Impact of subthreshold depression on health-related quality of life in patients with Parkinson’s disease based on cognitive status

Table 1 Clinical and sociodemographic characteristics of patients with MOCA score ≥ 21 based on depression level

	Nondepressed		Subthreshold depression		Depression		p
	n	%	n	%	n	%	p
Sex
Female	18	16.7	14	31.8	17	47.2	0.21
Male	38	67.9	30	68.2	19	52.8
Education level
Low	9	17.0	5	12.2	3	9.7	0.40
Middle	14	26.4	16	39.0	15	48.4
High	30	56.6	20	48.8	13	41.9

	Nondepressed		Subthreshold depression		Depression		p
	M	SD	M	SD	M	SD	p
Age (years)	68.8	8.3	68.1	7.9	67.7	8.0	0.697
Disease duration (years)	7.9	5.1	6.7	5.2	7.1	5.7	0.463
Hoehn and Yahr stage	3 ^a	1	3 ^b	0	3 ^c	0	0.009
MDS-UPDRS III	22.6	12.3	25.9	12.2	28.4	15.6	0.176
NMS-Quest	7.4^a	4.1	9.7^b	3.8	14.1^c	4.9	< 0.001
BDI II II	5.2^a	2.3	11.5^b	2.0	23.6^c	8.3	< 0.001
MOCA	24.8	2.5	24.2	2.6	23.9	2.3	0.183

Data are presented as mean and SD and for Hoehn and Yahr as median and IQR. Data were analyzed using the Kruskal–Wallis test with Bonferroni-correction. Post-hoc tests for NMS-Q ab p = 0.043, bc p = 0.004, ac p < 0.001; for BDI II ab p < 0.001, bc p < 0.001, ac p < 0.001; for Hoehn and Yahr stage ab p = 0.03, bc p = 0.4, ac p = 0.004.

ISSN: 1477-7525