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Table 4 The MANCOVA model explaining PHE-s® and SIBD-Q association and the influence of socio-demographic and clinical variables. Only statistically significant socio-demographic and clinical variables have been included in the table

From: Does patient engagement affect IBD patients’ health-related quality of life? Findings from a cross-sectional study among people with inflammatory bowel diseases

  Dependent Variable Sum of Squares df Mean Square F p
PHE-s® Levels SIBD-Q Total 264.66 3 88.221 95.629  < .001
  SIBD-Q Systemic symptoms 286.73 3 95.575 94.472  < .001
  SIBD-Q Social Functioning 293.71 3 97.905 56.848  < .001
  SIBD-Q Bowel Symptoms 233.65 3 77.882 55.074  < .001
  SIBD-Q Emotional functioning 308.10 3 102.700 84.294  < .001
Gender SIBD-Q Total 13.54 1 13.536 14.672  < .001
  SIBD-Q Systemic symptoms 13.51 1 13.506 13.351  < .001
  SIBD-Q Social Functioning 4.14 1 4.138 2.402 0.122
  SIBD-Q Bowel Symptoms 21.12 1 21.123 14.937  < .001
  SIBD-Q Emotional functioning 11.29 1 11.292 9.269 0.002
Relapses in the last 12 moths SIBD-Q Total 69.03 4 17.259 18.708  < .001
  SIBD-Q Systemic symptoms 79.19 4 19.796 19.568  < .001
  SIBD-Q Social Functioning 140.76 4 35.191 20.433  < .001
  SIBD-Q Bowel Symptoms 73.76 4 18.439 13.039  < .001
  SIBD-Q Emotional functioning 45.61 4 11.403 9.359  < .001
PHE-s®_Levels * Gender SIBD-Q Total 3.39 3 1.130 1.225 0.300
  SIBD-Q Systemic symptoms 2.87 3 0.956 0.945 0.418
  SIBD-Q Social Functioning 1.40 3 0.467 0.271 0.846
  SIBD-Q Bowel Symptoms 2.56 3 0.854 0.604 0.613
  SIBD-Q Emotional functioning 5.85 3 1.951 1.601 0.188
PHE-s®_Levels * Relapses in the last 12 moths SIBD-Q Total 9.09 10 0.909 0.986 0.455
  SIBD-Q Systemic symptoms 10.56 10 1.056 1.044 0.405
  SIBD-Q Social Functioning 20.15 10 2.015 1.170 0.309
  SIBD-Q Bowel Symptoms 14.52 10 1.452 1.027 0.419
  SIBD-Q Emotional functioning 8.13 10 0.813 0.667 0.755
Gender * Relapses in the last 12 moths SIBD-Q Total 6.51 3 2.171 2.353 0.071
  SIBD-Q Systemic symptoms 6.84 3 2.281 2.255 0.081
  SIBD-Q Social Functioning 9.83 3 3.276 1.902 0.128
  SIBD-Q Bowel Symptoms 9.61 3 3.204 2.266 0.080
  SIBD-Q Emotional functioning 5.04 3 1.682 1.380 0.248
PHE-s®_Levels * Gender * Relapses in the last 12 moths SIBD-Q Total 7.67 7 1.096 1.188 0.308
  SIBD-Q Systemic symptoms 7.29 7 1.041 1.029 0.410
  SIBD-Q Social Functioning 13.00 7 1.857 1.078 0.376
  SIBD-Q Bowel Symptoms 5.14 7 0.734 0.519 0.820
  SIBD-Q Emotional functioning 15.52 7 2.216 1.819 0.081
Residuals SIBD-Q Total 466.80 506 0.923   
  SIBD-Q Systemic symptoms 511.91 506 1.012   
  SIBD-Q Social Functioning 871.45 506 1.722   
  SIBD-Q Bowel Symptoms 715.55 506 1.414   
  SIBD-Q Emotional functioning 616.49 506 1.218