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Table 4 DrHy-Q total scores by socio-demographic and clinical characteristics of patients

From: Drug Hypersensitivity Quality of Life Questionnaire: validation procedures and first results of the Portuguese version

 

N

(%)

Mean

SD

p value

Gender

 Female

157

(78.1)

36.8

12.3

0.95

 Male

44

(21.9)

36.9

12.7

 

Age

 ≤ 38 years

69

(34.3)

32.4

10.5

0.001

 39–51

68

(31.8)

38.1

13.1

 

 > 51

64

(31.8)

40.2

13.0

 

Academics studies

 ≤ 6 years

14

(18.4)

41.9

11.5

0.058

 7–12

34

(44.7)

33.2

11.7

 

 > 12

28

(36.8)

34.2

11.3

 

Atopy

 Yes

58

(29.6)

38.9

13.2

0.120

 No

138

(70.4)

35.9

12.1

 

Co-morbidities

 Yes

118

(59.0)

38.5

13.3

0.025

 No

82

(41.0)

34.4

11.3

 

Daily medication

 Yes

114

(57.0)

39.1

13.0

0.002

 No

86

(43.0)

33.7

11.4

 

Family history of drug allergy

 Yes

12

(6.1)

29.8

11.1

0.047

 No

186

(93.9)

37.2

12.6

 

Δ reaction- study

 ≤ 2 years

56

(33.3)

37.2

13.3

0.216

 2 e 5

50

(29.8)

33.4

7.9

 

 > 5

62

(36.9)

36.8

14.2

 

Type of reaction

 Immediate

102

(51.5)

38.3

13.5

0.132

 Non-Immediate

80

(40.4)

34.6

10.9

 

 Unknown

16

(8.1)

38.3

14.5

 

Clinical manifestations

 Anaphylaxis

79

(40.9)

41.0

13.4

0.002

 Urticaria/Angioedema

40

(20.7)

39.2

12.5

 

 MPE

46

(23.8)

32.7

10.2

 

 Other

28

(14.5)

36.9

13.6

 

Severity of reaction

 Severe

45

(23.3)

41.1

13.8

0.008

 Moderate

58

(30.1)

36.9

12.1

 

 Mild

90

(46.6)

34.1

11.2

 

Number of reactions

 1

127

(65.1)

34.4

12.8

0.002

 ≥ 2

68

(34.9)

40.3

11.1

 

Number of suspected drugs

 1

140

(70.4)

35.2

13.0

0.014

 ≥ 2

59

(29.6)

39.9

10.4

 

Class of drug

Â ĂŸL antibiotics

    

0.009

  Confirmed

46

(34.6)

39.3

12.7

 

  Excluded

87

(65.4)

33.5

11.8

 

 Non-ĂŸL antibiotics

    

0.067

  Confirmed

10

(28.6)

41.0

11.6

 

  Excluded

25

(71.4)

33.8

9.4

 

 NSAID

    

0.820

  Confirmed

26

(65.0)

42.9

13.1

 

  Excluded

14

(35.0)

41.9

13.1

 

 RCM

    

0.324

  Confirmed

7

(46.7)

33.9

12.0

 

  Excluded

8

(53.3)

40.4

12.5

 
  1. Bold values indicate statistical significance (p < 0.05)
  2. SD, standard deviation; MPE, Maculopapular exanthema; DH, Drug hypersensitivity