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Table 4 Cox regression survival analysis examining the effect of ABRP and XDR infections (Model 1 and 2, respectively) on 2-year mortality, after adjusting for possible covariates of severe underlying illness

From: The role of antimicrobial resistance on long-term mortality and quality of life in critically ill patients: a prospective longitudinal 2-year study

 

Model 1

Model 2

HR

95% CI

P value

HR

95% CI

P value

Lower

Upper

Lower

Upper

APACHE II

1.099

1.075

1.124

 < 0.001

1.100

1.076

1.125

 < 0.001

MODS score27

1.146

1.083

1.213

 < 0.001

1.140

1.077

1.207

 < 0.001

ARDS

0.786

0.553

1.115

0.177

0.797

0.563

1.128

0.200

CRRT

1.248

0.776

2.007

0.360

1.384

0.866

2.213

0.174

MV prior to infection

0.741

0.494

1.111

0.147

0.707

0.470

1.062

0.095

Cardiac arrest

1.030

0.641

1.657

0.901

1.026

0.638

1.650

0.915

ABRP infections

1.778

1.166

2.711

0.008

XDR infections

1.889

1.075

3.320

0.027

  1. ABRP antibiotic resistant pathogens, XDR extensively-drug resistant pathogens, CI confidence interval, HR hazard ratio, APACHE II Acute Physiology and Chronic Health Evaluation Score II, MODS multiple organ dysfunction syndrome, ARDS acute respiratory distress syndrome, CRRT continuous renal replacement therapy, MV mechanical ventilation
  2. Variables included in the Models were assessed for multicolinearity issues; All Variable Inflation Factors (VIF) ≤ 1.796