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Table 3 Multiple linear regression analysis of HRQoL of patients with stoma with/without colon resection at baseline and at 6-month follow-up, according to planned stoma before operation, adjusted for age, sex, BMI, smoking, ASA classification, acute/elective surgery and TNM stage

From: Risk factors for poor health-related quality of life in patients with colon cancer include stoma and smoking habits

Scale Baseline 6-month follow-up
Stoma with resection (n = 89)a Stoma without resection (n = 14)a Stoma with resection (n = 68)a Stoma without resection (n = 4)a
β P β P R2 β P β P R2
Global health status − 7.1 0.025 − 24.6 < 0.001 0.114 1.0 0.782 − 27.0 0.027 0.072
Functional scales           
Physical function − 4.2 0.115 − 18.9 0.001 0.272 − 3.2 0.300 − 11.4 0.269 0.135
Role function − 9.6 0.038 − 33.2 0.001 0.123 0.08 0.986 − 22.5 0.209 0.056
Emotional function − 9.8 0.001 − 13.6 0.047 0.094 − 5.9 0.102 − 22.8 0.057 0.114
Cognitive function − 2.1 0.467 − 2.7 0.679 0.024 − 5.5 0.121 − 24.6 0.037 0.073
Social function − 8.5 0.015 − 11.3 0.157 0.058 − 7.9 0.074 − 46.5 0.002 0.130
Symptom scales/items           
Fatigue 8.4 0.018 7.6 0.337 0.079 3.8 0.337 12.4 0.349 0.076
Nausea/vomiting 4.4 0.054 6.4 0.209 0.069 2.2 0.317 30.8 < 0.001 0.173
Pain 7.8 0.044 22.5 0.010 0.073 3.2 0.439 47.7 < 0.001 0.103
Dyspnoea − 0.9 0.807 0.02 0.998 0.151 − 4.1 0.326 − 1.9 0.890 0.091
Insomnia 3.4 0.443 9.3 0.349 0.014 4.3 0.404 16.1 0.342 0.065
Appetite loss 14.0 0.002 40.5 < 0.001 0.122 − 0.7 0.874 33.5 0.015 0.074
Constipation 1.2 0.749 − 5.6 0.513 0.037 − 7.9 0.017 18.5 0.083 0.074
Diarrhoea 2.7 0.551 33.4 0.001 0.048 2.4 0.570 10.5 0.444 0.080
Financial difficulties 1.7 0.538 2.2 0.721 0.061 2.1 0.588 17.1 0.180 0.134
  1. The highest observed Variance Inflation Factors were 1.404 at baseline and 1.390 at 6-month follow-up, Significant P values are given in bold
  2. ASA American Society of Anesthesiologists, BMI body mass index, HRQoL health-related quality of life, TNM tumour–node–metastasis
  3. aReference category: No stoma