| N | (%) | Mean | SD | p value |
---|---|---|---|---|---|
Gender | |||||
 Female | 157 | (78.1) | 36.8 | 12.3 | 0.95 |
 Male | 44 | (21.9) | 36.9 | 12.7 |  |
Age | |||||
 ≤ 38 years | 69 | (34.3) | 32.4 | 10.5 | 0.001 |
 39–51 | 68 | (31.8) | 38.1 | 13.1 |  |
 > 51 | 64 | (31.8) | 40.2 | 13.0 |  |
Academics studies | |||||
 ≤ 6 years | 14 | (18.4) | 41.9 | 11.5 | 0.058 |
 7–12 | 34 | (44.7) | 33.2 | 11.7 |  |
 > 12 | 28 | (36.8) | 34.2 | 11.3 |  |
Atopy | |||||
 Yes | 58 | (29.6) | 38.9 | 13.2 | 0.120 |
 No | 138 | (70.4) | 35.9 | 12.1 |  |
Co-morbidities | |||||
 Yes | 118 | (59.0) | 38.5 | 13.3 | 0.025 |
 No | 82 | (41.0) | 34.4 | 11.3 |  |
Daily medication | |||||
 Yes | 114 | (57.0) | 39.1 | 13.0 | 0.002 |
 No | 86 | (43.0) | 33.7 | 11.4 |  |
Family history of drug allergy | |||||
 Yes | 12 | (6.1) | 29.8 | 11.1 | 0.047 |
 No | 186 | (93.9) | 37.2 | 12.6 |  |
Δ reaction- study | |||||
 ≤ 2 years | 56 | (33.3) | 37.2 | 13.3 | 0.216 |
 2 e 5 | 50 | (29.8) | 33.4 | 7.9 |  |
 > 5 | 62 | (36.9) | 36.8 | 14.2 |  |
Type of reaction | |||||
 Immediate | 102 | (51.5) | 38.3 | 13.5 | 0.132 |
 Non-Immediate | 80 | (40.4) | 34.6 | 10.9 |  |
 Unknown | 16 | (8.1) | 38.3 | 14.5 |  |
Clinical manifestations | |||||
 Anaphylaxis | 79 | (40.9) | 41.0 | 13.4 | 0.002 |
 Urticaria/Angioedema | 40 | (20.7) | 39.2 | 12.5 |  |
 MPE | 46 | (23.8) | 32.7 | 10.2 |  |
 Other | 28 | (14.5) | 36.9 | 13.6 |  |
Severity of reaction | |||||
 Severe | 45 | (23.3) | 41.1 | 13.8 | 0.008 |
 Moderate | 58 | (30.1) | 36.9 | 12.1 |  |
 Mild | 90 | (46.6) | 34.1 | 11.2 |  |
Number of reactions | |||||
 1 | 127 | (65.1) | 34.4 | 12.8 | 0.002 |
 ≥ 2 | 68 | (34.9) | 40.3 | 11.1 |  |
Number of suspected drugs | |||||
 1 | 140 | (70.4) | 35.2 | 13.0 | 0.014 |
 ≥ 2 | 59 | (29.6) | 39.9 | 10.4 |  |
Class of drug | |||||
Â ĂŸL antibiotics |  |  |  |  | 0.009 |
  Confirmed | 46 | (34.6) | 39.3 | 12.7 |  |
  Excluded | 87 | (65.4) | 33.5 | 11.8 |  |
 Non-ĂŸL antibiotics |  |  |  |  | 0.067 |
  Confirmed | 10 | (28.6) | 41.0 | 11.6 |  |
  Excluded | 25 | (71.4) | 33.8 | 9.4 |  |
 NSAID |  |  |  |  | 0.820 |
  Confirmed | 26 | (65.0) | 42.9 | 13.1 |  |
  Excluded | 14 | (35.0) | 41.9 | 13.1 |  |
 RCM |  |  |  |  | 0.324 |
  Confirmed | 7 | (46.7) | 33.9 | 12.0 |  |
  Excluded | 8 | (53.3) | 40.4 | 12.5 |  |