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Table 4 DIF analyses by Asian: baseline data* **

From: No impact of Asian ethnicity on EORTC QLQ-C30 scores: Group differences and differential item functioning in paroxysmal nocturnal hemoglobinuria

Item no

Item content

Domain

Test of uniform DIF

Test of non-uniform DIF

Test of Uniform and non-uniform DIF

LR Chi2

P-value

Change in R2

DIF size

"Favored" group

Odds Ratio

LR Chi2

P-value

Change in R2

DIF size

LR Chi2

P-value

Change in R2

DIF size

eortc29

29. How would you rate your overall health during the past week?

Global

5.56

0.018

0.004

Negligible

Non-Asian

0.51

NS

NS

NS

NS

NS

NS

NS

NS

eortc30

30. How would you rate your overall quality of life during the past week?

Global

4.94

0.026

0.003

Negligible

Asian

1.90

NS

NS

NS

NS

NS

NS

NS

NS

eortc01

1. Do you have any trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase?

Physical

6.04

0.014

0.006

Negligible

Non-Asian

0.56

NS

NS

NS

NS

7.47

0.024

0.007

Negligible

eortc02

2. Do you have any trouble taking a long walk?

Physical

6.99

0.008

0.006

Negligible

Asian

1.91

NS

NS

NS

NS

9.01

0.011

0.008

Negligible

eortc03

3. Do you have any trouble taking a short walk outside of the house?

Physical

NS

NS

NS

NS

NS

NS

6.29

0.012

0.010

Negligible

6.75

0.034

0.011

Negligible

eortc04

4. Do you need to stay in bed or a chair during the day?

Physical

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc05

5. Do you need help with eating, dressing, washing yourself or using the toilet?

Physical

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc06

6. Were you limited in doing either your work or other daily activities?

Role

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc07

7. Were you limited in pursuing your hobbies or other leisure time activities?

Role

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc21

21. Did you feel tense?

Emotional

7.10

0.008

0.008

Negligible

Non-Asian

0.49

NS

NS

NS

NS

10.28

0.006

0.012

Negligible

eortc22

22. Did you worry?

Emotional

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc23

23. Did you feel irritable?

Emotional

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc24

24. Did you feel depressed?

Emotional

9.83

0.002

0.011

Negligible

Asian

2.26

NS

NS

NS

NS

13.57

0.001

0.015

Negligible

eortc20

20. Have you had difficulty in concentrating on things, like reading a newspaper or watching television?

Cognitive

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc25

25. Have you had difficulty remembering things?

Cognitive

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc26

26. Has your physical condition or medical treatment interfered with your family life?

Social

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc27

27. Has your physical condition or medical treatment interfered with your social activities?

Social

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc10

10. Did you need to rest?

Fatigue

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc12

12. Have you felt weak?

Fatigue

14.76

0.000

0.014

Negligible

Asian

2.84

NS

NS

NS

NS

14.84

0.001

0.014

Negligible

eortc18

18. Were you tired?

Fatigue

4.77

0.029

0.005

Negligible

Non-Asian

0.54

NS

NS

NS

NS

NS

NS

NS

NS

eortc14

14. Have you felt nauseated?

Nausea

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc15

15. Have you vomited?

Nausea

4.41

0.036

0.018

Negligible

Asian

3.52

NS

NS

NS

NS

NS

NS

NS

NS

eortc09

9. Have you had pain?

Pain

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

eortc19

19. Did pain interfere with your daily activities?

Pain

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

NS

  1. *NS = Not significant, **"R2" refers to pseudo-R2