Variable | Total (%) |
---|---|
Patients that presented AEs, n (%) | |
Yes | 142 (77.2) |
No | 42 (22.8) |
Total number of AEs | 260 |
Type of AEs, n (%) | |
Asthenia | 35 (13.5) |
Pruritus | 29 (11.2) |
Xerosis | 24 (9.2) |
Palmar-plantar erythrodysesthesia (PPE) | 24 (9.2) |
Alopecia | 21 (8.0) |
Neurotoxicity | 20 (7.7) |
Papulopustular rash | 17 (6.5) |
Gastrointestinal toxicity | 16 (6.2) |
Ungual apparatus alterations | 13 (5.0) |
Pigmentary changes | 13 (5.0) |
Others* | 48 (18.5) |
Number of AEs per patient, n(%) | |
Patients with one AE | 126 (68.5) |
Patients with two or more AEs | 58 (31.5) |
Severity of AEs, n (%) | |
Grade 1 | 180 (69.2) |
Grade 2 | 67 (25.8) |
Grade 3 | 13 (5.0) |
Grade 4 | – |
Treatment interruption due to AEs | |
Yes | 20 (10.9) |
No | 164 (89.1) |