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Table 3 Multiple linear regression analysis of HRQoL of patients with stoma with/without colon resection at baseline and at 6-month follow-up, according to planned stoma before operation, adjusted for age, sex, BMI, smoking, ASA classification, acute/elective surgery and TNM stage

From: Risk factors for poor health-related quality of life in patients with colon cancer include stoma and smoking habits

Scale

Baseline

6-month follow-up

Stoma with resection (n = 89)a

Stoma without resection (n = 14)a

Stoma with resection (n = 68)a

Stoma without resection (n = 4)a

β

P

β

P

R2

β

P

β

P

R2

Global health status

− 7.1

0.025

− 24.6

< 0.001

0.114

1.0

0.782

− 27.0

0.027

0.072

Functional scales

          

Physical function

− 4.2

0.115

− 18.9

0.001

0.272

− 3.2

0.300

− 11.4

0.269

0.135

Role function

− 9.6

0.038

− 33.2

0.001

0.123

0.08

0.986

− 22.5

0.209

0.056

Emotional function

− 9.8

0.001

− 13.6

0.047

0.094

− 5.9

0.102

− 22.8

0.057

0.114

Cognitive function

− 2.1

0.467

− 2.7

0.679

0.024

− 5.5

0.121

− 24.6

0.037

0.073

Social function

− 8.5

0.015

− 11.3

0.157

0.058

− 7.9

0.074

− 46.5

0.002

0.130

Symptom scales/items

          

Fatigue

8.4

0.018

7.6

0.337

0.079

3.8

0.337

12.4

0.349

0.076

Nausea/vomiting

4.4

0.054

6.4

0.209

0.069

2.2

0.317

30.8

< 0.001

0.173

Pain

7.8

0.044

22.5

0.010

0.073

3.2

0.439

47.7

< 0.001

0.103

Dyspnoea

− 0.9

0.807

0.02

0.998

0.151

− 4.1

0.326

− 1.9

0.890

0.091

Insomnia

3.4

0.443

9.3

0.349

0.014

4.3

0.404

16.1

0.342

0.065

Appetite loss

14.0

0.002

40.5

< 0.001

0.122

− 0.7

0.874

33.5

0.015

0.074

Constipation

1.2

0.749

− 5.6

0.513

0.037

− 7.9

0.017

18.5

0.083

0.074

Diarrhoea

2.7

0.551

33.4

0.001

0.048

2.4

0.570

10.5

0.444

0.080

Financial difficulties

1.7

0.538

2.2

0.721

0.061

2.1

0.588

17.1

0.180

0.134

  1. The highest observed Variance Inflation Factors were 1.404 at baseline and 1.390 at 6-month follow-up, Significant P values are given in bold
  2. ASA American Society of Anesthesiologists, BMI body mass index, HRQoL health-related quality of life, TNM tumour–node–metastasis
  3. aReference category: No stoma