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Table 3 Measures of responsiveness for health outcome measures

From: Validity and responsiveness of EQ-5D-5L and SF-6D in patients with health complaints attributed to their amalgam fillings: a prospective cohort study of patients undergoing amalgam removal

  Mean (SD) Paired t-test Responsiveness
Baseline Follow-up ∆Mean (SD) p value ES (SE) SRM (SE) RE (SE)
EQ-5D-5L 0.61(0.22) 0.77 (0.16) 0.158 (0.207) < 0.001 0.73 (0.17) 0.76 (0.18) 0.90 (0.58)
EQ-5D-CW 0.51(0.23) 0.67 (0.17) 0.162 (0.220) 0.002 0.70 (0.16) 0.75 (0.19) 0.84 (0.57)
SF-6D 0.60 (0.10) 0.65 (0.12) 0.056 (0.084) 0.001 0.58 (0.19) 0.67 (0.23) 0.68 (0.34)
GHCr-indexa 76.72 (17.75) 89.49 (14.36) 12.78 (15.87) < 0.001 0.72 (0.19) 0.81 (0.18) 1 (Ref.)
EQ-VAS 49.90 (18.21) 62.44 (16.72) 12.53 (15.23) < 0.001 0.69 (0.17) 0.82 (0.19) 1.05 (0.48)
  1. a GHCr-index has been used as a reference in the calculation of RE. ΔMean Mean change between baseline and follow-up; SD standard deviation; SE bootstrapped standard error (with 1000 iterations); ES effect size; SRM standardized response mean; RE relative efficiency; EQ-5D-5L EuroQol 5-dimensional 5-level questionnaire; EQ-5D-CW EQ-5D cross-walk; SF-6D Short-form 6-dimension; GHCr (reversed) general health complaints; EQ-VAS (EuroQol) visual analogue scale