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Table 4 Linear regressions on sociodemographic, CDC healthy-days and employment associated with WHOQOL-BREF scores

From: Quality of life and challenges experienced by the surviving adults with transfusion dependent thalassaemia in Malaysia: a cross sectional study

Factors Simple linear regression (coefficient (95% CI)) Multiple linear regressiona (coefficient (95% CI))
Physical health
 Education (higher) 5.17 (1.01, 9.34)* 2.14 (− 2.35, 6.64)
 Hospital visits (more frequent)  − 3.78 (− 6.54, − 1.02)*  − 0.70 (− 3.61, 2.20)
 Monthly income (higher) 3.60 (1.05, 6.15)* 4.38 (1.11, 7.66)*
 Days when activities were affected by physical and or mental issues (more days)  − 1.58 (− 2.26, − 0.90)*  − 1.98 (− 2.92, − 1.05)*
 Days affected by physical issues (more days)  − 1.13 (− 1.92, − 0.33)*  − 0.39 (− 1.42, 0.64)
 Days affected by mental issues (more days)  − 1.02, (− 1.7, − 0.35)*  − 0.25 (− 1.02, 0.53)
Psychological health
 Malay ethnic 4.01 (1.15, 6.87)* 4.54 (0.83, 8.24)*
 Presence of other comorbidities  − 5.40 (− 9.98, − 0.82)*  − 5.43 (− 10.88, 0.02)
 Days when activities were affected by physical and or mental issues (more days)  − 1.03 (− 1.75, − 0.32)*  − 1.50 (− 2.55, − 0.44)*
 Days affected by mental issues (more days)  − 1.04 (− 1.72, − 0.35)*  − 0.50 (− 1.37, 0.37)
Social relationship
 Education (higher) 5.26 (0.92, 9.61)* 3.51 (− 1.36, 8.37)
 Marital status (being single)  − 7.58 (− 13.15, − 2.00)*  − 12.27 (− 18.75, − 5.77)*
 Monthly income (higher) 3.97 (1.38, 6.56)* 3.64 (0.14, 7.14)*
 Days affected by mental issues (more days)  − 1.10 (− 1.78, − 0.43)*  − 0.86 (− 1.68, − 0.05)*
Environmental health
 Education (higher) 7.01 (2.49, 11.53)* 4.90 (0.01, 9.90)
 Malay ethnic 3.23 (0.11, 6.36)* 4.54 (0.89, 8.18)*
 Hospital visits (more frequent)  − 3.57 (− 6.62, − 0.53)*  − 0.70 (− 3.91, 2.50)
 Presence of other comorbidities  − 6.34 (− 11.23, − 1.44)*  − 5.11 (− 10.45, 0.22)
 Days affected by mental issues (more days)  − 0.97 (− 1.72, − 0.23)*  − 0.48 (− 1.34, 0.37)
 Currently have a job  − 4.72 (− 9.74, 0.31)*  − 2.68 (− 9.08, 3.72)
 Monthly income (higher) 1.36 (− 1.47, 4.20) 3.75 (0.14, 7.37)*
  1. Factors which have no significant association in both simple and multiple linear regression were not displayed for the specified domain
  2. *p < 0.05
  3. aAdjusted according to gender, ethnicity, education, marital status, age at first diagnosis and transfusion, type of iron chelation, frequency of hospital visits, presence of other comorbidities, employment status (monthly income, currently have a job) and factors in CDC healthy-days (days affected by physical issues, days affected by mental issues, days when activities were affected by physical and or mental issues)