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Table 2 Overall outcomes by tumor recurrence

From: Depression, anxiety and health-related quality of life in paediatric intracranial germ cell tumor survivors

  Non-recurrence
Mean (SD)
Recurrence
Mean (SD)
P
PedsQL (PPR)
 Participants 152 18  
 Total 72.95 (17.03) 61.29 (17.89) 0.007
 Physical 76.73 (19.04) 64.24 (25.77) 0.042
 Psychosocial summary emotional 70.93 (17.92) 59.72 (17.66) 0.013
 Social 75.39 (16.77) 61.94 (19.64) 0.006
 School/work 75.00 (22.72) 66.39 (21.54) 0.088
  62.40 (22.29) 50.83 (21.44) 0.024
PedsQL (CSR)
 Participants 124 15  
 Total 74.72 (17.67) 62.97 (17.27) 0.013
 Physical 77.17 (19.01) 66.46 (23.75) 0.095
 Psychosocial summary emotional 73.41 (18.53) 61.11 (15.82) 0.009
 Social 75.81 (18.25) 60.67 (18.11) 0.006
 School/work 77.82 (22.34) 68.67 (19.22) 0.050
  66.61 (21.97) 54.00 (16.60) 0.014
Depression/anxiety
 Participants 85 8  
 Child depression (CDI) 7.53 (5.34) 15.63 (11.16) 0.034
 Participants 98 9  
 Child anxiety (SCARED) 13.88 (10.77) 23.22 (15.71) 0.061
 Participants 42 9  
 Adult depression (SCL-90) 2.24 (2.85) 1.79 (0.82) 0.323
 Adult anxiety (SCL-90) 1.69 (1.51) 1.51 (0.86) 0.725
  1. Bold: p < 0.05
  2. PedsQL, Pediatric Quality of Life Inventory 4.0 Generic Core Scales; PPR, parent proxy report; CSR, child self-report