Factors | EQ-5D-3L utility values | EQ VAS | ||||||
---|---|---|---|---|---|---|---|---|
Mean (SD) | Median (IQR) | p value¶ | Effect size | Mean (SD) | Median (IQR) | p value¶ | Effect size | |
Total sample | 0.893 (0.167) | 1.000 (0.269) | – | – | 81.22 (16.92) | 85.00 (25.00) | – | – |
Source of survey | Â | Â | Â | Â | Â | Â | Â | Â |
 Self-reported | 0.887 (0.165) | 1.000 (0.269) | 0.219 | 0.080 | 78.08 (18.19) | 80.00 (20.00) | < 0.001* | 0.439 |
 Proxy-reported | 0.900 (0.169) | 1.000 (0.255) | 85.36 (14.10) | 90.00 (15.00) | ||||
Gender | Â | Â | Â | Â | Â | Â | Â | Â |
 Male | 0.911 (0.157) | 1.000 (0.244) | 0.011* | 0.202 | 82.29 (15.53) | 85.00 (20.00) | 0.450 | 0.114 |
 Female | 0.878 (0.173) | 1.000 (0.269) | 80.37 (17.93) | 85.00 (25.00) | ||||
Category | Â | Â | Â | Â | Â | Â | Â | Â |
 Child (≤ 18 years old) | 0.898 (0.163) | 1.000 (0.255) | 0.079 | 0.371 | 84.97 (15.16) | 90.00 (15.00) | < 0.001* | 0.611 |
 Adult | 0.884 (0.172) | 1.000 (0.269) | 75.04 (17.86) | 80.00 (25.00) | ||||
Presence of iron overload complication | Â | Â | Â | Â | Â | Â | Â | Â |
 Absent | 0.911 (0.153) | 1.000 (0.244) | 0.002* | 0.257 | 83.31 (16.61) | 85.00 (15.00) | < 0.001* | 0.288 |
 Present | 0.869 (0.180) | 1.000 (0.269) | 78.49 (16.70) | 80.00 (20.00) | ||||
Route of iron chelating therapy | Â | Â | Â | Â | Â | Â | Â | Â |
 Subcutaneous (SC) only | 0.877 (0.187) | 1.000 (0.269) | 0.016¥,* | Reference Group | 78.45 (15.68) | 80.00 (20.00) | < 0.001¥,* | Reference Group |
 Oral (PO) only | 0.911 (0.151) | 1.000 (0.244) | 0.215 | 83.82 (15.41) | 90.00 (15.00) | 0.347 | ||
 SC + PO | 0.866 (0.181) | 1.000 (0.269) | 0.060 | 77.60 (19.06) | 80.00 (20.00) | 0.047 | ||
Number of iron chelating agents | Â | Â | Â | Â | Â | Â | Â | Â |
 Monotherapy | 0.908 (0.153) | 1.000 (0.255) | 0.005* | 0.274 | 82.95 (15.52) | 87.50 (20.00) | < 0.001* | 0.299 |
 Dual therapy | 0.863 (0.186) | 1.000 (0.269) | 77.90 (18.95) | 80.00 (20.00) | ||||
History of serious adverse event with iron chelating therapy | Â | Â | Â | Â | Â | Â | Â | Â |
 Yes | 0.881 (0.181) | 1.000 (0.269) | 0.585 | 0.078 | 78.16 (17.52) | 85.00 (20.00) | 0.068 | 0.208 |
 No | 0.894 (0.164) | 1.000 (0.269) | 81.67 (16.80) | 80.00 (20.00) |