|
Cut-point
|
Hospital setting (N = 492)
|
Community setting (N = 400)
|
|---|
|
≥ 2
|
≥ 3
|
≥ 2
|
≥ 3
|
|---|
|
EQ-5D-3L Anxiety/depression dimension
| | | | |
|
Sensitivity
|
75.0%
|
17.7%
|
74.6%
|
14.9%
|
|
Specificity
|
69.8%
|
98.0%
|
82.6%
|
98.2%
|
|
LR+
|
2.48
|
9.00
|
4.28
|
8.28
|
|
LR−
|
0.36
|
0.84
|
0.31
|
0.87
|
|
PPV
|
48.0%
|
76.6%
|
45.0%
|
61.2%
|
|
NPV
|
88.3%
|
76.3%
|
94.5%
|
85.8%
|
|
AUROC (95% CI)
|
0.74 (0.70, 0.79)
|
0.79 (0.74, 0.85)
|
|
EQ-5D-3L index score tertiles
| | | | |
|
Sensitivity
|
52.2%
|
14.7%
|
25.4%
|
4.5%
|
|
Specificity
|
30.3%
|
62.8%
|
34.4%
|
68.3%
|
|
LR+
|
0.75
|
0.39
|
0.39
|
0.14
|
|
LR−
|
1.58
|
1.36
|
2.17
|
1.40
|
|
PPV
|
21.7%
|
12.8%
|
6.9%
|
2.6%
|
|
NPV
|
63.2%
|
66.6%
|
70.8%
|
79.0%
|
|
AUROC (95% CI)
|
0.37 (0.32, 0.42)
|
0.27 (0.22, 0.33)
|
|
EQ-VAS score tertiles
| | | | |
|
Sensitivity
|
52.9%
|
13.2%
|
41.8%
|
10.5%
|
|
Specificity
|
32.4%
|
73.0%
|
30.5%
|
68.0%
|
|
LR+
|
0.78
|
0.49
|
0.60
|
0.33
|
|
LR−
|
1.45
|
1.19
|
1.91
|
1.32
|
|
PPV
|
22.5%
|
15.3%
|
10.3%
|
5.9%
|
|
NPV
|
65.0%
|
69.5%
|
73.3%
|
80.0%
|
|
AUROC (95% CI)
|
0.40 (0.33, 0.47)
|
0.33 (0.27, 0.39)
|
- LR+, positive likelihood ratio; LR−, negative likelihood ratio; AUROC, area under receiver operating curve. EQ-5D-3L index score tertiles: 2 = quintile 2, 3 = quintile 3. EQ-5D-3L anxiety/depression dimension: 2 = moderately anxious or depressed, 3 = extremely anxious or depressed. PPV, positive predictive value; NPV, negative predictive value. Bolded values indicate the cut-point that maximizes sensitivity and specificity for each component
