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Table 1 Mean scores, mean change, and estimated 1-year follow-up changes, and floor and ceiling scores

From: Patient-reported outcomes in coronary artery disease: the relationship between the standard, disease-specific set by the International Consortium for Health Outcomes Measurement (ICHOM) and the generic health-related quality of life instrument 15D

Instrument score BL mean value (95% CI) 1 year follow-up change (95% CI) Floor, n (%) Ceiling, n (%)
Mean OMTa PCIa CABGa BL 1 yr BL 1 yr
SAQ-7 63.3 (60.8–65.8) 16.4 (14.0–18.9) 11.4 (9.1–15.9) 17.6 (14.2–19.6) 30.2 (21.1–35.0) 1 (0.4) 1 (0.4) 18 (6.5) 63 (22.6)
SAQ-PL 76.5 (73.8–79.2) 5.1 (2.7–7.6) 3.7 (− 1.0 to 6.6) 5.0 (2.8–8.6) 10.0 (3.1–18.2) 2 (0.8) 2 (0.7) 66 (25.8) 92 (37.1)
SAQ-AF 65.6 (62.6–68.7) 17.8 (14.9–20.7) 12.4 (10.7–18.1) 19.7 (15.3–21.2) 27.9 (20.0–24.9) 3 (1.1) 2 (0.7) 38 (13.7) 125 (44.8)
SAQ-QL 48.8 (45.4–52.2) 25.7 (21.8–29.6) 18.0 (15.5–25.6) 27.3 (22.3–30.2) 47.4 (29.8–50.7) 13 (4.7) 3 (1.1) 25 (9.1) 107 (38.5)
RDS 1.9 (1.7–2.0) 0.5 (0.4–0.6) 0.2 (0.1–0.4) 0.6 (0.4–0.7) 1.0 (0.6–1.4) 27 (9.7) 19 (6.8) 42 (15.1) 83 (29.7)
PHQ-2 1.0 (0.8–1.1) 0.1 (0.0–0.3) 0.1 (− 0.2 to 0.2) 0.1 (0.0–0.3) 0.5 (0.0–0.9) 5 (1.8) 5 (1.8) 143 (51.3) 167 (59.9)
15D 0.818 (0.806–0.830) 0.024 (0.016–0.032) 0.005 (− 0.009 to 0.017) 0.028 (0.019–0.039) 0.074 (0.051–0.104) 1 (0.4) 1 (0.4) 3 (1.1) 3 (1.1)
15D dimension values          
Mobility 0.817 (0.797–0.837) 0.030 (0.010–0.049) 0.015 (− 0.015 to 0.045) 0.033 (0.009–0.057) 0.077 (0.014–0.140) 21 (7.5) 3 (1.1) 119 (42.7) 150 (53.8)
Vision 0.917 (0.899–0.934) 0.010 (− 0.010 to 0.029) 0.010 (− 0.016 to 0.037) 0.011 (− 0.011 to 0.032)  − 0.014 (− 0.068 to 0.041) 5 (1.8) 6 (2.2) 196 (70.3) 205 (73.5)
Hearing 0.895 (0.875–0.915) 0.005 (− 0.011 to 0.021)  − 0.003 (− 0.027 to 0.021) 0.008 (− 0.012 to 0.027) 0.018 (− 0.032 to 0.067) 1 (0.4) 21 (7.5) 189 (67.7) 191 (68.5)
Breathing 0.657 (0.630–0.684) 0.105 (0.079–0.130) 0.071 (0.036–0.107) 0.104 (0.075–0.133) 0.241 (0.168–0.315) 2 (0.7) 1 (0.4) 60 (21.5) 110 (39.4)
Sleeping 0.760 (0.736–0.785) 0.019 (− 0.001 to 0.039) 0.003 (− 0.026 to 0.032) 0.020 (− 0.003 to 0.043) 0.081 (0.023–0.140) 30 (7.2) 1 (0.4) 86 (30.8) 89 (31.9)
Eating 0.987 (0.980–0.995) 0.006 (0.000–0.013) 0.003 (− 0.005 to 0.010) 0.007 (0.001–0.013) 0.013 (− 0.003 to 0.028) 10 (3.6) 5 (1.8) 269 (96.4) 374 (89.2)
Speech 0.959 (0.946–0.972)  − 0.005 (− 0.017 to 0.007)  − 0.020 (− 0.038 to [− 0.002]) 0.002 (− 0.013 to 0.016) 0.006 (− 0.030 to 0.043) 2 (0.7) 2 (0.7) 242 (86.7) 237 (84.9)
Excretion 0.878 (0.815–0.860)  − 0.013 (− 0.037 to 0.010)  − 0.048 (− 0.082 to [− 0.014]) 0.007 (− 0.020 to 0.034) 0.023 (− 0.065 to 0.072) 1 (0.4) 20 (7.2) 151 (54.1) 142 (50.9)
Usual activities 0.758 (0.732–0.783) 0.030 (0.007–0.053)  − 0.011 (− 0.044 to 0.023) 0.040 (0.013–0.067) 0.130 (0.062–0.199) 6 (2.2) 5 (1.8) 97 (34.8) 116 (41.6)
Mental functions 0.876 (0.855–0.897)  − 0.013 (− 0.032 to 0.005)  − 0.040 (− 0.069 to [− 0.011]) 0.003 (− 0.020 to 0.027) 0.003 (− 0.056 to 0.062) 1 (0.4) 1 (0.4) 185 (66.3) 179 (64.2)
Discomfort and symptoms 0.671 (0.645–0.697) 0.051 (0.026–0.075) 0.025 (− 0.011 to 0.060) 0.056 (0.028–0.085) 0.140 (0.066–0.215) 3 (1.1) 14 (5.0) 49 (17.6) 77 (27.6)
Depression 0.890 (0.873–0.907) 0.010 (− 0.005 to 0.025)  − 0.007 (− 0.030 to 0.015) 0.013 (− 0.004 to 0.031) 0.069 (0.024–0.115) 1 (0.4) 3 (1.1) 162 (58.1) 177 (63.4)
Distress 0.870 (0.851–0.888) 0.024 (0.006–0.042) 0.011 (− 0.014 to 0.036) 0.025 (0.005–0.045) 0.072 (0.020–0.123) 1 (0.4) 10 (3.6) 159 (57.0) 180 (64.5)
Vitality 0.734 (0.715–0.753) 0.054 (0.035–0.073) 0.026 (− 0.002 to 0.053) 0.058 (0.036–0.081) 0.145 (0.088–0.202) 5 (1.8) 8 (2.9) 42 (15.1) 76 (27.2)
Sexual activity 0.671 (0.638–0.705) 0.026 (0.001–0.052)  − 0.001 (− 0.039 to 0.038) 0.026 (− 0.005 to 0.057) 0.148 (0.068–0.227) 18 (6.8) 20 (7.2) 92 (33.0) 102 (36.6)
  1. BL, Baseline; CABG, coronary artery bypass grafting; CI, confidence interval; OMT, optimal medical therapy; PCI, percutaneous coronary intervention; PHQ-2, two-item Patient Health Questionnaire; RDS, Rose Dyspnea Scale; SAQ-AF, Seattle Angina Questionnaire Angina Frequency; SAQ-PL, Seattle Angina Physical Limitation; SAQ-QL, Seattle Angina Quality of Life; SAQ-7, Seattle Angina Questionnaire short-form; SD, Standard Deviation; 1 yr, one-year; 15D, 15-dimensional instrument
  2. aAdjusted for baseline scores