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Table 5 Change in electronic EQ-5D scores from baseline to 3 months follow up by GRS groups, Aug 2018 – Mar 2019 (N = 99)

From: A pilot study on the validity and psychometric properties of the electronic EQ-5D-5L in routine clinical practice

 

EQ-5D Utility score (mean ± SD, n)

EQ-VAS score (mean ± SD, n)

Change in EQ-5D Dimension level with limitation from baseline to 3-month (%)

Baseline

3-month

Difference

p value*

Baseline

3-month

Difference

p value*

Mobility

Self-care

Usual Activities

Pain/Discomfort

Depression/Anxiety

GRS Group

             

GRS Better

0.58 ± 0.28 (20)

0.76 ± 0.26 (20)

0.18 ± 0.18 (20)

< 0.001

65.90 ± 18.13 (20)

76.65 ± 14.00 (20)

10.75 ± 15.33 (20)

0.005

− 15.0% (20)

− 15.0% (20)

− 15.0% (20)

− 40% (20)

− 20% (20)

Effect size

  

0.666

   

0.664

      

GRS Same

0.71 ± 0.23 (44)

0.79 ± 0.17 (44)

0.08 ± 0.17 (44)

0.002

74.59 ± 15.22 (44)

76.32 ± 11.54 (44)

1.73 ± 12.60 (44)

0.368

− 9.1% (44)

− 2.3% (44)

− 2.3% (44)

− 13.6% (44)

0% (44)

Effect size

  

0.396

   

0.128

      

GRS Worse

0.61 ± 0.27 (35)

0.53 ± 0.30 (35)

− 0.08 ± 0.28 (35)

0.092

67.37 ± 15.22 (35)

62.43 ± 18.08 (35)

− 4.94 ± 18.31 (35)

0.120

14.3% (35)

2.9% (35)

8.6% (35)

22.9% (35)

2.9% (35)

Effect size

  

0.280

   

0.296

 

p  value#

         

< 0.001

< 0.001

< 0.001

0.021

< 0.001

Overall

0.65 ± 0.26 (99)

0.69 ± 0.27 (99)

0.04 ± 0.24 (99)

0.074

70.28 ± 16.33 (99)

71.47 ± 15.97 (99)

1.19 ± 16.24 (99)

0.467

− 2.2% (99)

− 2.0% (99)

− 1.0% (99)

− 6.1% (99)

− 3.0% (99)

Effect size

  

0.151

   

0.074

      

Mean GRS†

  

0.589**

   

0.495**

      
  1. GRS, global rating scale
  2. *Difference between baseline and 3-month EQ-5D Utility and EQ-5D VAS scores tested by paired t-tests
  3. #EQ-5D-5L dimension responses of moderate, severe and very severe were grouped into the ‘with limitation’ category; difference in proportions among GRS groups tested by Chi-square tests
  4. Correlation between mean GRS score and EQ-5D-5L utility or VAS score, tested by Spearman correlation; **p < 0.001