Responsiveness and interpretability of commonly used outcome assessments of mobility capacity in older hospital patients with cognitive spectrum disorders

Table 5 Responsiveness of the 10 measurement instruments of mobility (n = 63)

Instrument	Anchor	n	rho	AUC statistics
Instrument	Anchor	n	rho	AUC	95% CI	P
de Morton Mobility Index	P-GRC-A	58	0.40	73	60–86	< 0.01
	T-GRC-A	55	0.35	70	56–84	0.01
	FAC-C	61	0.43	76	62–90	< 0.01
Hierarchical Assessment of Balance and Mobility	P-GRC-A	58	0.25	64	50–79	0.06
	T-GRC-A	55	0.30	67	52–81	0.04
	FAC-C	61	0.29	68	54–81	0.03
Performance Oriented Mobility Assessment	P-GRC-A	58	0.25	65	50–79	0.06
	T-GRC-A	55	0.35	70	55–85	0.01
	FAC-C	61	0.51	81	68–95	< 0.01
Short Physical Performance Battery	P-GRC-A	58	0.32	68	54–82	0.02
	T-GRC-A	55	0.35	69	55–83	0.02
	FAC-C	61	0.51	79	67–91	< 0.01
4-m gait speed test	P-GRC-A	27	0.24	64	42–86	0.22
	T-GRC-A	25	0.13	57	34–81	0.54
	FAC-C	27	− 0.09	44	22–67	0.64
5 × chair rise test	P-GRC-A	15	− 0.50	80	56–100	0.06
	T-GRC-A	14	− 0.14	58	24–93	0.61
	FAC-C	15	− 0.35	73	46–99	0.19
2-min walk test	P-GRC-A	28	0.42	75	54–95	0.03
	T-GRC-A	25	0.30	68	46–89	0.14
	FAC-C	28	− 0.03	48	26–70	0.87
Timed Up and Go test	P-GRC-A	24	− 0.09	55	32–79	0.66
	T-GRC-A	22	0.12	43	18–68	0.57
	FAC-C	24	−0.11	57	32–81	0.60
Barthel Index mobility subscale	P-GRC-A	58	0.23	63	49–77	0.09
	T-GRC-A	55	0.27	65	50–79	0.07
	FAC-C	61	0.41	74	60–88	< 0.01
Functional Ambulation Categories	P-GRC-A	58	0.36	68	54–82	0.02
	T-GRC-A	55	0.33	66	51–81	0.04
	FAC-C	na	na	na	na	na

Bold vales are considered valid based on a Spearman’s rho correlation of ≥ 0.3 between the instrument’s change scores and the anchor
AUC area under the curve, P-GRC-A patient-reported global rating of change amount scale, T-GRC-A therapist-reported global rating of change amount scale, FAC-C Functional Ambulation Categories change anchor, na not applicable
Anchor P-GRC-A: included in analysis (n = 58): unchanged (n = 32), changed/improved (n = 26); excluded (n = 5): deteriorated (n = 3), GRC missing (n = 2)
Anchor T-GRC-A: included in analysis (n = 55): unchanged (n = 29), changed/improved (n = 26); excluded (n = 8): deteriorated (n = 2), GRC missing (n = 6)
Anchor FAC-C: included in analysis (n = 61): unchanged (n = 41), changed/improved (n = 20); excluded (n = 2): deteriorated (n = 2), GRC missing (n = 0)

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