Skip to main content

Table 1 Mean scores, mean change, and estimated 1-year follow-up changes, and floor and ceiling scores

From: Patient-reported outcomes in coronary artery disease: the relationship between the standard, disease-specific set by the International Consortium for Health Outcomes Measurement (ICHOM) and the generic health-related quality of life instrument 15D

Instrument score

BL mean value (95% CI)

1 year follow-up change (95% CI)

Floor, n (%)

Ceiling, n (%)

Mean

OMTa

PCIa

CABGa

BL

1 yr

BL

1 yr

SAQ-7

63.3 (60.8–65.8)

16.4 (14.0–18.9)

11.4 (9.1–15.9)

17.6 (14.2–19.6)

30.2 (21.1–35.0)

1 (0.4)

1 (0.4)

18 (6.5)

63 (22.6)

SAQ-PL

76.5 (73.8–79.2)

5.1 (2.7–7.6)

3.7 (− 1.0 to 6.6)

5.0 (2.8–8.6)

10.0 (3.1–18.2)

2 (0.8)

2 (0.7)

66 (25.8)

92 (37.1)

SAQ-AF

65.6 (62.6–68.7)

17.8 (14.9–20.7)

12.4 (10.7–18.1)

19.7 (15.3–21.2)

27.9 (20.0–24.9)

3 (1.1)

2 (0.7)

38 (13.7)

125 (44.8)

SAQ-QL

48.8 (45.4–52.2)

25.7 (21.8–29.6)

18.0 (15.5–25.6)

27.3 (22.3–30.2)

47.4 (29.8–50.7)

13 (4.7)

3 (1.1)

25 (9.1)

107 (38.5)

RDS

1.9 (1.7–2.0)

0.5 (0.4–0.6)

0.2 (0.1–0.4)

0.6 (0.4–0.7)

1.0 (0.6–1.4)

27 (9.7)

19 (6.8)

42 (15.1)

83 (29.7)

PHQ-2

1.0 (0.8–1.1)

0.1 (0.0–0.3)

0.1 (− 0.2 to 0.2)

0.1 (0.0–0.3)

0.5 (0.0–0.9)

5 (1.8)

5 (1.8)

143 (51.3)

167 (59.9)

15D

0.818 (0.806–0.830)

0.024 (0.016–0.032)

0.005 (− 0.009 to 0.017)

0.028 (0.019–0.039)

0.074 (0.051–0.104)

1 (0.4)

1 (0.4)

3 (1.1)

3 (1.1)

15D dimension values

         

Mobility

0.817 (0.797–0.837)

0.030 (0.010–0.049)

0.015 (− 0.015 to 0.045)

0.033 (0.009–0.057)

0.077 (0.014–0.140)

21 (7.5)

3 (1.1)

119 (42.7)

150 (53.8)

Vision

0.917 (0.899–0.934)

0.010 (− 0.010 to 0.029)

0.010 (− 0.016 to 0.037)

0.011 (− 0.011 to 0.032)

 − 0.014 (− 0.068 to 0.041)

5 (1.8)

6 (2.2)

196 (70.3)

205 (73.5)

Hearing

0.895 (0.875–0.915)

0.005 (− 0.011 to 0.021)

 − 0.003 (− 0.027 to 0.021)

0.008 (− 0.012 to 0.027)

0.018 (− 0.032 to 0.067)

1 (0.4)

21 (7.5)

189 (67.7)

191 (68.5)

Breathing

0.657 (0.630–0.684)

0.105 (0.079–0.130)

0.071 (0.036–0.107)

0.104 (0.075–0.133)

0.241 (0.168–0.315)

2 (0.7)

1 (0.4)

60 (21.5)

110 (39.4)

Sleeping

0.760 (0.736–0.785)

0.019 (− 0.001 to 0.039)

0.003 (− 0.026 to 0.032)

0.020 (− 0.003 to 0.043)

0.081 (0.023–0.140)

30 (7.2)

1 (0.4)

86 (30.8)

89 (31.9)

Eating

0.987 (0.980–0.995)

0.006 (0.000–0.013)

0.003 (− 0.005 to 0.010)

0.007 (0.001–0.013)

0.013 (− 0.003 to 0.028)

10 (3.6)

5 (1.8)

269 (96.4)

374 (89.2)

Speech

0.959 (0.946–0.972)

 − 0.005 (− 0.017 to 0.007)

 − 0.020 (− 0.038 to [− 0.002])

0.002 (− 0.013 to 0.016)

0.006 (− 0.030 to 0.043)

2 (0.7)

2 (0.7)

242 (86.7)

237 (84.9)

Excretion

0.878 (0.815–0.860)

 − 0.013 (− 0.037 to 0.010)

 − 0.048 (− 0.082 to [− 0.014])

0.007 (− 0.020 to 0.034)

0.023 (− 0.065 to 0.072)

1 (0.4)

20 (7.2)

151 (54.1)

142 (50.9)

Usual activities

0.758 (0.732–0.783)

0.030 (0.007–0.053)

 − 0.011 (− 0.044 to 0.023)

0.040 (0.013–0.067)

0.130 (0.062–0.199)

6 (2.2)

5 (1.8)

97 (34.8)

116 (41.6)

Mental functions

0.876 (0.855–0.897)

 − 0.013 (− 0.032 to 0.005)

 − 0.040 (− 0.069 to [− 0.011])

0.003 (− 0.020 to 0.027)

0.003 (− 0.056 to 0.062)

1 (0.4)

1 (0.4)

185 (66.3)

179 (64.2)

Discomfort and symptoms

0.671 (0.645–0.697)

0.051 (0.026–0.075)

0.025 (− 0.011 to 0.060)

0.056 (0.028–0.085)

0.140 (0.066–0.215)

3 (1.1)

14 (5.0)

49 (17.6)

77 (27.6)

Depression

0.890 (0.873–0.907)

0.010 (− 0.005 to 0.025)

 − 0.007 (− 0.030 to 0.015)

0.013 (− 0.004 to 0.031)

0.069 (0.024–0.115)

1 (0.4)

3 (1.1)

162 (58.1)

177 (63.4)

Distress

0.870 (0.851–0.888)

0.024 (0.006–0.042)

0.011 (− 0.014 to 0.036)

0.025 (0.005–0.045)

0.072 (0.020–0.123)

1 (0.4)

10 (3.6)

159 (57.0)

180 (64.5)

Vitality

0.734 (0.715–0.753)

0.054 (0.035–0.073)

0.026 (− 0.002 to 0.053)

0.058 (0.036–0.081)

0.145 (0.088–0.202)

5 (1.8)

8 (2.9)

42 (15.1)

76 (27.2)

Sexual activity

0.671 (0.638–0.705)

0.026 (0.001–0.052)

 − 0.001 (− 0.039 to 0.038)

0.026 (− 0.005 to 0.057)

0.148 (0.068–0.227)

18 (6.8)

20 (7.2)

92 (33.0)

102 (36.6)

  1. BL, Baseline; CABG, coronary artery bypass grafting; CI, confidence interval; OMT, optimal medical therapy; PCI, percutaneous coronary intervention; PHQ-2, two-item Patient Health Questionnaire; RDS, Rose Dyspnea Scale; SAQ-AF, Seattle Angina Questionnaire Angina Frequency; SAQ-PL, Seattle Angina Physical Limitation; SAQ-QL, Seattle Angina Quality of Life; SAQ-7, Seattle Angina Questionnaire short-form; SD, Standard Deviation; 1 yr, one-year; 15D, 15-dimensional instrument
  2. aAdjusted for baseline scores