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Table 1 Characteristics of samples in three randomized controlled trials (RCTs)

From: Responsiveness of PROMIS and Patient Health Questionnaire (PHQ) Depression Scales in three clinical trials

Clinical population Sample 1 CAMEO RCT (N1 = 153) Sample 2 SPACE RCT (N2 = 240) Sample 3 SSM RCT (N3 = 258)
Chronic low back pain Chronic musculoskeletal pain Stroke survivors
Recruitment setting Primary care Primary care Neurology
Age, mean (SD) 58.1 (9.3) 58.3 (13.7) 61.7 (10.8)
Male, n (%) 140 (91.5) 208 (86.7) 209 (81.0)
Race, n (%)    
 White 111 (72.5) 207 (86.2) 166 (64.3)
 Black 37 (24.2) 18 (7.5) 78 (30.2)
 Other 5 (3.3) 15 (6.3) 14 (5.4)
Education, n (%)    
 Less than high school 8 (5.2) 6 (2.5) 31 (12.2)
 High school 49 (32.0) 71 (29.6) 85 (33.3)
 Technical school or some college 74 (48.4) 103 (42.9) 80 (31.4)
 College degree or greater 22 (14.4) 60 (25.0) 59 (23.1)
Marital status, n (%)    
 Married 81 (52.9) 135 (56.5) 135 (52.5)
 Divorced 43 (28.1) 60 (25.1) 68 (26.5)
 Other 29 (19.0) 44 (18.4) 54 (21.0)
PROMIS T-scores, mean (SD)    
 Depression 4-item 53.5 (9.9) 50.3 (9.1) 51.3 (9.2)
 Depression 6-item 53.2 (10.3) 49.9 (9.5) 50.5 (10.0)
 Depression 8-item 53.0 (10.2) 49.6 (9.5) 50.3 (9.9)
 Depression short-form 53.0 (10.3) 49.7 (9.7) 50.0 (10.3)
PHQ-9 depression score, mean (SD) 11.1 (6.2) 6.2 (5.0) 7.7 (6.2)
Cross-sectional Global Ratings of Depression (0–4), mean (SD) 2.5 (1.0) 2.0 (0.9) 1.9 (1.0)
DSM-V depressive disorder, n (%)    
 Major depression 68 (44.4) 36 (15.0) 66 (25.6)
 Minor depression 21 (13.7) 23 (9.6) 21 (8.1)
Disability days in the past 4 weeks, mean (SD) 16.3 (8.6) 10.3 (9.0) 5.1 (7.7)
  1. CAMEO CAre Management for the Effective use of Opioids trial, SPACE Strategies for Prescribing Analgesics Comparative Effectiveness trial, SSM Stroke survivor Self-Management trial