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Table 3 Overall outcomes by tumor location

From: Depression, anxiety and health-related quality of life in paediatric intracranial germ cell tumor survivors

 

Suprasellar

Mean (SD)

Pineal

Mean (SD)

Basal Ganglia

Mean (SD)

Bifocal Aa

Mean (SD)

Bifocal Ba

Mean (SD)

Dissemination

Mean (SD)

P

PedsQL (PPR)

 Participants

40

37

27

25

5

18

 

 Total

71.55 (17.14)

77.00 (15.68)

68.84 (20.11)

77.22 (14.19)

50.87 (11.23)

74.09 (14.45)

0.014

 Physical

74.30 (20.75)

83.28 (16.24)

71.30 (20.38)

82.13 (16.23)

54.38 (23.66)

75.52 (13.82)

0.005

 Psychosocial summary emotional

70.08 (17.30)

73.65 (17.36)

67.53 (21.20)

74.60 (15.53)

49.00 (10.51)

73.33 (16.40)

0.053

 Social

70.25 (17.36)

76.62 (16.83)

79.26 (16.45)

77.60 (15.15)

62.00 (10.37)

79.17 (16.74)

0.074

 School/work

76.00 (21.55)

76.62 (20.85)

65.93 (28.89)

81.60 (20.75)

55.00 (17.68)

79.44 (17.31)

0.044

 

64.00 (21.79)

67.70 (19.35)

57.41 (25.92)

64.60 (18.54)

30.00 (19.69)

61.39 (22.48)

0.011

PedsQL (CSR)

 Participants

37

28

22

21

2

14

 

 Total

77.41 (16.22)

79.54 (13.91)

69.17 (23.61)

72.10 (14.12)

36.96 (4.61)

76.01 (16.16)

0.009

 Physical

77.70 (18.77)

84.15 (11.87)

70.45 (25.24)

77.23 (16.24)

32.81 (2.21)

78.57 (15.10)

0.003

 Psychosocial summary emotional

77.25 (16.50)

77.08 (16.26)

68.48 (24.30)

69.37 (15.51)

39.17 (5.89)

74.64 (17.30)

0.030

 Social

77.16 (15.66)

78.39 (19.25)

78.41 (19.30)

69.76 (19.78)

62.50 (17.68)

73.93 (18.83)

0.456

 School/work

82.84 (17.93)

82.50 (17.02)

68.64 (30.79)

75.00 (21.68)

30.00 (7.07)

80.71 (18.28)

0.004

 

71.76 (20.49)

70.36 (18.35)

58.41 (27.92)

63.33 (16.53)

25.00 (7.07)

69.29 (22.61)

0.015

Depression/anxiety

 Participants

28

22

14

15

2

4

 

 Child depression (CDI)

6.32 (4.60)

7.32 (5.62)

8.57 (6.32)

8.20 (4.74)

18.00 (1.41)

5.75 (3.40)

0.060

 Participants

31

27

17

17

1

5

 

 Child anxiety (SCARED)

14.42 (11.35)

18.63 (11.72)

8.00 (7.31)

12.24 (9.55)

7.00

11.80 (6.54)

0.039

 Participants

6

8

7

10

1

10

 

 Adult depression (SCL-90)

1.56 (0.47)

1.47 (0.51)

1.11 (0.95)

4.97 (4.96)

2.31

1.32 (0.72)

0.022

 Adult anxiety (SCL-90)

1.35 (0.27)

1.35 (0.25)

1.16 (0.84)

2.97 (2.68)

2.40

1.20 (0.39)

0.062

  1. Bold: p < 0.05
  2. aBifocal origins A: pineal and suprasellar regions. Bifocal origins B: suprasellar region and basal ganglia regions