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Table 1 Characteristics of the studies on health-related quality of life in children and adolescents with idiopathic nephrotic syndrome

From: Reliability of generic quality-of-life instruments in assessing health-related quality of life among children and adolescents with idiopathic nephrotic syndrome: a systematic review

Study (first author’s name and year of publication) Country of study Study setting Study population (sample size and age/sex distribution) Study design
Rüth et al. [21] Switzerland Zurich University hospital 45 subjects/controls
Median ages at diagnosis: 9.8 years (3.4–19.8 years) for subjects and 5.9 years (0.1–16.3 years) for controls
Cross-sectional, case–control study
Selewski et al. [22] United States Multi-center setting (Midwest Pediatric Nephrology Consortium) 127 subjects (67 with prevalent NS and 60 with incident NS)
Age range: 8–12 years (67 subjects) and 13–17 years (60 subjects)
Male/Female (83 subjects/44 subjects)
Longitudinal cohort study
Rahman et al. [15] Bangladesh Dhaka Medical College Hospital 50 subjects
Age range: 2–12 years (mean age: 7 ± 2.92 years)
Male/Female (29 subjects/21 subjects)
Prospective cross-sectional study
Agrawal et al. [17] India Tertiary health facility in southern India 50 subjects and 50 controls
Age range: 2–18 years
Male/Female (30 subjects or controls/20 subjects or controls)
Cross-sectional, case–control study
Khanjari et al. 23] Iran Ali Asghar & Pediatric Medical Centers
Mofid hospital, Tehran
38 subjects and 38 controls
Age range: 8–12 years (mean age: 9.63 ± 1.49 years for subjects, 9.42 ± 1.51 years for controls)
Male/Female (25/13 subjects and 26/12 controls)
A prospective, case–control study
Roussel et al. [16] France Pediatric Nephrology centers in France 110 subjects
Age range:7–17 years (mean age: 11.6 years)
Cross-sectional observational study
Troost et al. [24] United States
Multi-center tertiary health-facility settings in the United States and Canada 56 subjects with incident INS* & 65 subjects with prevalent INS (PROMIS-II)
87 subjects with incident INS & 172 prevalent INS (NEPTUNE)
Age ranges: 8–17 years (children)
 > 18 years (adults)
Longitudinal cohort study (PROMIS-II and NEPTUNE)
Solarin et al. [25] Nigeria Tertiary health facility in Lagos 61 subjects
Age range: 2–18 years (mean age: 5 ± 3.39 years)
Male/Female (37 subjects/24 subjects)
A prospective, cross-sectional study
Jabbar et al. [26] Iraq Pediatric clinics at two hospitals in Baghdad 50 subjects/50 controls
Age range:2–12 years
Prospective case–control study
Eid et al. [10] Egypt Mansoura University Children’s hospital 300 subjects (100 subjects with INS & 200 matched controls: healthy & chronic non-renal illness groups) Prospective case–control study
  1. PROMIS-II, Patient-reported outcomes measurement information systems II; NEPTUNE, Nephrotic syndrome study network consortium; INS, idiopathic nephrotic syndrome; *Disease duration at baseline < 30 days; Disease duration at baseline ≥ 30 days