Skip to main content

Table 3 Overall outcomes by tumor location

From: Depression, anxiety and health-related quality of life in paediatric intracranial germ cell tumor survivors

  Suprasellar
Mean (SD)
Pineal
Mean (SD)
Basal Ganglia
Mean (SD)
Bifocal Aa
Mean (SD)
Bifocal Ba
Mean (SD)
Dissemination
Mean (SD)
P
PedsQL (PPR)
 Participants 40 37 27 25 5 18  
 Total 71.55 (17.14) 77.00 (15.68) 68.84 (20.11) 77.22 (14.19) 50.87 (11.23) 74.09 (14.45) 0.014
 Physical 74.30 (20.75) 83.28 (16.24) 71.30 (20.38) 82.13 (16.23) 54.38 (23.66) 75.52 (13.82) 0.005
 Psychosocial summary emotional 70.08 (17.30) 73.65 (17.36) 67.53 (21.20) 74.60 (15.53) 49.00 (10.51) 73.33 (16.40) 0.053
 Social 70.25 (17.36) 76.62 (16.83) 79.26 (16.45) 77.60 (15.15) 62.00 (10.37) 79.17 (16.74) 0.074
 School/work 76.00 (21.55) 76.62 (20.85) 65.93 (28.89) 81.60 (20.75) 55.00 (17.68) 79.44 (17.31) 0.044
  64.00 (21.79) 67.70 (19.35) 57.41 (25.92) 64.60 (18.54) 30.00 (19.69) 61.39 (22.48) 0.011
PedsQL (CSR)
 Participants 37 28 22 21 2 14  
 Total 77.41 (16.22) 79.54 (13.91) 69.17 (23.61) 72.10 (14.12) 36.96 (4.61) 76.01 (16.16) 0.009
 Physical 77.70 (18.77) 84.15 (11.87) 70.45 (25.24) 77.23 (16.24) 32.81 (2.21) 78.57 (15.10) 0.003
 Psychosocial summary emotional 77.25 (16.50) 77.08 (16.26) 68.48 (24.30) 69.37 (15.51) 39.17 (5.89) 74.64 (17.30) 0.030
 Social 77.16 (15.66) 78.39 (19.25) 78.41 (19.30) 69.76 (19.78) 62.50 (17.68) 73.93 (18.83) 0.456
 School/work 82.84 (17.93) 82.50 (17.02) 68.64 (30.79) 75.00 (21.68) 30.00 (7.07) 80.71 (18.28) 0.004
  71.76 (20.49) 70.36 (18.35) 58.41 (27.92) 63.33 (16.53) 25.00 (7.07) 69.29 (22.61) 0.015
Depression/anxiety
 Participants 28 22 14 15 2 4  
 Child depression (CDI) 6.32 (4.60) 7.32 (5.62) 8.57 (6.32) 8.20 (4.74) 18.00 (1.41) 5.75 (3.40) 0.060
 Participants 31 27 17 17 1 5  
 Child anxiety (SCARED) 14.42 (11.35) 18.63 (11.72) 8.00 (7.31) 12.24 (9.55) 7.00 11.80 (6.54) 0.039
 Participants 6 8 7 10 1 10  
 Adult depression (SCL-90) 1.56 (0.47) 1.47 (0.51) 1.11 (0.95) 4.97 (4.96) 2.31 1.32 (0.72) 0.022
 Adult anxiety (SCL-90) 1.35 (0.27) 1.35 (0.25) 1.16 (0.84) 2.97 (2.68) 2.40 1.20 (0.39) 0.062
  1. Bold: p < 0.05
  2. aBifocal origins A: pineal and suprasellar regions. Bifocal origins B: suprasellar region and basal ganglia regions