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Table 4 Summary of utility values included in economic evaluations for health states

From: Health-related quality of life in individuals with genital herpes: a systematic review

Lead author Neonatal HSV infection Genital herpes
Neonatal perspective Maternal perspective  
HSUV Duration (years) Probability of health state HSUV Duration (years) Probability of health state HSUV Duration (years) Probability of health state
Baker [17] No permanent impairment: 1 76.4 0.56       
Mild: 0.82 76.4 0.05 ·· ·· ·· ·· ·· ··
Moderate: 0.52 76.4 0.08 ·· ·· ·· ·· ·· ··
Severe: 0.16 20 0.14 ·· ·· ·· ·· ·· ··
Death: 0 . 0.17 ·· ·· ·· ·· ·· ··
Caviness [18] Normal: 1 77.8 ·· ·· ·· ·· ·· ·· ··
Mild: 0.82 77.8 Differs according to treatment arm, time and disease state (e.g., 12-month outcome with acyclovir therapy for disseminated disease: Normal: 0.28, Mild: 0.04, Moderate: 0.02, Severe: 0.13, Death: 0.53) ·· ·· ·· ·· ·· ··
Moderate: 0.52 77.8 ·· ·· ·· ·· ·· ··
Severe: 0.16 20 ·· ·· ·· ·· ·· ··
Death: 0 . ·· ·· ·· ·· ·· ··
Chatroux [4] Mild: 0.82 79.3 HSV-1: 0.69; HSV-2: 0.49 Mild: 0.94 54.8 HSV-1: 0.69; HSV-2: 0.49 ·· ·· ··
Moderate: 0.52 79.3 HSV-1: 0.01; HSV-2: 0.14 Moderate: 0.87 54.8 HSV-1: 0.01; HSV-2: 0.14 ·· ·· ··
Severe: 0.16 20 HSV-1: 0.02; HSV-2: 0.17 Severe: 0.76 54.8 HSV-1: 0.02; HSV-2: 0.17 ·· ·· ··
Death: 0 ·· HSV-1: 0.28; HSV-2: 0.2 Death: 0.92 54.8 HSV-1: 0.28; HSV-2: 0.2 ·· ·· ··
Little [19] Normal neonate: 1 77.2 # Caesarean delivery: 0.99 55.4 If lesions present at delivery: 1; if no lesions present: 0.244 ·· ·· ··
Moderate: 0.9 62.0 HSV-1: 0.01, HSV-2: 0.14 Having an impaired child: 0.81 55.4 Not reported ·· ·· ··
Severe: 0.3 28.7 HSV-1: 0.01, HSV-2: 0.17 Losing a child: 0.92 55.4 Not reported ·· ·· ··
Death: 0 ·· HSV-1: 0.28, HSV-2: 0.20 ·· ·· ·· ·· ·· ··
Smith [20] ·· ·· ·· ·· ·· ·· Stigma: 0.95 10 Unclear
·· ·· ·· ·· ·· ·· Symptomatic recurrence: 0.90 10  
Tuite [16] Normal/mild: 1 75 Unclear ·· ·· ·· ·· ·· ··
Moderate: 0.84 38 Unclear ·· ·· ·· ·· ·· ··
Severe: 0.41 38 Unclear ·· ·· ·· ·· ·· ··
Death: 0 ·· Unclear ·· ·· ·· ·· ·· ··
Thung [21] Normal: 1 76 Unclear ·· ·· ·· ·· ·· ··
Mild: 1 76 Unclear ·· ·· ·· ·· ·· ··
Moderate: 0.5 76 Unclear ·· ·· ·· ·· ·· ··
Severe: 0.1 76 Unclear ·· ·· ·· ·· ·· ··
Death: 0 . Unclear ·· ·· ·· ·· ·· ··
  1. HSUV health-state utility values; HSV Herpes simplex virus; QALY quality-adjusted life years