Table 4 Pre- and Post-treatment mean PedsQL scores of patients in groups A and B and of healthy controls: parent-proxy report
Healthy controls (N = 999) | Group A (N = 66) | Group B (N = 22) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Pre-treatment | Pre-treatment vs. Healthy controls | After CR | After CR vs. Healthy controls | After CR vs. Pre-treatment | Pre-treatment | Pre-treatment vs. Healthy controls | 12 months after initiation of treatment | 12 months after initiation of treatment vs. Healthy controls | After 12 months of initiation of treatment vs. Pre-treatment | ||
Total score | 85.5 ± 13.4 | 84.4 ± 12.6 | P 0.376 ES − 0.88 [− 0.33, 0.17] | 89.5 ± 10.4 | P 0.038 ES 0.3 [0.05, 0.55] | P 0.012 ES 0.44 [0.09, 0.8] | 88.0 ± 9.5 | P 0.681 ES 0.19 [− 0.24, 0.61] | 90.5 ± 11.0 | P 0.086 ES 0.37 [− 0.05, 0.8] | P 0.915 ES 0.24 [− 0.37, 0.85] |
Physical Health Domain | 86.2 ± 19.9 | 87.7 ± 14.6 | P 0.812 ES 0.08 [− 0.18, 0.33] | 94.2 ± 9.0 | P 0.013 ES 0.41 [0.15, 0.67] | P 0.012 ES 0.54 [0.19,0.89] | 94.5 ± 12.9 | P 0.062 ES 0.42 [0, 0.84] | 95.8 ± 7.6 | P 0.024 ES 0.49 [− 0.06, 0.91] | P 0.907 ES 0.12 [− 0.49, 0.73] |
Psychosocial Health Domain | 85.2 ± 13.2 | 83.4 ± 13.8 | P 0.314 ES − 0.14 [− 0.39, 0.12] | 87.9 ± 11.2 | P 0.127 ES 0.21 [− 0.05, 0.46] | P 0.061 ES 0.37 [0, 0.72] | 86.2 ± 10.6 | P 0.972 ES 0.08 [− 0.35, 0.5] | 88.7 ± 12.9 | P 0.202 ES 0.27 [− 0.16, 0.69] | P 0.211 ES 0.21 [− 0.4, 0 82] |
Emotional Functioning | 84.5 ± 14.9 | 82.8 ± 15.2 | P 0.365 ES − 0.11 [− 0.37, 0.14] | 88.3 ± 11.2 | P 0.135 ES 0.26 [0, 0.52] | P 0.057 ES 0.41 [0.05, 0.77] | 81.3 ± 14.9 | P 0.293 ES − 0.21 [− 0.64, 0.21] | 89.5 ± 10.9 | P 0.235 ES 0.34 [− 0.09, 076] | P 0.077 ES 0.63 [0, 1.25] |
Social Functioning | 86.5 ± 17.4 | 82.6 ± 21.2 | P 0.237 ES − 0.22 [− 0.48, 0.04] | 87.4 ± 16.0 | P 0.687 ES 0.05 [− 0.2, 0.31] | P 0.269 ES 0.26 [− 0.1, 0.61] | 88.9 ± 17.5 | P 0.47 ES 0.14 [− 0.28, 0.56] | 87.9 ± 18.5 | P 0.825 ES 0.08 [− 0.34, 0.5] | P 0.929 ES − 0.06 [− 0.66, 0.55] |
School Functioning | 84.6 ± 14.2 | 84.6 ± 13.7 | P 0.932 ES 0 [− 0.26, 0.26] | 88.2 ± 12.7 | P 0.055 ES 0.25 [0, 0.51] | P 0.134 ES 0.27 [− 0.08, 0.63] | 88.4 ± 12.7 | P 0.212 ES 0.27[− 0.15, 0.69] | 88.7 ± 13.9 | P 0.127 ES − 0.29 [− 0.13, 0.71] | P 0.594 ES − 0.02 [− 0.59, 0. 63] |