient

36.64 ± 10.73

40.61 ± 11.58

43.29 ± 11.34

   

 Justice

38.25 ± 11.35

47.32 ± 10.57

47.23 ± 10.31

   

 Health practitioner

35.88 ± 12.04

42.53 ± 8.93

46.51 ± 11.48

   

Medication initiated during 6-month follow-up

  

0.004

0.009

0.021

 Yes

33.37 ± 10.02

39.67 ± 10.87

43.65 ± 11.57

   

 No

39.63 ± 11.25

44.77 ± 10.90

45.31 ± 10.36

   

Change in substance use behavior at 6 months

  

0.13

  

 Yes

34.69 ± 10.39

41.27 ± 10.82

44.53 ± 11.06

   

 No

41.97 ± 11.76

44.23 ± 12.43

43.46 ± 11.33

   

HADS anxiety

   

< 0.001

< 0.001

0.048

 < 8

43.65 ± 10.19

48.40 ± 10.42

47.22 ± 10.74

   

 ≥ 8

32.00 ± 9.08

38.66 ± 10.51

42.27 ± 11.40

   

HADS depression

   

< 0.001

< 0.001

0.034

 < 8

42.27 ± 10.85

45.17 ± 11.09

46.86 ± 10.32

   

 ≥ 8

30.93 ± 8.04

39.12 ± 10.99

41.90 ± 11.66

   
  1. SD standard deviation, HADS Hospital Anxiety and Depression Scale
  2. *Significant interaction with time for HADS depression (p < 0.05)